An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome

Deciphering the chronology of copy number alterations in Multiple Myeloma

(2019) Anil Aktas Samur et al.   Blood Cancer Journal

The future of myeloma precision medicine: integrating the compendium of known drug resistance mechanisms with emerging tumor profiling technologies

(2019) Taylor Harding et al.   LEUKEMIA

High subclonal fraction of 17p deletion is associated with poor prognosis in multiple myeloma

(2019) Anjan Thakurta et al.   BLOOD

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

(2018) Niccolo Bolli et al.   LEUKEMIA

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

(2018) Brian A. Walker et al.   LEUKEMIA

Epigenetic Reprogramming of Pericentromeric Satellite DNA in Premalignant and Malignant Lesions

(2018) Nadine Heidi Brückmann et al.   MOLECULAR CANCER RESEARCH

The multiple myelomas — current concepts in cytogenetic classification and therapy

(2018) Shaji K. Kumar et al.   Nature Reviews Clinical Oncology

Determinants and clinical implications of chromosomal instability in cancer

(2018) Laurent Sansregret et al.   Nature Reviews Clinical Oncology

ARNT /HIF-1β links high-risk 1q21 gain and microenvironmental hypoxia to drug resistance and poor prognosis in multiple myeloma

(2018) Chuan Wu et al.   Cancer Medicine

Subclonal TP53 copy number is associated with prognosis in multiple myeloma

(2018) Vallari Shah et al.   BLOOD

Knick-knack PADIMAC

(2018) Brian A. Walker   BLOOD

Epigenetics in multiple myeloma: From mechanisms to therapy

(2017) Mohammad Alzrigat et al.   SEMINARS IN CANCER BIOLOGY

Rebuilding Chromosomes After Catastrophe: Emerging Mechanisms of Chromothripsis

(2017) Peter Ly et al.   TRENDS IN CELL BIOLOGY

Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma

(2017) Elisa Lazzari et al.   Nature Communications

Chromosomal Instability as a Driver of Tumor Heterogeneity and Evolution

(2017) Samuel F. Bakhoum et al.   Cold Spring Harbor Perspectives in Medicine

Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group

(2016) P. Sonneveld et al.   BLOOD

Regulation of Transient Site-specific Copy Gain by MicroRNA

(2016) Joshua C. Black et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma

(2016) J R Sawyer et al.   LEUKEMIA

Genomic complexity of multiple myeloma and its clinical implications

(2016) Salomon Manier et al.   Nature Reviews Clinical Oncology

Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma

(2015) J. R. Sawyer et al.   BLOOD

Hypoxia drives transient site-specific copy gain and drug-resistant gene expression

(2015) Joshua C. Black et al.   GENES & DEVELOPMENT

Defining and treating high-risk multiple myeloma

(2015) S Z Usmani et al.   LEUKEMIA

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

(2015) Francesca Bersani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease

(2014) J. R. Sawyer et al.   BLOOD

KDM4A Lysine Demethylase Induces Site-Specific Copy Gain and Rereplication of Regions Amplified in Tumors

(2013) Joshua C. Black et al.   CELL

Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

(2013) Teresa Davoli et al.   CELL

Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects

(2013) Corry MR Weemaes et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

IMWG consensus on risk stratification in multiple myeloma

(2013) W J Chng et al.   LEUKEMIA

Long-Term Analysis of the IFM 99 Trials for Myeloma: Cytogenetic Abnormalities [t(4;14), del(17p), 1q gains] Play a Major Role in Defining Long-Term Survival

(2012) Hervé Avet-Loiseau et al.   JOURNAL OF CLINICAL ONCOLOGY

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

(2012) L López-Corral et al.   LEUKEMIA

DNA breaks and chromosome pulverization from errors in mitosis

(2012) Karen Crasta et al.   NATURE

Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients

(2011) F. Magrangeas et al.   BLOOD

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial

(2011) K D Boyd et al.   LEUKEMIA

Ultra High-Risk Myeloma

(2011) H. Avet-Loiseau   Hematology-American Society of Hematology Education Program

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

(2010) B. A. Walker et al.   BLOOD

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12∼23 amplicon

(2009) Jeffrey R. Sawyer et al.   BRITISH JOURNAL OF HAEMATOLOGY

Differential repetitive DNA methylation in multiple myeloma molecular subgroups

(2009) V. Bollati et al.   CARCINOGENESIS

Prognostic Significance of Copy-Number Alterations in Multiple Myeloma

(2009) Hervé Avet-Loiseau et al.   JOURNAL OF CLINICAL ONCOLOGY

Dysfunctional homologous recombination mediates genomic instability and progression in myeloma

(2008) M. A. Shammas et al.   BLOOD

Defining ‘chromosomal instability’

(2008) Jochen B. Geigl et al.   TRENDS IN GENETICS