Lysosomal Destabilizing Drug Siramesine and the Dual Tyrosine Kinase Inhibitor Lapatinib Induce a Synergistic Ferroptosis through Reduced Heme Oxygenase-1 (HO-1) Levels

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

Heme oxygenase-1 mediates BAY 11–7085 induced ferroptosis

(2018) Ling-Chu Chang et al.   CANCER LETTERS

The Nrf2-ARE signaling pathway: An update on its regulation and possible role in cancer prevention and treatment

(2017) Violetta Krajka-Kuźniak et al.   Pharmacological Reports

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance

(2016) A. L. Furfaro et al.   Oxidative Medicine and Cellular Longevity

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

(2016) S Ma et al.   Cell Death & Disease

Bilirubin is an Endogenous Antioxidant in Human Vascular Endothelial Cells

(2016) Lovro Ziberna et al.   Scientific Reports

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

(2015) Xiaofang Sun et al.   HEPATOLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

(2015) Min-Young Kwon et al.   Oncotarget

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3

(2014) Meghan B. Azad et al.   Autophagy

Lysosomotropic agents: impact on lysosomal membrane permeabilization and cell death

(2014) Ana M. Villamil Giraldo et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma

(2013) Sung Su Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules

(2012) Pallavi Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Antioxidant Properties of Bilirubin and Biliverdin. Is there a Role for Biliverdin Reductase?

(2012) Thomas Jansen et al.   Frontiers in Pharmacology

Bilirubin and glutathione have complementary antioxidant and cytoprotective roles

(2009) T. W. Sedlak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysosomes in iron metabolism, ageing and apoptosis

(2008) Tino Kurz et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE