Tunable Delivery of siRNA from a Biodegradable Scaffold to Promote Angiogenesis In Vivo

Matrix Metalloproteinase Responsive, Proximity-Activated Polymeric Nanoparticles for siRNA Delivery

(2013) Hongmei Li et al.   ADVANCED FUNCTIONAL MATERIALS

An injectable cell penetrable nano-polyplex hydrogel for localized siRNA delivery

(2013) Young-Min Kim et al.   BIOMATERIALS

Effective Delivery of siRNA into Cancer Cells and Tumors Using Well-Defined Biodegradable Cationic Star Polymers

(2013) Cyrille Boyer et al.   MOLECULAR PHARMACEUTICS

First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

(2013) Josep Tabernero et al.   Cancer Discovery

Chitosan/siRNA Nanoparticles Encapsulated in PLGA Nanofibers for siRNA Delivery

(2012) Menglin Chen et al.   ACS Nano

Injectable Polyplex Hydrogel for Localized and Long-Term Delivery of siRNA

(2012) Young-Min Kim et al.   ACS Nano

Intra-articular controlled release of anti-inflammatory siRNA with biodegradable polymer microparticles ameliorates temporomandibular joint inflammation

(2012) Paschalia M. Mountziaris et al.   Acta Biomaterialia

Functionalized, biodegradable hydrogels for control over sustained and localized siRNA delivery to incorporated and surrounding cells

(2012) Khanh Nguyen et al.   Acta Biomaterialia

Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation

(2011) Tomoya Manaka et al.   BIOMATERIALS

Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications

(2011) Pim-on Rujitanaroj et al.   BIOMATERIALS

Sustained local delivery of siRNA from an injectable scaffold

(2011) Christopher E. Nelson et al.   BIOMATERIALS

Chitosan hydrogel for localized gene silencing

(2011) Hee Dong Han et al.   CANCER BIOLOGY & THERAPY

Injectable polyurethane composite scaffolds delay wound contraction and support cellular infiltration and remodeling in rat excisional wounds

(2011) Elizabeth J. Adolph et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Progress Toward In Vivo Use of siRNAs-II

(2011) Garrett R Rettig et al.   MOLECULAR THERAPY

Controlled Release of IGF-1 and HGF from a Biodegradable Polyurethane Scaffold

(2011) Devin M. Nelson et al.   PHARMACEUTICAL RESEARCH

Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure

(2011) Meredith Wetterau et al.   WOUND REPAIR AND REGENERATION

RNAi-Based Treatment for Neovascular Age-Related Macular Degeneration by Sirna-027

(2010) Peter K. Kaiser et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

RNA Interference Therapy in Lung Transplant Patients Infected with Respiratory Syncytial Virus

(2010) Martin R. Zamora et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of Smad3 Expression in Radiation-Induced Fibrosis Using a Novel Method for Topical Transcutaneous Gene Therapy

(2010) Judy W. Lee et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

pH-Responsive Polymeric Micelle Carriers for siRNA Drugs

(2010) A. J. Convertine et al.   BIOMACROMOLECULES

Characterization of the degradation mechanisms of lysine-derived aliphatic poly(ester urethane) scaffolds

(2010) Andrea E. Hafeman et al.   BIOMATERIALS

Strength of Antimicrobial Bone Cement Decreases with Increased Poragen Fraction

(2010) Matt Nugent et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Bioartificial matrices for therapeutic vascularization

(2010) Edward A. Phelps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved diabetic wound healing through topical silencing of p53 is associated with augmented vasculogenic mediators

(2010) Phuong D. Nguyen et al.   WOUND REPAIR AND REGENERATION

Snail1 Down-Regulation using Small Interfering RNA Complexes Delivered through Collagen Scaffolds

(2009) Rosa Viñas-Castells et al.   BIOCONJUGATE CHEMISTRY

The effect of the local delivery of platelet-derived growth factor from reactive two-component polyurethane scaffolds on the healing in rat skin excisional wounds

(2009) Bing Li et al.   BIOMATERIALS

The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora

(2009) Bing Li et al.   BIOMATERIALS

Bioapplications of RAFT Polymerization

(2009) Cyrille Boyer et al.   CHEMICAL REVIEWS

TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation

(2009) A. Larange et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice

(2009) Xing Shen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Localized and Sustained Delivery of Silencing RNA from Macroscopic Biopolymer Hydrogels

(2009) Melissa D. Krebs et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular Delivery of a Proapoptotic Peptide via Conjugation to a RAFT Synthesized Endosomolytic Polymer

(2009) Craig L. Duvall et al.   MOLECULAR PHARMACEUTICS

First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder

(2009) Sancy A Leachman et al.   MOLECULAR THERAPY

Vascular Growth in Ischemic Limbs: A Review of Mechanisms and Possible Therapeutic Stimulation

(2008) V. van Weel et al.   ANNALS OF VASCULAR SURGERY

3D imaging of tissue integration with porous biomaterials

(2008) Robert E. Guldberg et al.   BIOMATERIALS

BARRIERS TO SUCCESSFUL DELIVERY OF SHORT INTERFERING RNA AFTER SYSTEMIC ADMINISTRATION

(2008) Paul J White   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Development of a novel endosomolytic diblock copolymer for siRNA delivery

(2008) Anthony J. Convertine et al.   JOURNAL OF CONTROLLED RELEASE

Injectable Biodegradable Polyurethane Scaffolds with Release of Platelet-derived Growth Factor for Tissue Repair and Regeneration

(2008) Andrea E. Hafeman et al.   PHARMACEUTICAL RESEARCH

The Role of Osteopontin in Recovery from Hind Limb Ischemia

(2007) Craig L. Duvall et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY