3-Hydroxy-3-Methylglutaric Acid Impairs Redox and Energy Homeostasis, Mitochondrial Dynamics, and Endoplasmic Reticulum–Mitochondria Crosstalk in Rat Brain
出版年份 2019 全文链接
标题
3-Hydroxy-3-Methylglutaric Acid Impairs Redox and Energy Homeostasis, Mitochondrial Dynamics, and Endoplasmic Reticulum–Mitochondria Crosstalk in Rat Brain
作者
关键词
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出版物
NEUROTOXICITY RESEARCH
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-11-13
DOI
10.1007/s12640-019-00122-x
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Experimental Evidence that In Vivo Intracerebral Administration of L-2-Hydroxyglutaric Acid to Neonatal Rats Provokes Disruption of Redox Status and Histopathological Abnormalities in the Brain
- (2018) Rafael Teixeira Ribeiro et al. NEUROTOXICITY RESEARCH
- 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency: A Case Report and Literature Review
- (2018) Ozlem Yilmaz et al. Nutricion Hospitalaria
- Endoplasmic Reticulum–Mitochondrial Contactology: Structure and Signaling Functions
- (2018) György Csordás et al. TRENDS IN CELL BIOLOGY
- A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease
- (2018) Estela Area-Gomez et al. Cell Death & Disease
- Tau Phosphorylation, Molecular Chaperones, and Ubiquitin E3 Ligase: Clinical Relevance in Alzheimer's Disease
- (2018) Pravir Kumar et al. JOURNAL OF ALZHEIMERS DISEASE
- Disruption of Brain Redox Homeostasis, Microglia Activation and Neuronal Damage Induced by Intracerebroventricular Administration of S-Adenosylmethionine to Developing Rats
- (2018) Bianca Seminotti et al. MOLECULAR NEUROBIOLOGY
- Coupled brain and urine spectroscopy - in vivo metabolomic characterization of HMG-CoA lyase deficiency in 5 patients
- (2017) Dominique Roland et al. MOLECULAR GENETICS AND METABOLISM
- The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis
- (2017) Keiko Imamura et al. Science Translational Medicine
- Enriched endoplasmic reticulum-mitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice
- (2017) Lihong Zhao et al. Journal of Animal Science and Biotechnology
- Mitochondria-associated membranes as hubs for neurodegeneration
- (2016) Michiel Krols et al. ACTA NEUROPATHOLOGICA
- Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase
- (2016) Haoling Qi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells
- (2016) Ana I. Plácido et al. MOLECULAR NEUROBIOLOGY
- Increased oxidative stress in patients with 3-hydroxy-3-methylglutaric aciduria
- (2015) Mariana dos Santos Mello et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Induction of a Proinflammatory Response in Cortical Astrocytes by the Major Metabolites Accumulating in HMG-CoA Lyase Deficiency: the Role of ERK Signaling Pathway in Cytokine Release
- (2015) Carolina Gonçalves Fernandes et al. MOLECULAR NEUROBIOLOGY
- Intracerebral Glycine Administration Impairs Energy and Redox Homeostasis and Induces Glial Reactivity in Cerebral Cortex of Newborn Rats
- (2015) Alana Pimentel Moura et al. MOLECULAR NEUROBIOLOGY
- NMDA Receptors and Oxidative Stress Induced by the Major Metabolites Accumulating in HMG Lyase Deficiency Mediate Hypophosphorylation of Cytoskeletal Proteins in Brain From Adolescent Rats: Potential Mechanisms Contributing to the Neuropathology of This Disease
- (2015) Carolina Gonçalves Fernandes et al. NEUROTOXICITY RESEARCH
- Titanium Dioxide Nanoparticles Induce Endoplasmic Reticulum Stress-Mediated Autophagic Cell Death via Mitochondria-Associated Endoplasmic Reticulum Membrane Disruption in Normal Lung Cells
- (2015) Kyeong-Nam Yu et al. PLoS One
- Redox homeostasis is compromised in vivo by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency in rat cerebral cortex and liver
- (2013) M. S. da Rosa et al. FREE RADICAL RESEARCH
- In vivo experimental evidence that the major metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency induce oxidative stress in striatum of developing rats: A potential pathophysiological mechanism of striatal damage in this disorder
- (2013) Carolina Gonçalves Fernandes et al. MOLECULAR GENETICS AND METABOLISM
- Novel crosstalk between ERK MAPK and p38 MAPK leads to homocysteine-NMDA receptor-mediated neuronal cell death
- (2012) Ranjana Poddar et al. JOURNAL OF NEUROCHEMISTRY
- An update on the role of mitochondrial α-ketoglutarate dehydrogenase in oxidative stress
- (2012) Anatoly A. Starkov MOLECULAR AND CELLULAR NEUROSCIENCE
- Neonatal Astrocyte Damage Is Sufficient to Trigger Progressive Striatal Degeneration in a Rat Model of Glutaric Acidemia-I
- (2011) Silvia Olivera-Bravo et al. PLoS One
- Neurochemical evidence that glycine induces bioenergetical dysfunction
- (2010) Estela Natacha Brandt Busanello et al. NEUROCHEMISTRY INTERNATIONAL
- Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death
- (2009) Ranjana Poddar et al. JOURNAL OF NEUROCHEMISTRY
- Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau
- (2009) Magdalena Kuszczyk et al. NEUROCHEMISTRY INTERNATIONAL
- Detection of behavioral alterations and learning deficits in mice lacking synaptophysin
- (2009) U. Schmitt et al. NEUROSCIENCE
- Glycine Provokes Lipid Oxidative Damage and Reduces the Antioxidant Defenses in Brain Cortex of Young Rats
- (2008) Guilhian Leipnitz et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: A molecular mechanism leading to hepatic insulin resistance
- (2008) J LIM et al. CELLULAR SIGNALLING
- Methylmalonate inhibits succinate-supported oxygen consumption by interfering with mitochondrial succinate uptake
- (2008) S. R. Mirandola et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Induction of oxidative stress by the metabolites accumulating in 3-methylglutaconic aciduria in cerebral cortex of young rats
- (2008) Guilhian Leipnitz et al. LIFE SCIENCES
- Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome
- (2008) S. H. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence that 3-hydroxy-3-methylglutaric acid promotes lipid and protein oxidative damage and reduces the nonenzymatic antioxidant defenses in rat cerebral cortex
- (2007) Guilhian Leipnitz et al. JOURNAL OF NEUROSCIENCE RESEARCH
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