Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin

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Combined MTOR and autophagy inhibition

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(2014) Paola Pellegrini et al.   Autophagy

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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

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Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering

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Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer

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Synergistic Dual-Ligand Doxorubicin Liposomes Improve Targeting and Therapeutic Efficacy of Brain Glioma in Animals

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A pH-responsive α-helical cell penetrating peptide-mediated liposomal delivery system

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Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363

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Doxil® — The first FDA-approved nano-drug: Lessons learned

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Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

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Principles and Current Strategies for Targeting Autophagy for Cancer Treatment

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Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging

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Interfering with pH regulation in tumours as a therapeutic strategy

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The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Cell-Penetrating Peptide Induces Leaky Fusion of Liposomes Containing Late Endosome-Specific Anionic Lipid

(2010) Sung-Tae Yang et al.   BIOPHYSICAL JOURNAL

Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin

(2010) Juan Jiang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

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Efficient Delivery of Payload into Tumor Cells in a Controlled Manner by TAT and Thiolytic Cleavable PEG Co-Modified Liposomes

(2010) Rui Kuai et al.   MOLECULAR PHARMACEUTICS

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases

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Therapeutic Nanoparticles for Drug Delivery in Cancer

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