Safety out of control: dopamine and defence

Examining the role of dopamine D2 and D3 receptors in Pavlovian conditioned approach behaviors

(2016) Kurt M. Fraser et al.   BEHAVIOURAL BRAIN RESEARCH

Nucleus Accumbens Core and Shell Differentially Encode Reward-Associated Cues after Reinforcer Devaluation

(2016) E. A. West et al.   JOURNAL OF NEUROSCIENCE

Mechanisms and functions of GABA co-release

(2016) Nicolas X. Tritsch et al.   NATURE REVIEWS NEUROSCIENCE

Dopamine reward prediction-error signalling: a two-component response

(2016) Wolfram Schultz   NATURE REVIEWS NEUROSCIENCE

Depression: A Decision-Theoretic Analysis

(2015) Quentin J.M. Huys et al.   Annual Review of Neuroscience

The Nucleus Accumbens: An Interface Between Cognition, Emotion, and Action

(2015) Stan B. Floresco   Annual Review of Psychology

A role of nucleus accumbens dopamine receptors in the nucleus accumbens core, but not shell, in fear prediction error.

(2015) Susan S. Y. Li et al.   BEHAVIORAL NEUROSCIENCE

Parallel basal ganglia circuits for voluntary and automatic behaviour to reach rewards

(2015) Hyoung F. Kim et al.   BRAIN

Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping

(2015) Kevin T. Beier et al.   CELL

Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits

(2015) Talia N. Lerner et al.   CELL

Reinforcement learning models and their neural correlates: An activation likelihood estimation meta-analysis

(2015) Henry W. Chase et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Activation of Dorsal Raphe Serotonergic Neurons Promotes Waiting but Is Not Reinforcing

(2015) Madalena S. Fonseca et al.   CURRENT BIOLOGY

Differential Dopamine Release Dynamics in the Nucleus Accumbens Core and Shell Reveal Complementary Signals for Error Prediction and Incentive Motivation

(2015) Michael P. Saddoris et al.   JOURNAL OF NEUROSCIENCE

Evidence against dopamine D1/D2 receptor heteromers

(2015) A L Frederick et al.   MOLECULAR PSYCHIATRY

Stress effects on the neural substrates of motivated behavior

(2015) Nick G Hollon et al.   NATURE NEUROSCIENCE

The indirect pathway of the nucleus accumbens shell amplifies neuropathic pain

(2015) Wenjie Ren et al.   NATURE NEUROSCIENCE

Dopaminergic and glutamatergic microdomains in a subset of rodent mesoaccumbens axons

(2015) Shiliang Zhang et al.   NATURE NEUROSCIENCE

Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections

(2015) Yonatan M Kupchik et al.   NATURE NEUROSCIENCE

Mesolimbic dopamine signals the value of work

(2015) Arif A Hamid et al.   NATURE NEUROSCIENCE

Role of Dopamine Neurons in Reward and Aversion: A Synaptic Plasticity Perspective

(2015) Marco Pignatelli et al.   NEURON

Dopamine D2 Modulation of Sign and Goal Tracking in Rats

(2015) Juan Carlos Lopez et al.   NEUROPSYCHOPHARMACOLOGY

Norepinephrine and dopamine transmission in 2 limbic regions differentially respond to acute noxious stimulation

(2015) Jinwoo Park et al.   PAIN

Neuronal Reward and Decision Signals: From Theories to Data

(2015) Wolfram Schultz   PHYSIOLOGICAL REVIEWS

Subsecond dopamine fluctuations in human striatum encode superposed error signals about actual and counterfactual reward

(2015) Kenneth T. Kishida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ventral tegmental area dopamine revisited: effects of acute and repeated stress

(2015) Elizabeth N. Holly et al.   PSYCHOPHARMACOLOGY

Anxiety-Like Behavioural Inhibition Is Normative under Environmental Threat-Reward Correlations

(2015) Dominik R. Bach   PLoS Computational Biology

Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass

(2015) William Menegas et al.   eLife

Reassessing Models of Basal Ganglia Function and Dysfunction

(2014) Alexandra B. Nelson et al.   Annual Review of Neuroscience

Model-based and model-free Pavlovian reward learning: Revaluation, revision, and revelation

(2014) Peter Dayan et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Optogenetic Activation of Dorsal Raphe Serotonin Neurons Enhances Patience for Future Rewards

(2014) Kayoko W. Miyazaki et al.   CURRENT BIOLOGY

Free-Operant Avoidance Behavior by Rats after Reinforcer Revaluation Using Opioid Agonists and D-Amphetamine

(2014) A. Fernando et al.   JOURNAL OF NEUROSCIENCE

Direct and indirect pathways of basal ganglia: a critical reappraisal

(2014) Paolo Calabresi et al.   NATURE NEUROSCIENCE

Dorsal Raphe Neurons Signal Reward through 5-HT and Glutamate

(2014) Zhixiang Liu et al.   NEURON

Neural Computations Underlying Arbitration between Model-Based and Model-free Learning

(2014) Sang Wan Lee et al.   NEURON

The Habenulo-Raphe Serotonergic Circuit Encodes an Aversive Expectation Value Essential for Adaptive Active Avoidance of Danger

(2014) Ryunosuke Amo et al.   NEURON

Executive and modulatory neural circuits of defensive reactions: Implications for panic disorder

(2014) Newton S. Canteras et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The algorithmic anatomy of model-based evaluation

(2014) N. D. Daw et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Dopamine-associated cached values are not sufficient as the basis for action selection

(2014) Nick G. Hollon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opponent actor learning (OpAL): Modeling interactive effects of striatal dopamine on reinforcement learning and choice incentive.

(2014) Anne G. E. Collins et al.   PSYCHOLOGICAL REVIEW

Decreased motivation during chronic pain requires long-term depression in the nucleus accumbens

(2014) N. Schwartz et al.   SCIENCE

Enhancing Depression Mechanisms in Midbrain Dopamine Neurons Achieves Homeostatic Resilience

(2014) A. K. Friedman et al.   SCIENCE

Action versus valence in decision making

(2014) Marc Guitart-Masip et al.   TRENDS IN COGNITIVE SCIENCES

Striatal dopamine D1 receptor is essential for contextual fear conditioning

(2014) Masaru Ikegami et al.   Scientific Reports

Local control of striatal dopamine release

(2014) Roger Cachope et al.   Frontiers in Behavioral Neuroscience

Dopamine D2 receptors modulate the expression of contextual conditioned fear

(2013) Kátia A. de Souza Caetano et al.   BEHAVIOURAL PHARMACOLOGY

Enhanced Avoidance Habits in Obsessive-Compulsive Disorder

(2013) Claire M. Gillan et al.   BIOLOGICAL PSYCHIATRY

Computational heterogeneity in the human mesencephalic dopamine system

(2013) Kimberlee D’Ardenne et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Cocaine-induced adaptations in D1 and D2 accumbens projection neurons (a dichotomy not necessarily synonymous with direct and indirect pathways)

(2013) Rachel J Smith et al.   CURRENT OPINION IN NEUROBIOLOGY

Safety Signals in the Primate Amygdala

(2013) R. Genud-Gabai et al.   JOURNAL OF NEUROSCIENCE

Safety Encoding in the Basal Amygdala

(2013) S. Sangha et al.   JOURNAL OF NEUROSCIENCE

Concurrent activation of striatal direct and indirect pathways during action initiation

(2013) Guohong Cui et al.   NATURE

Dopamine and extinction: A convergence of theory with fear and reward circuitry

(2013) Antony D. Abraham et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Goals and Habits in the Brain

(2013) Ray J. Dolan et al.   NEURON

Reward and aversion in a heterogeneous midbrain dopamine system

(2013) Stephan Lammel et al.   NEUROPHARMACOLOGY

Neurocircuitry of drug reward

(2013) Satoshi Ikemoto et al.   NEUROPHARMACOLOGY

Learning not to Fear: Neural Correlates of Learned Safety

(2013) Eryan Kong et al.   NEUROPSYCHOPHARMACOLOGY

The Role of the Nucleus Accumbens Shell in the Mediation of the Reinforcing Properties of a Safety Signal in Free-Operant Avoidance: Dopamine-Dependent Inhibitory Effects of d-amphetamine

