Cutaneous lupus erythematosus: new insights into pathogenesis and therapeutic strategies
出版年份 2019 全文链接
标题
Cutaneous lupus erythematosus: new insights into pathogenesis and therapeutic strategies
作者
关键词
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出版物
Nature Reviews Rheumatology
Volume 15, Issue 9, Pages 519-532
出版商
Springer Science and Business Media LLC
发表日期
2019-08-09
DOI
10.1038/s41584-019-0272-0
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Bortezomib in antibody-mediated autoimmune diseases (TAVAB): study protocol for a unicentric, non-randomised, non-placebo controlled trial
- (2019) Siegfried Kohler et al. BMJ Open
- Delineating the healthy human skin UV response and early induction of interferon pathway in cutaneous lupus erythematosus
- (2019) Shintaro Katayama et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Innate Immune Cells' Contribution to Systemic Lupus Erythematosus
- (2019) Andrés A. Herrada et al. Frontiers in Immunology
- Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus
- (2018) Siriorn Udompanich et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa
- (2018) Mrinal K Sarkar et al. ANNALS OF THE RHEUMATIC DISEASES
- Drug-induced lupus: Traditional and new concepts
- (2018) Augusto Vaglio et al. AUTOIMMUNITY REVIEWS
- The 2018 pipeline of targeted therapies under clinical development for Systemic Lupus Erythematosus: a systematic review of trials
- (2018) Renaud Felten et al. AUTOIMMUNITY REVIEWS
- Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors
- (2018) Tobias Alexander et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus–like inflammation
- (2018) Purvi Mande et al. JOURNAL OF CLINICAL INVESTIGATION
- Type I Immune Response Induces Keratinocyte Necroptosis and Is Associated with Interface Dermatitis
- (2018) Felix Lauffer et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Cigarette smoke modifies neutrophil chemotaxis, neutrophil extracellular trap formation and inflammatory response-related gene expression
- (2018) P. C. White et al. JOURNAL OF PERIODONTAL RESEARCH
- Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 2 trial
- (2018) Daniel J Wallace et al. LANCET
- Type I interferon in rheumatic diseases
- (2018) Theresa L. Wampler Muskardin et al. Nature Reviews Rheumatology
- STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice
- (2018) Morten K. Skouboe et al. PLoS Pathogens
- Nomenclature of Cutaneous Vasculitis
- (2018) Cord H. Sunderkötter et al. Arthritis & Rheumatology
- Efficacy and Safety of Atacicept in Patients With Systemic Lupus Erythematosus
- (2018) Joan T. Merrill et al. Arthritis & Rheumatology
- Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus
- (2018) Takayuki Katsuyama et al. Frontiers in Immunology
- T Follicular Helper Cells in Autoimmune Disorders
- (2018) Noémie Gensous et al. Frontiers in Immunology
- The Absent in Melanoma 2-Like Receptor IFN-Inducible Protein 16 as an Inflammasome Regulator in Systemic Lupus Erythematosus: The Dark Side of Sensing Microbes
- (2018) Valeria Caneparo et al. Frontiers in Immunology
- An evaluation of voclosporin for the treatment of lupus nephritis
- (2018) Fang En Sin et al. EXPERT OPINION ON PHARMACOTHERAPY
- Increased myeloid dendritic cells and TNF-α expression predicts poor response to hydroxychloroquine in cutaneous lupus erythematosus
- (2018) Majid Zeidi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study
- (2018) Ronald F van Vollenhoven et al. LANCET
- Rituximab in systemic autoimmune rheumatic diseases: indications and practical use
- (2018) Nathalie Berghen et al. ACTA CLINICA BELGICA
- Metabolic Pathway of Cyclosporine A and Its Correlation with Nephrotoxicity
- (2018) Qinghua Wu et al. CURRENT DRUG METABOLISM
- PD-1 immunobiology in systemic lupus erythematosus
- (2018) Colleen S. Curran et al. JOURNAL OF AUTOIMMUNITY
- A pre-clinical quantitative model predicts the pharmacokinetics/pharmacodynamics of an anti-BDCA2 monoclonal antibody in humans
- (2018) Konstantinos Biliouris et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- High expression of B lymphocyte stimulator in lesional keratinocytes of patients with cutaneous lupus erythematosus
- (2017) Joerg Wenzel et al. EXPERIMENTAL DERMATOLOGY
