A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier

The Concept of an Ideal Antibiotic: Implications for Drug Design

(2019) Márió Gajdács   MOLECULES

Inhibition of autotransporter biogenesis by small molecules

(2019) Maurice Steenhuis et al.   MOLECULAR MICROBIOLOGY

The Synthetic Phenotype of ΔbamB ΔbamE Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF

(2019) Elizabeth M. Hart et al.   mBio

Envelope stress responses: balancing damage repair and toxicity

(2019) Angela M. Mitchell et al.   NATURE REVIEWS MICROBIOLOGY

Thermal proteome profiling in bacteria: probing protein state in vivo

(2018) André Mateus et al.   Molecular Systems Biology

Monoclonal antibody targeting the β-barrel assembly machine ofEscherichia coliis bactericidal

(2018) Kelly M. Storek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion

(2018) James Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitor of intramembrane protease RseP blocks the σEresponse causing lethal accumulation of unfolded outer membrane proteins

(2018) Anna Konovalova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells

(2018) Chris Soon Heng Tan et al.   SCIENCE

The Escherichia coli β-Barrel Assembly Machinery Is Sensitized to Perturbations under High Membrane Fluidity

(2018) Kelly M. Storek et al.   JOURNAL OF BACTERIOLOGY

Thanatin targets the intermembrane protein complex required for lipopolysaccharide transport in Escherichia coli

(2018) Stefan U. Vetterli et al.   Science Advances

Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly

(2017) Anne L. McCabe et al.   JOURNAL OF BACTERIOLOGY

Envelope Stress Responses: An Interconnected Safety Net

(2017) Marcin Grabowicz et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hit 'em where it hurts: The growing and structurally diverse family of peptides that target lipid-II

(2016) Sabine F. Oppedijk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Multiple Transcriptional Factors Regulate Transcription of therpoEGene inEscherichia coliunder Different Growth Conditions and When the Lipopolysaccharide Biosynthesis Is Defective

(2016) Gracjana Klein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of outer membrane protein insertion by the BAM complex

(2016) Yinghong Gu et al.   NATURE

Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway

(2016) Holly A. Sutterlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CpxQ sRNA Negatively Regulates Skp To Prevent Mistargeting of β-Barrel Outer Membrane Proteins into the Cytoplasmic Membrane

(2016) Marcin Grabowicz et al.   mBio

Lipid-II Independent Antimicrobial Mechanism of Nisin Depends On Its Crowding And Degree Of Oligomerization

(2016) Ashutosh Prince et al.   Scientific Reports

Optimization of the antimicrobial activity of nisin, Na-EDTA and pH against gram-negative and gram-positive bacteria

(2015) Avik Khan et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Selective small-molecule inhibition of an RNA structural element

(2015) John A. Howe et al.   NATURE

MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes

(2014) Graeme C. McAlister et al.   ANALYTICAL CHEMISTRY

Structure and Operation of Bacterial Tripartite Pumps

(2013) Philip Hinchliffe et al.   Annual Review of Microbiology

Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for  -barrel assembly in Escherichia coli

(2013) N. W. Rigel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual Molecular Signals Mediate the Bacterial Response to Outer-Membrane Stress

(2013) S. Lima et al.   SCIENCE

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

(2013) D. M. Molina et al.   SCIENCE

Activation of the Escherichia coli  -barrel assembly machine (Bam) is required for essential components to interact properly with substrate

(2012) D. P. Ricci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substitutions in the BamA  -Barrel Domain Overcome the Conditional Lethal Phenotype of a  bamB  bamE Strain of Escherichia coli

(2011) R. Tellez et al.   JOURNAL OF BACTERIOLOGY

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

Protein Translocation Across the Bacterial Cytoplasmic Membrane

(2007) Arnold J.M. Driessen et al.   Annual Review of Biochemistry