标题
NK Cell Metabolism and Tumor Microenvironment
作者
关键词
-
出版物
Frontiers in Immunology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-09-24
DOI
10.3389/fimmu.2019.02278
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Overcoming Resistance to Natural Killer Cell Based Immunotherapies for Solid Tumors
- (2019) Gaurav Nayyar et al. Frontiers in Oncology
- NK cell metabolism
- (2019) Clair M. Gardiner JOURNAL OF LEUKOCYTE BIOLOGY
- Interleukin-18 up-regulates amino acid transporters and facilitates amino acid–induced mTORC1 activation in natural killer cells
- (2019) Saeedah Musaed Almutairi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration
- (2019) D. Rossin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Targeting natural killer cells in solid tumors
- (2019) Guillaume Habif et al. Cellular & Molecular Immunology
- The role of cytokines in the regulation of NK cells in the tumor environment
- (2019) Gordana M. Konjević et al. CYTOKINE
- The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc
- (2019) Han Dong et al. NATURE IMMUNOLOGY
- NK cells to cure cancer
- (2019) Clara Di Vito et al. SEMINARS IN IMMUNOLOGY
- Competition for nutrients and its role in controlling immune responses
- (2019) Nidhi Kedia-Mehta et al. Nature Communications
- NKG2A is a NK cell exhaustion checkpoint for HCV persistence
- (2019) Chao Zhang et al. Nature Communications
- Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy
- (2018) Tina Cascone et al. Cell Metabolism
- Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression
- (2018) Jingjing Cong et al. Cell Metabolism
- Nitric Oxide Production by Myeloid-Derived Suppressor Cells Plays a Role in Impairing Fc Receptor–Mediated Natural Killer Cell Function
- (2018) Andrew Stiff et al. CLINICAL CANCER RESEARCH
- Canonical TGF-β Signaling Pathway Represses Human NK Cell Metabolism
- (2018) Vanessa Zaiatz-Bittencourt et al. JOURNAL OF IMMUNOLOGY
- The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity
- (2018) Wilson Castro et al. NATURE IMMUNOLOGY
- 27-Hydroxycholesterol Inhibits Sterol Regulatory Element-Binding Protein 1 Activation and Hepatic Lipid Accumulation in Mice
- (2018) Di Li et al. Obesity
- Single cell analysis of kynurenine and System L amino acid transport in T cells
- (2018) Linda V. Sinclair et al. Nature Communications
- Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
- (2018) Róisín M. Loftus et al. Nature Communications
- The hypoxic tumour microenvironment
- (2018) Varvara Petrova et al. Oncogenesis
- Implication of Interleukin-12/15/18 and Ruxolitinib in the Phenotype, Proliferation, and Polyfunctionality of Human Cytokine-Preactivated Natural Killer Cells
- (2018) Iñigo Terrén et al. Frontiers in Immunology
- Upregulation of 24(R/S),25-epoxycholesterol and 27-hydroxycholesterol suppresses the proliferation and migration of gastric cancer cells
- (2018) Fenghua Guo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Education-dependent activation of glycolysis promotes the cytolytic potency of licensed human natural killer cells
- (2018) Jolie R. Schafer et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- ARID5B regulates metabolic programming in human adaptive NK cells
- (2018) Frank Cichocki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71
- (2018) Wilhelm Salzberger et al. PLoS One
- Prostaglandin E2 Secreted by Thyroid Cancer Cells Contributes to Immune Escape Through the Suppression of Natural Killer (NK) Cell Cytotoxicity and NK Cell Differentiation
- (2018) Arum Park et al. Frontiers in Immunology
- Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
- (2018) Pascale André et al. CELL
- Targeting Adenosine Receptor Signaling in Cancer Immunotherapy
- (2018) Kevin Sek et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
- (2018) Xavier Michelet et al. NATURE IMMUNOLOGY
- Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function
- (2018) Fangjie Wang et al. Nature Communications
- Lactate-mediated acidification of tumor microenvironment induces apoptosis of liver-resident NK cells in colorectal liver metastasis
- (2018) Cathal Harmon et al. Cancer Immunology Research
- Tumor Microenvironment-Induced Immunometabolic Reprogramming of Natural Killer Cells
- (2018) Andrea M. Chambers et al. Frontiers in Immunology
- Adenosinergic Signaling Alters Natural Killer Cell Functional Responses
- (2018) Andrea M. Chambers et al. Frontiers in Immunology
- Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
- (2018) Monica Parodi et al. Frontiers in Immunology
- Natural Killer Cell Education Is Associated With a Distinct Glycolytic Profile
- (2018) Caroline Pfeifer et al. Frontiers in Immunology
- Hypoxia and B cells
- (2017) Natalie Burrows et al. EXPERIMENTAL CELL RESEARCH
- Cutting Edge: IL-2–Induced Expression of the Amino Acid Transporters SLC1A5 and CD98 Is a Prerequisite for NKG2D-Mediated Activation of Human NK Cells
- (2017) Helle Jensen et al. JOURNAL OF IMMUNOLOGY
- Natural killer cell metabolism
- (2017) Takumi Kobayashi et al. MOLECULAR IMMUNOLOGY
- NK cell-based immunotherapy for cancer
- (2017) Fang Fang et al. SEMINARS IN IMMUNOLOGY
