The basal chorionic trophoblast cell layer: An emerging coordinator of placenta development

A Grhl2-dependent gene network controls trophoblast branching morphogenesis

(2015) K. Walentin et al.   DEVELOPMENT

A Grainyhead-Like 2/Ovo-Like 2 Pathway Regulates Renal Epithelial Barrier Function and Lumen Expansion

(2015) A. Aue et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer

(2015) Yingjun Quan et al.   Journal of Cancer

Essential role of the ERK/MAPK pathway in blood-placental barrier formation

(2014) Valérie Nadeau et al.   DEVELOPMENT

Adaptive mechanisms controlling uterine spiral artery remodeling during the establishment of pregnancy

(2014) Michael J. Soares et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

A Matriptase-Prostasin Reciprocal Zymogen Activation Complex with Unique Features

(2013) Stine Friis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ly6e expression is restricted to syncytiotrophoblast cells of the mouse placenta

(2013) M. Hughes et al.   PLACENTA

Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium

(2013) Xia Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Positive Feedback Loop Involving Gcm1 and Fzd5 Directs Chorionic Branching Morphogenesis in the Placenta

(2013) Jinhua Lu et al.   PLOS BIOLOGY

The Transcription Factors Grainyhead-like 2 and NK2-Homeobox 1 Form a Regulatory Loop That Coordinates Lung Epithelial Cell Morphogenesis and Differentiation

(2012) Saaket Varma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness

(2012) Takashi Baba et al.   JOURNAL OF PATHOLOGY

Diversity of Matriptase Expression Level and Function in Breast Cancer

(2012) Arkadiusz Welman et al.   PLoS One

Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency–Associated Developmental Defects by Preventing Matriptase Activation

(2012) Roman Szabo et al.   PLoS Genetics

Membrane-Bound Serine Protease Inhibitor HAI-1 Is Required for Maintenance of Intestinal Epithelial Integrity

(2011) Makiko Kawaguchi et al.   AMERICAN JOURNAL OF PATHOLOGY

Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development

(2011) Erica D. Watson et al.   DEVELOPMENTAL DYNAMICS

Grhl2 deficiency impairs otic development and hearing ability in a zebrafish model of the progressive dominant hearing loss DFNA28

(2011) Yanchao Han et al.   HUMAN MOLECULAR GENETICS

GCM1 Regulation of the Expression of Syncytin 2 and Its Cognate Receptor MFSD2A in Human Placenta1

(2010) Ching-Yeu Liang et al.   BIOLOGY OF REPRODUCTION

The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex

(2010) M. Werth et al.   DEVELOPMENT

Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo

(2010) Eric Camerer et al.   DEVELOPMENTAL CELL

A Cdh1HA knock-in allele rescues the Cdh1−/− phenotype but shows essential Cdh1 function during placentation

(2010) Marc P. Stemmler et al.   DEVELOPMENTAL DYNAMICS

Regulation of the Matriptase-Prostasin Cell Surface Proteolytic Cascade by Hepatocyte Growth Factor Activator Inhibitor-1 during Epidermal Differentiation

(2010) Ya-Wen Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Laminin-332 cleavage by matriptase alters motility parameters of prostate cancer cells

(2010) Manisha Tripathi et al.   PROSTATE

Basement Membranes: Cell Scaffoldings and Signaling Platforms

(2010) P. D. Yurchenco   Cold Spring Harbor Perspectives in Biology

Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway

(2009) Karin List et al.   AMERICAN JOURNAL OF PATHOLOGY

Map2k1 and Map2k2 genes contribute to the normal development of syncytiotrophoblasts during placentation

(2009) V. Nadeau et al.   DEVELOPMENT

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice

(2009) R. Szabo et al.   DEVELOPMENT

Camostat Attenuates Airway Epithelial Sodium Channel Function in Vivo through the Inhibition of a Channel-Activating Protease

(2009) K. Coote et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene

(2009) A. Dupressoir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defect of Hepatocyte Growth Factor Activator Inhibitor Type 1/Serine Protease Inhibitor, Kunitz Type 1 (Hai-1/Spint1) Leads to Ichthyosis-Like Condition and Abnormal Hair Development in Mice

(2008) Koki Nagaike et al.   AMERICAN JOURNAL OF PATHOLOGY

Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

(2008) D. G. Simmons et al.   DEVELOPMENT

Potent Inhibition and Global Co-localization Implicate the Transmembrane Kunitz-type Serine Protease Inhibitor Hepatocyte Growth Factor Activator Inhibitor-2 in the Regulation of Epithelial Matriptase Activity

(2008) Roman Szabo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis

(2008) M. Narasimha et al.   JOURNAL OF CELL SCIENCE

Type II transmembrane serine proteases in development and disease

(2007) R SZABO et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY