Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing
出版年份 2019 全文链接
标题
Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing
作者
关键词
-
出版物
Science Advances
Volume 5, Issue 8, Pages eaax0801
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2019-08-29
DOI
10.1126/sciadv.aax0801
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Bioconjugated oligonucleotides: recent developments and therapeutic applications
- (2019) sebastien benizri et al. BIOCONJUGATE CHEMISTRY
- Thiol-Epoxy “Click” Chemistry to Engineer Cytocompatible PEG-based Hydrogel for siRNA-Mediated Osteogenesis of hMSCs
- (2018) Cong Truc Huynh et al. ACS Applied Materials & Interfaces
- RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects
- (2018) Minh K. Nguyen et al. Acta Biomaterialia
- Engineering Osteoinductive Biomaterials by Bioinspired Synthesis of Apatite Coatings on Collagen Hydrogels with Varied Pore Microarchitectures
- (2017) Jacqueline L. Harding et al. TISSUE ENGINEERING PART A
- Photocrosslinkable, biodegradable hydrogels with controlled cell adhesivity for prolonged siRNA delivery to hMSCs to enhance their osteogenic differentiation
- (2017) Minh Khanh Nguyen et al. Journal of Materials Chemistry B
- Cytocompatible Catalyst-Free Photodegradable Hydrogels for Light-Mediated RNA Release To Induce hMSC Osteogenesis
- (2017) Cong Truc Huynh et al. ACS Biomaterials-Science & Engineering
- Cytocompatible Catalyst-Free Photodegradable Hydrogels for Light-Mediated RNA Release To Induce hMSC Osteogenesis
- (2017) Cong Truc Huynh et al. ACS Biomaterials Science & Engineering
- Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment
- (2017) Lan Huong Nguyen et al. Scientific Reports
- Sulfamethazine-based pH-sensitive hydrogels with potential application for transcatheter arterial chemoembolization therapy
- (2016) Jae Seung Lym et al. Acta Biomaterialia
- Current preclinical small interfering RNA (siRNA)-based conjugate systems for RNA therapeutics
- (2016) Soo Hyeon Lee et al. ADVANCED DRUG DELIVERY REVIEWS
- Injectable, Guest–Host Assembled Polyethylenimine Hydrogel for siRNA Delivery
- (2016) Leo L. Wang et al. BIOMACROMOLECULES
- Sustained delivery of siRNA/PEI complex from in situ forming hydrogels potently inhibits the proliferation of gastric cancer
- (2016) Hao Peng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Light-triggered RNA release and induction of hMSC osteogenesis via photodegradable, dual-crosslinked hydrogels
- (2016) Cong Truc Huynh et al. Nanomedicine
- Intraarterial gelation of injectable cationic pH/temperature-sensitive radiopaque embolic hydrogels in a rabbit hepatic tumor model and their potential application for liver cancer treatment
- (2016) Cong Truc Huynh et al. RSC Advances
- Local Delivery of PHD2 siRNA from ROS-Degradable Scaffolds to Promote Diabetic Wound Healing
- (2016) John R. Martin et al. Advanced Healthcare Materials
- Surface-mediated delivery of siRNA from fibrin hydrogels for knockdown of the BMP-2 binding antagonist noggin
- (2015) Christine J. Kowalczewski et al. Acta Biomaterialia
- Tissue engineering and microRNAs: future perspectives in regenerative medicine
- (2015) Manuele Gori et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and antagomiRs to human mesenchymal stem cells
- (2015) Irene Mencía Castaño et al. JOURNAL OF CONTROLLED RELEASE
- Chemically modified RNA activated matrices enhance bone regeneration
- (2015) Satheesh Elangovan et al. JOURNAL OF CONTROLLED RELEASE
- Photocleavable Hydrogels for Light-Triggered siRNA Release
- (2015) Cong Truc Huynh et al. Advanced Healthcare Materials
- Delivery systems for siRNA drug development in cancer therapy
- (2015) Cong-fei Xu et al. Asian Journal of Pharmaceutical Sciences
- Sustained localized presentation of RNA interfering molecules from in situ forming hydrogels to guide stem cell osteogenic differentiation
- (2014) Minh K. Nguyen et al. BIOMATERIALS
- Targetable micelleplex hydrogel for long-term, effective, and systemic siRNA delivery
- (2014) Young-Min Kim et al. BIOMATERIALS
- Recent developments in the co-delivery of siRNA and small molecule anticancer drugs for cancer treatment
- (2014) Manju Saraswathy et al. Materials Today
- Nanotoxicity: a key obstacle to clinical translation of siRNA-based nanomedicine
- (2014) Hui Yi Xue et al. Nanomedicine
- Nanoparticle-Mediated Systemic Delivery of siRNA for Treatment of Cancers and Viral Infections
- (2014) Mohamed Shehata Draz et al. Theranostics
- Hydrogel Doped with Nanoparticles for Local Sustained Release of siRNA in Breast Cancer
- (2014) Nathaly Segovia et al. Advanced Healthcare Materials
- Tunable Delivery of siRNA from a Biodegradable Scaffold to Promote Angiogenesis In Vivo
- (2013) Christopher E. Nelson et al. ADVANCED MATERIALS
- Differential Polymer Structure Tunes Mechanism of Cellular Uptake and Transfection Routes of Poly(β-amino ester) Polyplexes in Human Breast Cancer Cells
- (2013) Jayoung Kim et al. BIOCONJUGATE CHEMISTRY
- Reducible Hyaluronic Acid–siRNA Conjugate for Target Specific Gene Silencing
- (2013) Kitae Park et al. BIOCONJUGATE CHEMISTRY
- Protein-resistant, reductively dissociable polyplexes for in vivo systemic delivery and tumor-targeting of siRNA
- (2013) Jee Seon Kim et al. BIOMATERIALS
- Chitosan/siRNA Nanoparticles Encapsulated in PLGA Nanofibers for siRNA Delivery
- (2012) Menglin Chen et al. ACS Nano
- Injectable Polyplex Hydrogel for Localized and Long-Term Delivery of siRNA
- (2012) Young-Min Kim et al. ACS Nano
- Functionalized, biodegradable hydrogels for control over sustained and localized siRNA delivery to incorporated and surrounding cells
- (2012) Khanh Nguyen et al. Acta Biomaterialia
- A Highly Entangled Polymeric Nanoconstruct Assembled by siRNA and its Reduction-Triggered siRNA Release for Gene Silencing
- (2012) Ran Namgung et al. Small
- Chitosan hydrogel for localized gene silencing
- (2011) Hee Dong Han et al. CANCER BIOLOGY & THERAPY
- Localized, Targeted, and Sustained siRNA Delivery
- (2011) Melissa D. Krebs et al. CHEMISTRY-A EUROPEAN JOURNAL
- Smart siRNA delivery systems based on polymeric nanoassemblies and nanoparticles
- (2010) Atsushi Tamura et al. Nanomedicine
- Localized and Sustained Delivery of Silencing RNA from Macroscopic Biopolymer Hydrogels
- (2009) Melissa D. Krebs et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Surface-Modified and Internally Cationic Polyamidoamine Dendrimers for Efficient siRNA Delivery
- (2008) Mahesh L. Patil et al. BIOCONJUGATE CHEMISTRY
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