Cerebrospinal fluid Tau/α-synuclein ratio in Parkinson's disease and degenerative dementias

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Synapse loss in dementias

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Detection of elevated levels of  -synuclein oligomers in CSF from patients with Parkinson disease

(2010) T. Tokuda et al.   NEUROLOGY

EFNS guidelines on disease-specific CSF investigations

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Molecular pathogenesis of Parkinson disease: insights from genetic studies

(2009) Thomas Gasser   EXPERT REVIEWS IN MOLECULAR MEDICINE

α-synuclein antibodies recognize a protein present at lower levels in the CSF of patients with dementia with Lewy bodies

(2009) Clive Ballard et al.   INTERNATIONAL PSYCHOGERIATRICS

Enduring involvement of tau, β-amyloid, α-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism–dementia complex of Guam (ALS/PDC)

(2008) Judith Miklossy et al.   ACTA NEUROPATHOLOGICA

Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease

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CSF α-synuclein levels in dementia with Lewy bodies and Alzheimer's disease

(2008) Moeko Noguchi-Shinohara et al.   BRAIN RESEARCH

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

(2008) Konstanze F Winklhofer et al.   EMBO JOURNAL

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

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Genes associated with Parkinson syndrome

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Neurochemical approaches of cerebrospinal fluid diagnostics in neurodegenerative diseases

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Frontotemporal lobar degeneration with ubiquitinated tau-negative inclusions and additional α-synuclein pathology but also unusual cerebellar ubiquitinated p62-positive, TDP-43-negative inclusions

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Phosphorylation of tau and α-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer’s disease, and in Parkinson’s disease and related α-synucleinopathies

(2008) G. Muntané et al.   NEUROSCIENCE

Cerebrospinal fluid α-synuclein in neurodegenerative disorders—A marker of synapse loss?

(2008) Annika Öhrfelt et al.   NEUROSCIENCE LETTERS

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

(2008) Igor F. Tsigelny et al.   PLoS One