A meta-analysis of genome-wide association studies identifies multiple longevity genes
出版年份 2019 全文链接
标题
A meta-analysis of genome-wide association studies identifies multiple longevity genes
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-08-14
DOI
10.1038/s41467-019-11558-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genetic analyses of diverse populations improves discovery for complex traits
- (2019) Genevieve L. Wojcik et al. NATURE
- Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study
- (2018) Anatoliy I Yashin et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer
- (2018) Valentina Grossi et al. NUCLEIC ACIDS RESEARCH
- Quantitative analysis of population-scale family trees with millions of relatives
- (2018) Joanna Kaplanis et al. SCIENCE
- Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
- (2018) Alvaro N. Barbeira et al. Nature Communications
- APOE Alleles and Extreme Human Longevity
- (2018) Paola Sebastiani et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Facing up to the global challenges of ageing
- (2018) Linda Partridge et al. NATURE
- Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating
- (2018) J. Graham Ruby et al. GENETICS
- Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
- (2018) Niels van den Berg et al. Nature Communications
- Association of Accelerometer-Measured Physical Activity With Leukocyte Telomere Length Among Older Women
- (2017) Aladdin H Shadyab et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Four Genome-Wide Association Studies Identify New Extreme Longevity Variants
- (2017) Paola Sebastiani et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Limitations and risks of meta-analyses of longevity studies
- (2017) Paola Sebastiani et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
- (2017) Peter K. Joshi et al. Nature Communications
- Bayesian association scan reveals loci associated with human lifespan and linked biomarkers
- (2017) Aaron F. McDaid et al. Nature Communications
- Identification and characterization of two functional variants in the human longevity gene FOXO3
- (2017) Friederike Flachsbart et al. Nature Communications
- APOE gene polymorphism in long-lived individuals from a central China population
- (2017) Guodong Liu et al. Scientific Reports
- Immunochip analysis identifies association of theRAD50/IL13region with human longevity
- (2016) Friederike Flachsbart et al. AGING CELL
- PhenoScanner: a database of human genotype–phenotype associations
- (2016) James R. Staley et al. BIOINFORMATICS
- LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
- (2016) Jie Zheng et al. BIOINFORMATICS
- GPR78 promotes lung cancer cell migration and metastasis by activation of Gαq-Rho GTPase pathway
- (2016) Dan-Dan Dong et al. BMB Reports
- Genetic landscape of APOE in human longevity revealed by high-throughput sequencing
- (2016) Seungjin Ryu et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Novel loci and pathways significantly associated with longevity
- (2016) Yi Zeng et al. Scientific Reports
- Health and function of participants in the Long Life Family Study: A comparison with other cohorts
- (2016) Anne B. Newman et al. Aging-US
- A proposed panel of biomarkers of healthy ageing
- (2015) Jose Lara et al. BMC Medicine
- Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of “Aging,” “Life Span,” and “Longevity”
- (2015) Paola Sebastiani et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals
- (2014) Marianne Nygaard et al. EXPERIMENTAL GERONTOLOGY
- ApoE gene and exceptional longevity: Insights from three independent cohorts
- (2014) Nuria Garatachea et al. EXPERIMENTAL GERONTOLOGY
- Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
- (2014) Joris Deelen et al. HUMAN MOLECULAR GENETICS
- Smoking Prevalence and Cigarette Consumption in 187 Countries, 1980-2012
- (2014) Marie Ng et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
- (2014) Linda Broer et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
- (2014) Anubha Mahajan et al. NATURE GENETICS
- Quality control and conduct of genome-wide association meta-analyses
- (2014) Thomas W Winkler et al. Nature Protocols
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Letter to the editor: Standardization of genetic association studies, pros and cons, reaffirmed
- (2013) Alexander Kulminski et al. AGE
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Review: a meta-analysis of GWAS and age-associated diseases
- (2012) William R. Jeck et al. AGING CELL
- Health Span Approximates Life Span Among Many Supercentenarians: Compression of Morbidity at the Approximate Limit of Life Span
- (2012) S. L. Andersen et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Large-scale association analysis identifies new risk loci for coronary artery disease
- (2012) Panos Deloukas et al. NATURE GENETICS
- Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
- (2011) Joris Deelen et al. AGING CELL
- Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies
- (2011) Buhm Han et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The yin and yang of the Cdkn2a locus in senescence and aging
- (2011) Darren J. Baker et al. CELL CYCLE
- Sex/Gender Differences in Cardiovascular Disease Prevention
- (2011) Lori Mosca et al. CIRCULATION
- A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals
- (2011) Almut Nebel et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium
- (2010) Anne B. Newman et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Nonagenarian Siblings and Their Offspring Display Lower Risk of Mortality and Morbidity than Sporadic Nonagenarians: The Leiden Longevity Study
- (2009) Rudi G.J. Westendorp et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- The structure and function of G-protein-coupled receptors
- (2009) Daniel M. Rosenbaum et al. NATURE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started