- JAK inhibitor ruxolitinib inhibits the expression of cytokines characteristic of cutaneous lupus erythematosus
- (2017) Anna Sophie Klaeschen et al. EXPERIMENTAL DERMATOLOGY
- Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop
- (2017) Jasmine N. Stannard et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Immunostimulatory Endogenous Nucleic Acids Drive the Lesional Inflammation in Cutaneous Lupus Erythematosus
- (2017) Benedikt Scholtissek et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Genomic Investigation of Lupus in the Skin
- (2017) Animesh A. Sinha et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS
- Quinacrine Suppresses Tumor Necrosis Factor-α and IFN-α in Dermatomyositis and Cutaneous Lupus Erythematosus
- (2017) Paul Alves et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS
- Genetic similarities and differences between discoid and systemic lupus erythematosus patients within the Polish population
- (2017) Katarzyna Skonieczna et al. Postepy Dermatologii i Alergologii
- Effects of Hydroxychloroquine in Patients With Cutaneous Lupus Erythematosus: A Multicenter, Double-Blind, Randomized, Parallel-Group Trial
- (2017) N. Yokogawa et al. Arthritis & Rheumatology
- Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus
- (2017) Victoria P. Werth et al. Arthritis & Rheumatology
- Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus
- (2017) Richard Furie et al. Arthritis & Rheumatology
- TWEAK/Fn14 Activation Participates in Ro52-Mediated Photosensitization in Cutaneous Lupus Erythematosus
- (2017) Yale Liu et al. Frontiers in Immunology
- Cutaneous Lupus Erythematosus: An Update on Pathogenesis, Diagnosis and Treatment
- (2016) Emily Z. Hejazi et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- Familial chilblain lupus due to a gain-of-function mutation in STING
- (2016) Nadja König et al. ANNALS OF THE RHEUMATIC DISEASES
- The features of skin inflammation induced by lupus serum
- (2016) Lena Liu et al. CLINICAL IMMUNOLOGY
- Genetic association study of systemic lupus erythematosus and disease subphenotypes in European populations
- (2016) Otsanda Ruiz-Larrañaga et al. CLINICAL RHEUMATOLOGY
- Immunogenetics of cutaneous lupus erythematosus
- (2016) Aimee O. Hersh et al. CURRENT OPINION IN PEDIATRICS
- Cutaneous lupus erythematosus
- (2016) Jasmine N. Stannard et al. CURRENT OPINION IN RHEUMATOLOGY
- Ixazomib: First Global Approval
- (2016) Matt Shirley DRUGS
- The role of Syk in cutaneous lupus erythematosus
- (2016) Guo-Min Deng et al. EXPERIMENTAL DERMATOLOGY
- Spleen tyrosine kinase (SYK) is a potential target for the treatment of cutaneous lupus erythematosus patients
- (2016) Christine Braegelmann et al. EXPERIMENTAL DERMATOLOGY
- Update on the role of plasmacytoid dendritic cells in inflammatory/autoimmune skin diseases
- (2016) Dana Saadeh et al. EXPERIMENTAL DERMATOLOGY
- Therapeutic options for cutaneous lupus erythematosus: recent advances and future prospects
- (2016) Joshua Chang et al. Expert Review of Clinical Immunology
- Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
- (2016) Shailesh Dudhgaonkar et al. JOURNAL OF IMMUNOLOGY
- JAK1/2 Inhibitor Ruxolitinib Controls a Case of Chilblain Lupus Erythematosus
- (2016) Joerg Wenzel et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- S2k guideline for treatment of cutaneous lupus erythematosus - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV)
- (2016) A. Kuhn et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Belimumab for the treatment of recalcitrant cutaneous lupus
- (2016) P Vashisht et al. LUPUS
- Efficacy of abatacept in systemic lupus erythematosus: a retrospective analysis of 11 patients with refractory disease
- (2016) F Danion et al. LUPUS
- Advances in the treatment of cutaneous lupus erythematosus
- (2016) A Kuhn et al. LUPUS
- Fumaric acid ester treatment in cutaneous lupus erythematosus (CLE): a prospective, open-label, phase II pilot study
- (2016) A Kuhn et al. LUPUS
- Biological therapies in the treatment of cutaneous lupus erythematosus
- (2016) J K Presto et al. LUPUS
- Effects of Belimumab on Flare Rate and Expected Damage Progression in Patients With Active Systemic Lupus Erythematosus
- (2016) Luca Iaccarino et al. ARTHRITIS CARE & RESEARCH