(2013) Anushka BP Fernando et al.   NEUROPSYCHOPHARMACOLOGY

Dopamine Modulates Reward-Related Vigor

(2013) Ulrik Beierholm et al.   NEUROPSYCHOPHARMACOLOGY

Neural and Behavioral Evidence for an Intrinsic Cost of Self-Control

(2013) Wouter Kool et al.   PLoS One

 FosB differentially modulates nucleus accumbens direct and indirect pathway function

(2013) B. A. Grueter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Dimensions of Value: Dopamine Neurons Represent Reward But Not Aversiveness

(2013) C. D. Fiorillo   SCIENCE

Aversive stimuli and loss in the mesocorticolimbic dopamine system

(2013) Andrew M. Brooks et al.   TRENDS IN COGNITIVE SCIENCES

Neural Basis of Reinforcement Learning and Decision Making

(2012) Daeyeol Lee et al.   Annual Review of Neuroscience

How to set the switches on this thing

(2012) Peter Dayan   CURRENT OPINION IN NEUROBIOLOGY

The ubiquity of model-based reinforcement learning

(2012) Bradley B Doll et al.   CURRENT OPINION IN NEUROBIOLOGY

Updating dopamine reward signals

(2012) Wolfram Schultz   CURRENT OPINION IN NEUROBIOLOGY

The role of dopamine in the accumbens core in the expression of Pavlovian-conditioned responses

(2012) Benjamin T. Saunders et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Instrumental vigour in punishment and reward

(2012) Peter Dayan   EUROPEAN JOURNAL OF NEUROSCIENCE

Inhibition of Fear by Learned Safety Signals: A Mini-Symposium Review

(2012) J. P. Christianson et al.   JOURNAL OF NEUROSCIENCE

Subsecond Dopamine Release in the Nucleus Accumbens Predicts Conditioned Punishment and Its Successful Avoidance

(2012) E. B. Oleson et al.   JOURNAL OF NEUROSCIENCE

Aversive Stimuli Differentially Modulate Real-Time Dopamine Transmission Dynamics within the Nucleus Accumbens Core and Shell

(2012) A. Badrinarayan et al.   JOURNAL OF NEUROSCIENCE

Neuron-type-specific signals for reward and punishment in the ventral tegmental area

(2012) Jeremiah Y. Cohen et al.   NATURE

Dopaminergic neurons inhibit striatal output through non-canonical release of GABA

(2012) Nicolas X. Tritsch et al.   NATURE

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

(2012) Dipesh Chaudhury et al.   NATURE

Distinct roles for direct and indirect pathway striatal neurons in reinforcement

(2012) Alexxai V Kravitz et al.   NATURE NEUROSCIENCE

The many paths to fear

(2012) Cornelius T. Gross et al.   NATURE REVIEWS NEUROSCIENCE

Dopaminergic Modulation of Synaptic Transmission in Cortex and Striatum

(2012) Nicolas X. Tritsch et al.   NEURON

Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons

(2012) Sarah Threlfell et al.   NEURON

The Mysterious Motivational Functions of Mesolimbic Dopamine

(2012) John D. Salamone et al.   NEURON

The novel adenosine A2A antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions

(2012) Jessica L. Santerre et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Pathway-specific modulation of nucleus accumbens in reward and aversive behavior via selective transmitter receptors

(2012) T. Hikida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contributions of the ventromedial prefrontal cortex to goal-directed action selection

(2011) John P. O’Doherty   Annals of the New York Academy of Sciences

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Dopaminergic axons in different divisions of the adult rat striatal complex do not express vesicular glutamate transporters

(2011) Jonathan Moss et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Vigor in the Face of Fluctuating Rates of Reward: An Experimental Examination

(2011) Marc Guitart-Masip et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Nucleus accumbens shell, but not core, tracks motivational value of salt

(2011) Amy L. Loriaux et al.   JOURNAL OF NEUROPHYSIOLOGY

Nucleus Accumbens Dopamine/Glutamate Interaction Switches Modes to Generate Desire versus Dread: D1 Alone for Appetitive Eating But D1 and D2 Together for Fear

(2011) J. M. Richard et al.   JOURNAL OF NEUROSCIENCE

Signals in Human Striatum Are Appropriate for Policy Update Rather than Value Prediction

(2011) J. Li et al.   JOURNAL OF NEUROSCIENCE

The General and Outcome-Specific Forms of Pavlovian-Instrumental Transfer Are Differentially Mediated by the Nucleus Accumbens Core and Shell

(2011) L. H. Corbit et al.   JOURNAL OF NEUROSCIENCE

Requirement of dopamine signaling in the amygdala and striatum for learning and maintenance of a conditioned avoidance response

(2011) M. Darvas et al.   LEARNING & MEMORY

Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety

(2011) Larry S Zweifel et al.   NATURE NEUROSCIENCE

From reinforcement learning models to psychiatric and neurological disorders

(2011) Tiago V Maia et al.   NATURE NEUROSCIENCE

Projection-Specific Modulation of Dopamine Neuron Synapses by Aversive and Rewarding Stimuli

(2011) Stephan Lammel et al.   NEURON

Model-Based Influences on Humans' Choices and Striatal Prediction Errors

(2011) Nathaniel D. Daw et al.   NEURON

Dopamine release in the basal ganglia

(2011) M.E. Rice et al.   NEUROSCIENCE

Aversive stimulus differentially triggers subsecond dopamine release in reward regions

(2011) E.A. Budygin et al.   NEUROSCIENCE

The mesoaccumbens dopamine in coping with stress

(2011) Simona Cabib et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

A translational bridge between mouse and human models of learned safety

(2010) Daniela D. Pollak et al.   ANNALS OF MEDICINE

Synaptic plasticity in the mesolimbic system

(2010) Billy T. Chen et al.   Annals of the New York Academy of Sciences

At the limbic-motor interface: disconnection of basolateral amygdala from nucleus accumbens core and shell reveals dissociable components of incentive motivation

(2010) Michael W. Shiflett et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Pallidus-Habenula-Dopamine Pathway Signals Inferred Stimulus Values

(2010) Ethan S. Bromberg-Martin et al.   JOURNAL OF NEUROPHYSIOLOGY

Influence of Phasic and Tonic Dopamine Release on Receptor Activation

(2010) J. K. Dreyer et al.   JOURNAL OF NEUROSCIENCE

Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate

(2010) G. D. Stuber et al.   JOURNAL OF NEUROSCIENCE

Glutamatergic Signaling by Mesolimbic Dopamine Neurons in the Nucleus Accumbens

(2010) F. Tecuapetla et al.   JOURNAL OF NEUROSCIENCE

The Flexible Approach Hypothesis: Unification of Effort and Cue-Responding Hypotheses for the Role of Nucleus Accumbens Dopamine in the Activation of Reward-Seeking Behavior

(2010) S. M. Nicola   JOURNAL OF NEUROSCIENCE

Two-factor theory, the actor--critic model, and conditioned avoidance

(2010) T. V. Maia   LEARNING & BEHAVIOR

The role of amygdala nuclei in the expression of auditory signaled two-way active avoidance in rats

(2010) J.-S. Choi et al.   LEARNING & MEMORY

A selective role for dopamine in stimulus–reward learning

(2010) Shelly B. Flagel et al.   NATURE

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

Neurogenetics and Pharmacology of Learning, Motivation and Cognition

(2010) Michael J Frank et al.   NEUROPSYCHOPHARMACOLOGY

Opponency Revisited: Competition and Cooperation Between Dopamine and Serotonin

(2010) Y-Lan Boureau et al.   NEUROPSYCHOPHARMACOLOGY

Nucleus accumbens and effort-related functions: behavioral and neural markers of the interactions between adenosine A2A and dopamine D2 receptors

(2010) A.M. Farrar et al.   NEUROSCIENCE

Prefrontal cortex, cognitive control, and the registration of decision costs

(2010) Joseph T. McGuire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absence of NMDA receptors in dopamine neurons attenuates dopamine release but not conditioned approach during Pavlovian conditioning

(2010) J. G. Parker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serotonin in Affective Control

(2009) Peter Dayan et al.   Annual Review of Neuroscience

A specific role for posterior dorsolateral striatum in human habit learning

(2009) Elizabeth Tricomi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Synaptic Overflow of Dopamine in the Nucleus Accumbens Arises from Neuronal Activity in the Ventral Tegmental Area

(2009) L. A. Sombers et al.   JOURNAL OF NEUROSCIENCE

Dopamine Is Necessary for Cue-Dependent Fear Conditioning

(2009) J. P. Fadok et al.   JOURNAL OF NEUROSCIENCE

Two types of dopamine neuron distinctly convey positive and negative motivational signals

(2009) Masayuki Matsumoto et al.   NATURE

Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine

(2009) Jerylin O Gan et al.   NATURE NEUROSCIENCE

Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action

(2009) Bernard W Balleine et al.   NEUROPSYCHOPHARMACOLOGY

Calcium signaling cascade links dopamine D1–D2 receptor heteromer to striatal BDNF production and neuronal growth

(2009) Ahmed Hasbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli

(2009) F. Brischoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of dopamine receptor mechanisms in the amygdaloid modulation of fear and anxiety: Structural and functional analysis

(2009) Miguel Pérez de la Mora et al.   PROGRESS IN NEUROBIOLOGY

The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward.

(2009) Mark D. Humphries et al.   PROGRESS IN NEUROBIOLOGY

Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice

(2009) Emmanuel Valjent et al.   TRENDS IN NEUROSCIENCES

Do Substantia Nigra Dopaminergic Neurons Differentiate Between Reward and Punishment?

(2009) M. J. Frank et al.   Journal of Molecular Cell Biology

Role of dopamine D1 and D2 receptors in the nucleus accumbens shell on the acquisition and expression of fructose-conditioned flavor–flavor preferences in rats

(2008) Sonia Y. Bernal et al.   BEHAVIOURAL BRAIN RESEARCH

Neurocomputational models of basal ganglia function in learning, memory and choice

(2008) Michael X. Cohen et al.   BEHAVIOURAL BRAIN RESEARCH

Determining a Role for Ventromedial Prefrontal Cortex in Encoding Action-Based Value Signals During Reward-Related Decision Making

(2008) Jan Gläscher et al.   CEREBRAL CORTEX

Role of central dopamine in pain and analgesia

(2008) Patrick B Wood   Expert Review of Neurotherapeutics

Mesolimbic Dopamine in Desire and Dread: Enabling Motivation to Be Generated by Localized Glutamate Disruptions in Nucleus Accumbens

(2008) A. Faure et al.   JOURNAL OF NEUROSCIENCE

Opposing Patterns of Signaling Activation in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol

(2008) J. Bertran-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Dopamine D1 and D2 receptors in the nucleus accumbens core and shell mediate Pavlovian-instrumental transfer

(2008) A. Lex et al.   LEARNING & MEMORY

Emotional environments retune the valence of appetitive versus fearful functions in nucleus accumbens

(2008) Sheila M Reynolds et al.   NATURE NEUROSCIENCE

A common neurobiology for pain and pleasure

(2008) Siri Leknes et al.   NATURE REVIEWS NEUROSCIENCE

A temporal difference account of avoidance learning

(2008) Michael Moutoussis et al.   NETWORK-COMPUTATION IN NEURAL SYSTEMS

Unique Properties of Mesoprefrontal Neurons within a Dual Mesocorticolimbic Dopamine System

(2008) Stephan Lammel et al.   NEURON

Biological substrates of reward and aversion: A nucleus accumbens activity hypothesis

(2008) William A. Carlezon et al.   NEUROPHARMACOLOGY

Role of Dopamine in the Motivational and Cognitive Control of Behavior

(2008) Roshan Cools   NEUROSCIENTIST

Dichotomous Dopaminergic Control of Striatal Synaptic Plasticity

(2008) W. Shen et al.   SCIENCE

Dopaminergic Innervation of the Amygdala Is Highly Responsive to Stress

(2003) Fiona M. Inglis et al.   JOURNAL OF NEUROCHEMISTRY