Elaborating Complex Heteroaryl-Containing Cycles via Enantioselective Palladium-Catalyzed Cycloadditions
出版年份 2019 全文链接
标题
Elaborating Complex Heteroaryl-Containing Cycles via Enantioselective Palladium-Catalyzed Cycloadditions
作者
关键词
-
出版物
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 58, Issue 42, Pages 15154-15158
出版商
Wiley
发表日期
2019-09-05
DOI
10.1002/anie.201910061
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Catalytic Asymmetric Synthesis of α-Arylpyrrolidines and Benzo-fused Nitrogen Heterocycles
- (2019) Xi-Jie Dai et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Palladium-Catalyzed Asymmetric C(sp3 )−H Allylation of 2-Alkylpyridines
- (2018) Ryo Murakami et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Deprotonation Approach to the Unprecedented Amino-Trimethylenemethane Chemistry: Regio-, Diastereo-, and Enantioselective Synthesis of Complex Amino Cycles
- (2018) Barry M. Trost et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Organic synthesis provides opportunities to transform drug discovery
- (2018) David C. Blakemore et al. Nature Chemistry
- Catalytic enantioselective Minisci-type addition to heteroarenes
- (2018) Rupert S. J. Proctor et al. SCIENCE
- Enantioselective Palladium-Catalyzed [3+2] Cycloaddition of Trimethylenemethane and Fluorinated Ketones
- (2018) Barry M. Trost et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Iron–Nickel Dual-Catalysis: A New Engine for Olefin Functionalization and the Formation of Quaternary Centers
- (2018) Samantha A. Green et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Building C(sp3)-rich complexity by combining cycloaddition and C–C cross-coupling reactions
- (2018) Tie–Gen Chen et al. NATURE
- Late-Stage C–H Alkylation of Heterocycles and 1,4-Quinones via Oxidative Homolysis of 1,4-Dihydropyridines
- (2017) Álvaro Gutiérrez-Bonet et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Metal-free C–H alkylation of heteroarenes with alkyltrifluoroborates: a general protocol for 1°, 2° and 3° alkylation
- (2017) Jennifer K. Matsui et al. Chemical Science
- Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates
- (2017) Philipp Schäfer et al. Nature Communications
- Nickel-Catalyzed Asymmetric Reductive Cross-Coupling between Heteroaryl Iodides and α-Chloronitriles
- (2015) Nathaniel T. Kadunce et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Alcohols as alkylating agents in heteroarene C–H functionalization
- (2015) Jian Jin et al. NATURE
- The direct arylation of allylic sp3 C–H bonds via organic and photoredox catalysis
- (2015) James D. Cuthbertson et al. NATURE
- A General Palladium-Catalyzed Method for Alkylation of Heteroarenes Using Secondary and Tertiary Alkyl Halides
- (2014) Xiaojin Wu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct α-Arylation of Ethers through the Combination of Photoredox-Mediated CH Functionalization and the Minisci Reaction
- (2014) Jian Jin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Rings in Drugs
- (2014) Richard D. Taylor et al. JOURNAL OF MEDICINAL CHEMISTRY
- Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
- (2014) Edon Vitaku et al. JOURNAL OF MEDICINAL CHEMISTRY
- Palladium-Catalyzed C–H Activation/Cross-Coupling of Pyridine N-Oxides with Nonactivated Secondary Alkyl Bromides
- (2013) Bin Xiao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Radical-Based Regioselective C–H Functionalization of Electron-Deficient Heteroarenes: Scope, Tunability, and Predictability
- (2013) Fionn O’Hara et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Practical and innate carbon–hydrogen functionalization of heterocycles
- (2012) Yuta Fujiwara et al. NATURE
- 3-Pyridyl Substituted Aliphatic Cycles as CYP11B2 Inhibitors: Aromaticity Abolishment of the Core Significantly Increased Selectivity over CYP1A2
- (2012) Lina Yin et al. PLoS One
- The developability of heteroaromatic and heteroaliphatic rings – do some have a better pedigree as potential drug molecules than others?
- (2012) Timothy J. Ritchie et al. MedChemComm
- The Significance of Chirality in Drug Design and Development
- (2011) W. H. Brooks et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
- (2011) Stephen D. Roughley et al. JOURNAL OF MEDICINAL CHEMISTRY
- Palladium-Catalyzed Asymmetric Allylic Alkylations of Polynitrogen-Containing Aromatic Heterocycles
- (2011) Barry M. Trost et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A New Cytotoxicβ-Carboline Alkaloid fromGalianthe thalictroides
- (2011) Patrícia Figueiredo et al. PLANTA MEDICA
- Minisci reactions: Versatile CH-functionalizations for medicinal chemists
- (2011) Matthew A. J. Duncton MedChemComm
- Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
- (2009) Frank Lovering et al. JOURNAL OF MEDICINAL CHEMISTRY
- Strategy for Employing Unstabilized Nucleophiles in Palladium-Catalyzed Asymmetric Allylic Alkylations
- (2008) Barry M. Trost et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started