Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma

ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis

(2016) Maria Anna Zipeto et al.   Cell Stem Cell

RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML

(2016) Leslie A. Crews et al.   Cell Stem Cell

Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche

(2016) Michela Colombo et al.   Oncotarget

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group

(2015) Antonio Palumbo et al.   JOURNAL OF CLINICAL ONCOLOGY

GLI2 inhibition abrogates human leukemia stem cell dormancy

(2015) Anil Sadarangani et al.   Journal of Translational Medicine

An RNA editing fingerprint of cancer stem cell reprogramming

(2015) Leslie A Crews et al.   Journal of Translational Medicine

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

(2015) C Anadón et al.   ONCOGENE

A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance

(2014) Z. Liu et al.   BLOOD

Robust isolation of malignant plasma cells in multiple myeloma

(2014) I. Frigyesi et al.   BLOOD

Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy

(2014) Jens G. Lohr et al.   CANCER CELL

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

(2014) Niccolo Bolli et al.   Nature Communications

RNA-Seq Analysis Identifies a Novel Set of Editing Substrates for Human ADAR2 Present in Saccharomyces cerevisiae

(2013) Tristan Eifler et al.   BIOCHEMISTRY

A Pan-BCL2 Inhibitor Renders Bone-Marrow-Resident Human Leukemia Stem Cells Sensitive to Tyrosine Kinase Inhibition

(2013) Daniel J. Goff et al.   Cell Stem Cell

Effective Alu Repeat Based RT-Qpcr Normalization in Cancer Cell Perturbation Experiments

(2013) Ali Rihani et al.   PLoS One

RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling

(2013) Takashi Shimokawa et al.   RNA Biology

Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma

(2012) S. Blotta et al.   BLOOD

CD19−CD45low/−CD38high/CD138+ plasma cells enrich for human tumorigenic myeloma cells

(2012) D Kim et al.   LEUKEMIA

A distant cis acting intronic element induces site-selective RNA editing

(2012) Chammiran Daniel et al.   NUCLEIC ACIDS RESEARCH

NOTCH1 Signaling Promotes Human T-Cell Acute Lymphoblastic Leukemia Initiating Cell Regeneration in Supportive Niches

(2012) Wenxue Ma et al.   PLoS One

ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia

(2012) Q. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lenalidomide downregulates the cell survival factor, interferon regulatory factor-4, providing a potential mechanistic link for predicting response

(2011) Antonia Lopez-Girona et al.   BRITISH JOURNAL OF HAEMATOLOGY

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma

(2011) R R Singh et al.   ONCOGENE

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions

(2010) Chang Xiao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The RNA Editor Gene ADAR1 is Induced in Myoblasts by Inflammatory Ligands and Buffers Stress Response

(2010) Micah Meltzer et al.   CTS-Clinical and Translational Science

Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates

(2010) N. Paz-Yaacov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gain of 1q21 Is an Unfavorable Genetic Prognostic Factor for Multiple Myeloma Patients Treated with High-Dose Chemotherapy

(2009) Pavel Nemec et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Hedgehog Signaling Is Dispensable for Adult Hematopoietic Stem Cell Function

(2009) Jie Gao et al.   Cell Stem Cell

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

The Vienna RNA Websuite

(2008) A. R. Gruber et al.   NUCLEIC ACIDS RESEARCH