- Myeloid-Derived Suppressor Cells
- (2017) Dmitry I. Gabrilovich Cancer Immunology Research
- Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation
- (2017) Markus Granzin et al. Frontiers in Immunology
- NK Cell Exhaustion
- (2017) Jiacheng Bi et al. Frontiers in Immunology
- Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment
- (2017) Kathrin Renner et al. Frontiers in Immunology
- Regulation of mTOR, Metabolic Fitness, and Effector Functions by Cytokines in Natural Killer Cells
- (2017) Sébastien Viel et al. Cancers
- IL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells
- (2016) Y. Mao et al. BLOOD
- Selection and expansion of natural killer cells for NK cell-based immunotherapy
- (2016) Petra S. A. Becker et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
- (2016) Almut Brand et al. Cell Metabolism
- Natural Killer Cells to the Attack: Combination Therapy against Neuroblastoma
- (2016) Olatz Zenarruzabeitia et al. CLINICAL CANCER RESEARCH
- Metabolic Regulation of Natural Killer Cell IFN-γ Production
- (2016) Annelise Y. Mah et al. CRITICAL REVIEWS IN IMMUNOLOGY
- Short Term Hypoxia Synergizes with Interleukin 15 Priming in Driving Glycolytic Gene Transcription and Supports Human Natural Killer Cell Activities
- (2016) Sonia Y. Velásquez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diacylglycerol Kinase ζ Is a Target To Enhance NK Cell Function
- (2016) Enjun Yang et al. JOURNAL OF IMMUNOLOGY
- Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5′-Monophosphate–Activated Protein Kinase
- (2016) Bojana Müller-Durovic et al. JOURNAL OF IMMUNOLOGY
- Metabolic Reprogramming Supports IFN-γ Production by CD56brightNK Cells
- (2016) Sinéad E. Keating et al. JOURNAL OF IMMUNOLOGY
- TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
- (2016) Sébastien Viel et al. Science Signaling
- Nutrient sensing, signal transduction and immune responses
- (2016) Jessica Walls et al. SEMINARS IN IMMUNOLOGY
- Repression of GSK3 restores NK cell cytotoxicity in AML patients
- (2016) Reshmi Parameswaran et al. Nature Communications
- NK cell count and glucotransporter 4 (GLUT4) expression in subjects with type 2 diabetes and colon cancer
- (2016) Paweł Piątkiewicz et al. Diabetology & Metabolic Syndrome
- Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host
- (2016) Anna Schurich et al. Cell Reports
- TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
- (2016) Sébastien Viel et al. Science Signaling
- A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
- (2016) Akio Ohta Frontiers in Immunology
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
- (2015) Chih-Hao Chang et al. CELL
- Metabolic Reprogramming of Immune Cells in Cancer Progression
- (2015) Subhra K. Biswas IMMUNITY
- Activation-Specific Metabolic Requirements for NK Cell IFN-γ Production
- (2015) Molly P. Keppel et al. JOURNAL OF IMMUNOLOGY
- Critical Role of Tumor Microenvironment in Shaping NK Cell Functions: Implication of Hypoxic Stress
- (2015) Meriem Hasmim et al. Frontiers in Immunology
- Effect of tumor cells and tumor microenvironment on NK-cell function
- (2014) Massimo Vitale et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
- (2014) Raymond P. Donnelly et al. JOURNAL OF IMMUNOLOGY
- The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
- (2014) Antoine Marçais et al. NATURE IMMUNOLOGY
- The Critical Role of IL-15–PI3K–mTOR Pathway in Natural Killer Cell Effector Functions
- (2014) Neethi Nandagopal et al. Frontiers in Immunology
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC
- (2013) Mirna Balsamo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
- (2013) Z. Husain et al. JOURNAL OF IMMUNOLOGY
- Hypoxia Induced Impairment of NK Cell Cytotoxicity against Multiple Myeloma Can Be Overcome by IL-2 Activation of the NK Cells
- (2013) Subhashis Sarkar et al. PLoS One
- Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia
- (2013) J. Baginska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- 27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth
- (2013) Qian Wu et al. Cell Reports
- The Critical Role of the Tumor Microenvironment in Shaping Natural Killer Cell-Mediated Anti-Tumor Immunity
- (2013) Joanna Baginska et al. Frontiers in Immunology
- Altered functions of natural killer cells in response to L-Arginine availability
- (2012) Bruno Lamas et al. CELLULAR IMMUNOLOGY
- Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO
- (2011) Tuanjie Li et al. CANCER LETTERS
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity
- (2010) X. Liu et al. BLOOD
- IL-2−driven Regulation of NK Cell Receptors With Regard to the Distribution of CD16+ and CD16− Subpopulations and In Vivo Influence After Haploidentical NK Cell Infusion
- (2010) Sabine Huenecke et al. JOURNAL OF IMMUNOTHERAPY
- Regulation of NK Cell Function by Human Granulocyte Arginase
- (2009) J. Oberlies et al. JOURNAL OF IMMUNOLOGY
- Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
- (2008) Candace M. Cham et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
- (2008) Nancie J. MacIver et al. JOURNAL OF LEUKOCYTE BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started