Synergistic N-Heterocyclic Carbene/Palladium-Catalyzed Umpolung 1,4-Addition of Aryl Iodides to Enals

Synergistic N‐Heterocyclic Carbene/Palladium‐Catalyzed Aldehyde Acylation of Allylic Amines

(2019) Nagisa Ohnishi et al.   Asian Journal of Organic Chemistry

Highly Regio- and Stereodivergent Access to 1,2-Amino Alcohols or 1,4-Fluoro Alcohols by NHC-Catalyzed Ring Opening of Epoxy enals

(2018) Si Bei Poh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Free Decarboxylative Propargylic Substitution/Cyclization with either Azolium Enolates or Acyl Anions

(2018) Shenci Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic N-Heterocyclic Carbene/Palladium-Catalyzed Reactions of Aldehyde Acyl Anions with either Diarylmethyl or Allylic Carbonates

(2018) Shigeo Yasuda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective α-Benzylation of Acyclic Esters Using π-Extended Electrophiles.

(2018) Kevin Schwarz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Traversing Steric Limitations by Cooperative Lewis Base/Palladium Catalysis: An Enantioselective Synthesis of α-Branched Esters Using 2-Substituted Allyl Electrophiles

(2018) Kevin J. Schwarz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective N-Heterocyclic Carbene Catalysis via the Dienyl Acyl Azolium

(2018) Rachel M. Gillard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Access to Enantioenriched Organosilanes from Enals and β-Silyl Enones: Carbene Organocatalysis

(2018) Yuxia Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Regiocontrollable Reductive Heck Reaction of Unactivated Aliphatic Alkenes

(2018) Chengdong Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective [5 + 2] Annulations through Cooperative N-Heterocyclic Carbene (NHC) Organocatalysis and Palladium Catalysis

(2018) Santanu Singha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lewis Base/Copper Cooperatively Catalyzed Asymmetric α-Amination of Esters with Diaziridinone

(2018) Jin Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel(0)-Catalyzed Linear-Selective Hydroarylation of Unactivated Alkenes and Styrenes with Aryl Boronic Acids

(2018) Honggui Lv et al.   Chemical Science

α-Quaternary Chiral Aldehydes from Styrenes, Allylic Alcohols, and Syngas via Multi-catalyst Relay Catalysis

(2018) Jing Meng et al.   Chem

Dehydrative Allylation between Aldehydes and Allylic Alcohols through Synergistic N-Heterocyclic Carbene/Palladium Catalysis

(2018) Hiroki Haruki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photochemical generation of radicals from alkyl electrophiles using a nucleophilic organic catalyst

(2018) Bertrand Schweitzer-Chaput et al.   Nature Chemistry

New phenylpropanoid-substituted flavan-3-ols and flavonols from the leaves of Uncaria rhynchophylla

(2017) Ruxin Li et al.   FITOTERAPIA

Mechanistic Studies on a Cooperative NHC Organocatalysis/Palladium Catalysis System: Uncovering Significant Lessons for Mixed Chiral Pd(NHC)(PR3) Catalyst Design

(2017) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-light excitation of iminium ions enables the enantioselective catalytic β-alkylation of enals

(2017) Mattia Silvi et al.   Nature Chemistry

N-Heterocyclic Carbene Catalysis via the α,β-Unsaturated Acyl Azolium

(2017) Changhe Zhang et al.   ACS Catalysis

Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations

(2016) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Allylic C–H Alkylation of Terminal Olefins with Pyrazol-5-ones Enabled by Cooperative Catalysis of Palladium Complex and Brønsted Acid

(2016) Hua-Chen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Uniting C1-Ammonium Enolates and Transition Metal Electrophiles via Cooperative Catalysis: The Direct Asymmetric α-Allylation of Aryl Acetic Acid Esters

(2016) Kevin J. Schwarz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development and Analysis of a Pd(0)-Catalyzed Enantioselective 1,1-Diarylation of Acrylates Enabled by Chiral Anion Phase Transfer

(2016) Eiji Yamamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Free Nickel-Catalysed 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Carbonyl Compounds

(2015) Wen Chen et al.   ADVANCED SYNTHESIS & CATALYSIS

Chiral Primary Amine/Palladium Dual Catalysis for Asymmetric Allylic Alkylation of β-Ketocarbonyl Compounds with Allylic Alcohols

(2015) Han Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Spirocyclohexadienones by NHC-Catalyzed Formal [3+3] Annulation Reaction of Enals

(2015) Santhivardhana Reddy Yetra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes

(2015) Tobias Sandmeier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

Tutorial on Oxidative Addition

(2015) Jay A. Labinger   ORGANOMETALLICS

N-Heterocyclic-Carbene-Catalyzed Synthesis of 2-Aryl Indoles

(2014) M. Todd Hovey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dual-function Pd/NHC catalysis: tandem allylation–isomerization–conjugate addition that allows access to pyrroles, thiophenes and furans

(2014) Yaguang Bai et al.   CHEMICAL COMMUNICATIONS

A highly efficient dual catalysis approach for C-glycosylation: addition of (o-azaaryl)carboxaldehyde to glycals

(2014) Yaguang Bai et al.   CHEMICAL COMMUNICATIONS

Direct β-Alkylation of Aldehydes via Photoredox Organocatalysis

(2014) Jack A. Terrett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

N-Heterocyclic Carbene-Catalyzed Chemoselective Cross-Aza-Benzoin Reaction of Enals with Isatin-Derived Ketimines: Access to Chiral Quaternary Aminooxindoles

(2014) Jianfeng Xu et al.   ORGANIC LETTERS

A cooperative N-heterocyclic carbene/palladium catalysis system

(2014) Kun Liu et al.   Chemical Science

Asymmetric Synthesis of Pyrroloindolones by N-Heterocyclic Carbene Catalyzed [2+3] Annulation of α-Chloroaldehydes with Nitrovinylindoles

(2013) Qijian Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Catalysis through Noncovalent Interactions

(2013) Weijun Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective N-Heterocyclic Carbene Catalyzed Aza-Benzoin Reaction of Enals with Activated Ketimines

(2013) Li-Hui Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective N-Heterocyclic Carbene Catalyzed Annulation Reactions with Imidazolidinones

(2013) Elizabeth O'Bryan McCusker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Palladium/Chiral Amine Co-catalyzed Enantioselective Dynamic Cascade Reaction: Synthesis of Polysubstituted Carbocycles with a Quaternary Carbon Stereocenter

(2013) Guangning Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Tandem Isomerization/Prins Strategy: Iridium(III)/Brønsted Acid Cooperative Catalysis

(2013) Vince M. Lombardo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Dual Lewis Base Activation Strategy for Enantioselective Carbene-Catalyzed Annulations

(2013) Javier Izquierdo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Asymmetric Allylic Alkylation of Pyrazol-5-ones with Allylic Alcohols: The Role of the Chiral Phosphoric Acid in C–O Bond Cleavage and Stereocontrol

(2013) Zhong-Lin Tao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst

(2013) Ki Po Jang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Carbon activation of saturated carboxylic esters through N-heterocyclic carbene organocatalysis

(2013) Zhenqian Fu et al.   Nature Chemistry

Enantio- and Diastereodivergent Dual Catalysis:  -Allylation of Branched Aldehydes

(2013) S. Krautwald et al.   SCIENCE

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

(2012) Julien Dugal-Tessier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Relay Catalysis Using a Rhodium Complex/Chiral Brønsted Acid Binary System: Enantioselective Reduction of a Carbonyl Ylide as the Reactive Intermediate

(2012) Masahiro Terada et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combining transition metal catalysis and organocatalysis – an update

(2012) Zhenting Du et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Catalyzed Homoenolate Additions with N-Aryl Ketimines as Electrophiles: Efficient Synthesis of Spirocyclic γ-Lactam Oxindoles

(2012) Bo Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Hybrid Metal/Organo Relay Catalysis Enables Enynes To Be Latent Dienes for Asymmetric Diels–Alder Reaction

(2012) Zhi-Yong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Reductive Conjugate Addition to Enones via Allylnickel Intermediates

(2012) Ruja Shrestha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Cyclizations of Conjugated Trienes with Low Catalyst Loadings: A Robust Chiral N-Heterocyclic Carbene Enabled by Acetic Acid Cocatalyst

(2012) Guansai Liu et al.   ORGANIC LETTERS

Highly Enantioselective Addition of Enals to Isatin-Derived Ketimines Catalyzed by N-Heterocyclic Carbenes: Synthesis of Spirocyclic γ-Lactams

(2012) Hui Lv et al.   ORGANIC LETTERS

Synergistic catalysis: A powerful synthetic strategy for new reaction development

(2012) Anna E. Allen et al.   Chemical Science

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

(2011) Daniel T. Cohen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Stetter Reactions of Enals and Modified Chalcones Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins

(2011) Li-Hui Sun et al.   CHEMICAL COMMUNICATIONS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union

(2011) George C. Fortman et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Intermolecular Stetter Reaction of Enals with Nitroalkenes: Enhancement of Catalytic Efficiency through Bifunctional Additives

(2011) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Unifying Metal and Brønsted Acid Catalysis-Concepts, Mechanisms, and Classifications

(2010) Magnus Rueping et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from  , -unsaturated aldehydes for enantioselective Diels-Alder reactions

(2010) J. Kaeobamrung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly enantioselective intramolecular Michael reactions by d-camphor-derived triazolium salts

(2009) Yi Li et al.   CHEMICAL COMMUNICATIONS

Combining transition metal catalysis and organocatalysis: a broad new concept for catalysis

(2009) Zhihui Shao et al.   CHEMICAL SOCIETY REVIEWS

Consecutive Intramolecular Hydroamination/Asymmetric Transfer Hydrogenation under Relay Catalysis of an Achiral Gold Complex/Chiral Brønsted Acid Binary System

(2009) Zhi-Yong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbonyl Umpolung Reactivity of Enals: NHC-Catalyzed Synthesis of Aldol Products via Epoxide Ring Opening

(2009) Lal Yadav et al.   SYNLETT

Diastereoselective Synthesis of Trifluoromethylated γ-Butyrolactonesvia N-Heterocyclic Carbene-Catalyzed Conjugated Umpolung of α,β-Unsaturated Aldehydes

(2008) Keiichi Hirano et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereoselective Synthesis of γ-ButyrolactonesviaOrganocatalytic Annulations of Enals and Keto Esters

(2008) Yi Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Lewis Base Catalysis in Organic Synthesis

(2008) Scott E. Denmark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings

(2008) Michael Rommel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative Catalysis with Chiral Brønsted Acid-Rh2(OAc)4: Highly Enantioselective Three-Component Reactions of Diazo Compounds with Alcohols and Imines

(2008) Wenhao Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Relay Catalysis by a Metal-Complex/Brønsted Acid Binary System in a Tandem Isomerization/Carbon−Carbon Bond Forming Sequence

(2008) Keiichi Sorimachi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective, NHC-Catalyzed Bicyclo-β-Lactam Formation via Direct Annulations of Enals and UnsaturatedN-Sulfonyl Ketimines

(2007) Ming He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY