Estrogen-induced compensatory mechanisms protect IL-10-deficient mice from developing EAE

Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function

(2018) Peter T. Sage et al.   JOURNAL OF IMMUNOLOGY

CXCL9, CXCL10, CXCL11, and their receptor (CXCR3) in neuroinflammation and neurodegeneration

(2018) Olga Koper et al.   Advances in Clinical and Experimental Medicine

Novel feedback loop between M2 macrophages/microglia and regulatory B cells in estrogen-protected EAE mice

(2017) Gil Benedek et al.   JOURNAL OF NEUROIMMUNOLOGY

Estrogen protects both sexes against EAE by promoting common regulatory cell subtypes independent of endogenous estrogen

(2017) Hilary A. Seifert et al.   METABOLIC BRAIN DISEASE

PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome

(2017) Hashem O. Alsaab et al.   Frontiers in Pharmacology

Medium-dose estrogen ameliorates experimental autoimmune encephalomyelitis in ovariectomized mice

(2016) Dariush Haghmorad et al.   Journal of Immunotoxicology

Estrogen induces multiple regulatory B cell subtypes and promotes M2 microglia and neuroprotection during experimental autoimmune encephalomyelitis

(2016) Gil Benedek et al.   JOURNAL OF NEUROIMMUNOLOGY

Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation

(2016) Andrea Pennati et al.   JOURNAL OF NEUROSCIENCE

Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells

(2016) Sarantis Korniotis et al.   Nature Communications

Programmed Death Ligand-1 on Microglia Regulates Th1 Differentiation via Nitric Oxide in Experimental Autoimmune Encephalomyelitis

(2016) Jingxia Hu et al.   Neuroscience Bulletin

IL10 and PD-1 Cooperate to Limit the Activity of Tumor-Specific CD8+ T Cells

(2015) Z. Sun et al.   CANCER RESEARCH

Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy

(2015) Ankit Saxena et al.   CYTOKINE

IL-10 producing B cells partially restore E2-mediated protection against EAE in PD-L1 deficient mice

(2015) Jun Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Treatment with IL-10 producing B cells in combination with E2 ameliorates EAE severity and decreases CNS inflammation in B cell-deficient mice

(2015) Jun Zhang et al.   METABOLIC BRAIN DISEASE

PD-L1hi B cells are critical regulators of humoral immunity

(2015) Adnan R. Khan et al.   Nature Communications

B10 cell regulation of health and disease

(2014) Kathleen M. Candando et al.   IMMUNOLOGICAL REVIEWS

From classic to spontaneous and humanized models of multiple sclerosis: Impact on understanding pathogenesis and drug development

(2014) Avraham Ben-Nun et al.   JOURNAL OF AUTOIMMUNITY

A Novel Mechanism of B Cell–Mediated Immune Suppression through CD73 Expression and Adenosine Production

(2014) Hiroaki Kaku et al.   JOURNAL OF IMMUNOLOGY

Pro-Inflammatory Interferon Gamma Signaling is Directly Associated with Stroke Induced Neurodegeneration

(2014) Hilary A. Seifert et al.   Journal of Neuroimmune Pharmacology

CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system

(2014) Marius Krauthausen et al.   Journal of Neuroinflammation

Expression of Neuronal CXCL10 Induced by Rabies Virus Infection Initiates Infiltration of Inflammatory Cells, Production of Chemokines and Cytokines, and Enhancement of Blood-Brain Barrier Permeability

(2014) Qingqing Chai et al.   JOURNAL OF VIROLOGY

Estrogen Mediates Neuroprotection and Anti-Inflammatory Effects during EAE through ER  Signaling on Astrocytes But Not through ER  Signaling on Astrocytes or Neurons

(2013) R. D. Spence et al.   JOURNAL OF NEUROSCIENCE

Female sex hormones and cytokine secretion in women with multiple sclerosis

(2013) Anastasiya G Trenova et al.   NEUROLOGICAL RESEARCH

Oestrogen treatment of experimental autoimmune encephalomyelitis requires 17β-oestradiol-receptor-positive B cells that up-regulate PD-1 on CD4+ Foxp3+regulatory T cells

(2012) Sheetal Bodhankar et al.   IMMUNOLOGY

Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis

(2012) Jeffrey H Mills et al.   Journal of Neuroinflammation

Clinical course of myelin oligodendrocyte glycoprotein 35–55 induced experimental autoimmune encephalomyelitis is aggravated by glia maturation factor

(2012) Smita Zaheer et al.   NEUROCHEMISTRY INTERNATIONAL

Estrogen-induced protection against experimental autoimmune encephalomyelitis is abrogated in the absence of B cells

(2011) Sheetal Bodhankar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Estrogen Receptor   Signaling in T Lymphocytes Is Required for Estradiol-Mediated Inhibition of Th1 and Th17 Cell Differentiation and Protection against Experimental Autoimmune Encephalomyelitis

(2011) K. Lelu et al.   JOURNAL OF IMMUNOLOGY

Increased expression of chemokine receptor CCR3 and its ligands in ulcerative colitis: the role of colonic epithelial cells in in vitro studies

(2010) P. Manousou et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3+ regulatory T cells implicates compensatory pathways including regulatory B cells

(2010) Sandhya Subramanian et al.   IMMUNOLOGY

Regulatory B Cells (B10 Cells) and Regulatory T Cells Have Independent Roles in Controlling Experimental Autoimmune Encephalomyelitis Initiation and Late-Phase Immunopathogenesis

(2010) T. Matsushita et al.   JOURNAL OF IMMUNOLOGY

CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis

(2008) J. H. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA