标题
The genetic landscape of the human solute carrier (SLC) transporter superfamily
作者
关键词
-
出版物
HUMAN GENETICS
Volume 138, Issue 11-12, Pages 1359-1377
出版商
Springer Science and Business Media LLC
发表日期
2019-11-03
DOI
10.1007/s00439-019-02081-x
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort
- (2019) Kathrin Klein et al. Frontiers in Genetics
- New insights into GluT1 mechanics during glucose transfer
- (2019) Tatiana Galochkina et al. Scientific Reports
- Functional disruption of pyrimidine nucleoside transporter CNT1 results in a novel inborn error of metabolism with high excretion of uridine and cytidine
- (2019) RA Wevers et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Targeted next generation sequencing as a tool for precision medicine
- (2019) Markus Gulilat et al. BMC Medical Genomics
- Structures of human ENT1 in complex with adenosine reuptake inhibitors
- (2019) Nicholas J. Wright et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Benchmarking subcellular localization and variant tolerance predictors on membrane proteins
- (2019) Tommaso Orioli et al. BMC GENOMICS
- How to Consider Rare Genetic Variants in Personalized Drug Therapy
- (2018) Volker M. Lauschke et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- NGS Technologies as a Turning Point in Rare Disease Research , Diagnosis and Treatment
- (2018) Ana Fernandez-Marmiesse et al. CURRENT MEDICINAL CHEMISTRY
- ClinVar Miner: Demonstrating utility of a Web-based tool for viewing and filtering ClinVar data
- (2018) Alex Henrie et al. HUMAN MUTATION
- Comprehensive overview of the pharmacogenetic diversity in Ashkenazi Jews
- (2018) Yitian Zhou et al. JOURNAL OF MEDICAL GENETICS
- OUP accepted manuscript
- (2018) NUCLEIC ACIDS RESEARCH
- Impact of SLC22A1 and CYP3A5 genotypes on imatinib response in chronic myeloid leukemia: A systematic review and meta-analysis
- (2018) Sarah Cargnin et al. PHARMACOLOGICAL RESEARCH
- Pharmacogenetics of toxicity of 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients
- (2018) Karolina Tecza et al. Oncotarget
- Genetic variations in influx transporter gene SLC22A1 are associated with clinical responses to imatinib mesylate among Malaysian chronic myeloid leukaemia patients
- (2018) Siti Maziras Makhtar et al. JOURNAL OF GENETICS
- An optimized prediction framework to assess the functional impact of pharmacogenetic variants
- (2018) Yitian Zhou et al. PHARMACOGENOMICS JOURNAL
- Genetic variability and population diversity of the human SLCO (OATP) transporter family
- (2018) Boyao Zhang et al. PHARMACOLOGICAL RESEARCH
- Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data
- (2018) Yitian Zhou et al. Frontiers in Pharmacology
- Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics
- (2017) María Santos et al. GENETICS IN MEDICINE
- OCT1 pharmacogenetics in pain management: is a clinical application within reach?
- (2017) Mladen V Tzvetkov PHARMACOGENOMICS
- Imatinib-induced ophthalmological side-effects in GIST patients are associated with the variations of EGFR, SLC22A1, SLC22A5 and ABCB1
- (2017) H-B Qiu et al. PHARMACOGENOMICS JOURNAL
- Identification of new SNPs associated with severe toxicity to capecitabine
- (2017) Marta Pellicer et al. PHARMACOLOGICAL RESEARCH
- Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer
- (2017) Britt I. Drögemöller et al. JAMA Oncology
- Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population
- (2017) Liang-Liang Cai et al. Scientific Reports
- Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network
- (2016) WS Bush et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Rare genetic variants in cellular transporters, metabolic enzymes and nuclear receptors can be important determinants of interindividual differences in drug response
- (2016) Mikael Kozyra et al. GENETICS IN MEDICINE
- Analysis of protein-coding genetic variation in 60,706 humans
- (2016) Monkol Lek et al. NATURE
- Equilibrative nucleoside transporters—A review
- (2016) Rebba C. Boswell-Casteel et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- PGRNseq
- (2016) Adam S. Gordon et al. Pharmacogenetics and Genomics
- The global spectrum of protein-coding pharmacogenomic diversity
- (2016) G E B Wright et al. PHARMACOGENOMICS JOURNAL
- Global Carrier Rates of Rare Inherited Disorders Using Population Exome Sequences
- (2016) Kohei Fujikura PLoS One
- Precision Medicine and Rare Genetic Variants
- (2016) Volker M. Lauschke et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- An integrative approach to predicting the functional effects of non-coding and coding sequence variation
- (2015) Hashem A. Shihab et al. BIOINFORMATICS
- LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants: Fig. 1.
- (2015) Mitchell J. Machiela et al. BIOINFORMATICS
- A Call for Systematic Research on Solute Carriers
- (2015) Adrián César-Razquin et al. CELL
- Role of ITPA and SLC28A2 genes in the prediction of anaemia associated with protease inhibitor plus ribavirin and peginterferon in hepatitis C treatment
- (2015) Javier Ampuero et al. JOURNAL OF CLINICAL VIROLOGY
- OCT1 and imatinib transport in CML: is it clinically relevant?
- (2015) D B Watkins et al. LEUKEMIA
- The Phyre2 web portal for protein modeling, prediction and analysis
- (2015) Lawrence A Kelley et al. Nature Protocols
- SLC transporters as therapeutic targets: emerging opportunities
- (2015) Lawrence Lin et al. NATURE REVIEWS DRUG DISCOVERY
- Genetic variation in the human cytochrome P450 supergene family
- (2015) Kohei Fujikura et al. Pharmacogenetics and Genomics
- Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity
- (2015) Claudia Lanvers-Kaminsky et al. PHARMACOGENOMICS
- Genetic variants inSLC22A17 and SLC22A7are associated with anthracycline-induced cardiotoxicity in children
- (2015) Henk Visscher et al. PHARMACOGENOMICS
- SLC15A2 genomic variation is associated with the extraordinary response of sorafenib treatment: whole-genome analysis in patients with hepatocellular carcinoma
- (2015) Yeon-Su Lee et al. Oncotarget
- Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1
- (2015) Tina Seitz et al. Genome Medicine
- Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies
- (2015) C. Dong et al. HUMAN MOLECULAR GENETICS
- Molecular Dynamics Simulations of the Human Glucose Transporter GLUT1
- (2015) Min-Sun Park PLoS One
- DANN: a deep learning approach for annotating the pathogenicity of genetic variants
- (2014) Daniel Quang et al. BIOINFORMATICS
- Does the haplotype Met408-Del420, which was apparently predictive for imatinib efficacy, really exist and how strongly may it affect OCT1 activity?
- (2014) M. V. Tzvetkov et al. BLOOD
- Association of Organic Cation Transporter 1 With Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study
- (2014) Tanja Dujic et al. DIABETES
- Effects of a microRNA binding site polymorphism in SLC19A1 on methotrexate concentrations in Chinese children with acute lymphoblastic leukemia
- (2014) Shu-mei Wang et al. MEDICAL ONCOLOGY
- Crystal structure of the human glucose transporter GLUT1
- (2014) Dong Deng et al. NATURE
- A general framework for estimating the relative pathogenicity of human genetic variants
- (2014) Martin Kircher et al. NATURE GENETICS
- An update on the pharmacogenomics of metformin: progress, problems and potential
- (2014) Jennifer N Todd et al. PHARMACOGENOMICS
- Effect of polymorphisms within methotrexate pathway genes on methotrexate toxicity and plasma levels in adults with hematological malignancies
- (2014) Sujatha Suthandiram et al. PHARMACOGENOMICS
- Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations
- (2014) A Corrigan et al. PHARMACOGENOMICS JOURNAL
- The c.480C>G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia
- (2014) A Di Paolo et al. PHARMACOGENOMICS JOURNAL
- Exonic Variants Associated with Development of Aspirin Exacerbated Respiratory Diseases
- (2014) Seung-Woo Shin et al. PLoS One
- Influences of Organic Cation Transporter Polymorphisms on the Population Pharmacokinetics of Metformin in Healthy Subjects
- (2013) Hwa Yoon et al. AAPS Journal
- Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration
- (2013) Mladen V. Tzvetkov et al. BIOCHEMICAL PHARMACOLOGY
- Identifying Mendelian disease genes with the Variant Effect Scoring Tool
- (2013) Hannah Carter et al. BMC GENOMICS
- SLC Classification: An Update
- (2013) A Schlessinger et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Reduced Renal Clearance of Cefotaxime in Asians with a Low-Frequency Polymorphism of OAT3 (SLC22A8)
- (2013) Sook Wah Yee et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- The SLC4 family of bicarbonate transporters
- (2013) Michael F. Romero et al. MOLECULAR ASPECTS OF MEDICINE
- The SLC22 family with transporters of organic cations, anions and zwitterions
- (2013) Hermann Koepsell MOLECULAR ASPECTS OF MEDICINE
- SLC27 fatty acid transport proteins
- (2013) Courtney M. Anderson et al. MOLECULAR ASPECTS OF MEDICINE
- The SLC2 (GLUT) family of membrane transporters
- (2013) Mike Mueckler et al. MOLECULAR ASPECTS OF MEDICINE
- Crystal structure of a eukaryotic phosphate transporter
- (2013) Bjørn P. Pedersen et al. NATURE
- Rare-disease genetics in the era of next-generation sequencing: discovery to translation
- (2013) Kym M. Boycott et al. NATURE REVIEWS GENETICS
- OCT1 genetic variants influence the pharmacokinetics of morphine in children
- (2013) Tsuyoshi Fukuda et al. PHARMACOGENOMICS
- SLC19A180G allele as a biomarker of methotrexate-related gastrointestinal toxicity in Portuguese rheumatoid arthritis patients
- (2013) Aurea Lima et al. PHARMACOGENOMICS
- SLCO1B1 and SLC19A1 Gene Variants and Irinotecan-Induced Rapid Response and Survival: A Prospective Multicenter Pharmacogenetics Study of Metastatic Colorectal Cancer
- (2013) Liu Huang et al. PLoS One
- GLUT1 deficiency syndrome 2013: Current state of the art
- (2013) Valentina De Giorgis et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Structural advances for the major facilitator superfamily (MFS) transporters
- (2013) Nieng Yan TRENDS IN BIOCHEMICAL SCIENCES
- Genetic variants of organic cation transporter 1 (OCT1) and OCT2 significantly reduce lamivudine uptake
- (2012) Min-Koo Choi et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- The Effect of Novel Promoter Variants in MATE1 and MATE2 on the Pharmacokinetics and Pharmacodynamics of Metformin
- (2012) S L Stocker et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Predicting the Functional, Molecular, and Phenotypic Consequences of Amino Acid Substitutions using Hidden Markov Models
- (2012) Hashem A. Shihab et al. HUMAN MUTATION
- Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection
- (2012) Monika Rau et al. JOURNAL OF HEPATOLOGY
- Cystinuria: an inborn cause of urolithiasis
- (2012) Thomas Eggermann et al. Orphanet Journal of Rare Diseases
- Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients
- (2012) Linda Tarasova et al. Pharmacogenetics and Genomics
- Genetic variation in the SLC19A1 gene and methotrexate toxicity in rheumatoid arthritis patients
- (2012) Petra Bohanec Grabar et al. PHARMACOGENOMICS
- Predicting the Functional Effect of Amino Acid Substitutions and Indels
- (2012) Yongwook Choi et al. PLoS One
- Genetically Polymorphic OCT1: Another Piece in the Puzzle of the Variable Pharmacokinetics and Pharmacodynamics of the Opioidergic Drug Tramadol
- (2011) M V Tzvetkov et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- A Common 5′-UTR Variant in MATE2-K Is Associated With Poor Response to Metformin
- (2011) J H Choi et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Transit Defect of Potassium-Chloride Co-transporter 3 Is a Major Pathogenic Mechanism in Hereditary Motor and Sensory Neuropathy with Agenesis of the Corpus Callosum
- (2011) Adèle Salin-Cantegrel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic Factors Underlying the Risk of Thalidomide-Related Neuropathy in Patients With Multiple Myeloma
- (2011) David C. Johnson et al. JOURNAL OF CLINICAL ONCOLOGY
- Predicting the functional impact of protein mutations: application to cancer genomics
- (2011) Boris Reva et al. NUCLEIC ACIDS RESEARCH
- Role of nucleoside transporters SLC28A2/3 and SLC29A1/2 genetics in ribavirin therapy
- (2011) Alexandra Doehring et al. Pharmacogenetics and Genomics
- Functional Role of the Polymorphic 647 T/C Variant of ENT1 (SLC29A1) and Its Association with Alcohol Withdrawal Seizures
- (2011) Jeong-Hyun Kim et al. PLoS One
- Differential Subcellular Localization of the Splice Variants of the Zinc Transporter ZnT5 Is Dictated by the Different C-Terminal Regions
- (2011) Jared K. Thornton et al. PLoS One
- Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide
- (2010) J Bray et al. BRITISH JOURNAL OF CANCER
- Association analysis of SLC30A8 rs13266634 and rs16889462 polymorphisms with type 2 diabetes mellitus and repaglinide response in Chinese patients
- (2010) Qiong Huang et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Genetic Polymorphisms in Organic Cation Transporter 1 (OCT1) in Chinese and Japanese Populations Exhibit Altered Function
- (2010) L. Chen et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The Solute Carrier Families Have a Remarkably Long Evolutionary History with the Majority of the Human Families Present before Divergence of Bilaterian Species
- (2010) P. J. Hoglund et al. MOLECULAR BIOLOGY AND EVOLUTION
- A method and server for predicting damaging missense mutations
- (2010) Ivan A Adzhubei et al. NATURE METHODS
- Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype
- (2010) Halima Moncrieffe et al. Pharmacogenetics and Genomics
- Effects of OCT1 polymorphisms on the cellular uptake, plasma concentrations and efficacy of the 5-HT3 antagonists tropisetron and ondansetron
- (2010) M V Tzvetkov et al. PHARMACOGENOMICS JOURNAL
- Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++
- (2010) Eugene V. Davydov et al. PLoS Computational Biology
- Association of the Glutamate Transporter Gene SLC1A1 With Atypical Antipsychotics–Induced Obsessive-compulsive Symptoms
- (2009) Jun Soo Kwon et al. ARCHIVES OF GENERAL PSYCHIATRY
- Identification of deleterious mutations within three human genomes
- (2009) S. Chun et al. GENOME RESEARCH
- Five Amino Acids in the Innermost Cavity of the Substrate Binding Cleft of Organic Cation Transporter 1 Interact with Extracellular and Intracellular Corticosterone
- (2009) C. Volk et al. MOLECULAR PHARMACOLOGY
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- The Genetic Structure and History of Africans and African Americans
- (2009) S. A. Tishkoff et al. SCIENCE
- African Genetic Diversity: Implications for Human Demographic History, Modern Human Origins, and Complex Disease Mapping
- (2008) Michael C. Campbell et al. Annual Review of Genomics and Human Genetics
- Genetic Variants of the Organic Cation Transporter 2 Influence the Disposition of Metformin
- (2008) IS Song et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The solute carrier (SLC) complement of the human genome: Phylogenetic classification reveals four major families
- (2008) Robert Fredriksson et al. FEBS LETTERS
- Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients
- (2008) Ross A. Soo et al. LUNG CANCER
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