- Upcoming therapeutic targets in cutaneous lupus erythematous
- (2016) Anna Sophie Klaeschen et al. Expert Review of Clinical Pharmacology
- Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus
- (2015) Caroline von Spee-Mayer et al. ANNALS OF THE RHEUMATIC DISEASES
- A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)
- (2015) Kenneth C Kalunian et al. ANNALS OF THE RHEUMATIC DISEASES
- Dapsone as Second-Line Treatment for Cutaneous Lupus Erythematosus? A Retrospective Analysis of 34 Patients and a Review of the Literature
- (2015) Martin Klebes et al. DERMATOLOGY
- Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus
- (2015) Manfred Kunz et al. EXPERIMENTAL DERMATOLOGY
- More on Remission of Recalcitrant Dermatomyositis Treated with Ruxolitinib
- (2015) NEW ENGLAND JOURNAL OF MEDICINE
- Mast cells in systemic and cutaneous lupus erythematosus
- (2015) Karolina Kaczmarczyk-Sekuła et al. POLISH JOURNAL OF PATHOLOGY
- Lupus erythematosus revisited
- (2015) Annegret Kuhn et al. Seminars in Immunopathology
- Epidemiology of Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus in a Predominantly White Population in the United States
- (2015) Sudumpai Jarukitsopa et al. ARTHRITIS CARE & RESEARCH
- Brief Report: Responses to Rituximab Suggest B Cell-Independent Inflammation in Cutaneous Systemic Lupus Erythematosus
- (2015) Edward M. Vital et al. Arthritis & Rheumatology
- FcγRIIa and FcγRIIIb polymorphisms and associations with clinical manifestations in systemic lupus erythematosus patients
- (2014) Isabel Cristina Costa Vigato-Ferreira et al. AUTOIMMUNITY
- Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease
- (2014) S. Spoerl et al. BLOOD
- Ultraviolet light protection by a sunscreen prevents interferon-driven skin inflammation in cutaneous lupus erythematosus
- (2014) Sabine Zahn et al. EXPERIMENTAL DERMATOLOGY
- Efficacy of ruxolitinib for myelofibrosis
- (2014) Fabio PS Santos et al. EXPERT OPINION ON PHARMACOTHERAPY
- The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets
- (2014) Mona HC Biermann et al. Expert Review of Clinical Immunology
- Differential gene expression analysis in CCLE lesions provides new insights regarding the genetics basis of skin vs. systemic disease
- (2014) R. Dey-Rao et al. GENOMICS
- The classification and diagnosis of cutaneous lupus erythematosus
- (2014) Annegret Kuhn et al. JOURNAL OF AUTOIMMUNITY
- Double-Stranded RNA Induces an Antiviral Defense Status in Epidermal Keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-Mediated Differential Signaling
- (2014) B. N. Kalali et al. JOURNAL OF IMMUNOLOGY
- Remission of Recalcitrant Dermatomyositis Treated with Ruxolitinib
- (2014) Thorsten Hornung et al. NEW ENGLAND JOURNAL OF MEDICINE
- Systemic Symptoms in the Progression of Cutaneous to Systemic Lupus Erythematosus
- (2014) Isabela T. Wieczorek et al. JAMA Dermatology
- An ENU Mutagenesis-Derived Mouse Model with a Dominant Jak1 Mutation Resembling Phenotypes of Systemic Autoimmune Disease
- (2013) Sibylle Sabrautzki et al. AMERICAN JOURNAL OF PATHOLOGY
- Ultraviolet B irradiation induces skin accumulation of plasmacytoid dendritic cells: A possible role for chemerin
- (2013) Qili Yin et al. AUTOIMMUNITY
- Proton pump inhibitor-induced subacute cutaneous lupus erythematosus
- (2013) L.H. Sandholdt et al. BRITISH JOURNAL OF DERMATOLOGY
- Polymorphisms in STK17A gene are associated with systemic lupus erythematosus and its clinical manifestations
- (2013) Andréia Maria da Silva Fonseca et al. GENE
- Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing
- (2013) Nadine Gehrke et al. IMMUNITY
- Deregulated Type I IFN Response in TREX1-Associated Familial Chilblain Lupus
- (2013) Katrin Peschke et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Characterization of clinical photosensitivity in cutaneous lupus erythematosus
- (2013) Kristen Foering et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus – report of 17 cases and review of the literature
- (2013) SC Hofmann et al. LUPUS
- Vitamin D receptor (VDR) gene polymorphisms and susceptibility to systemic lupus erythematosus clinical manifestations
- (2013) J de Azevêdo Silva et al. LUPUS
- Kutaner Lupus erythematodes und Hautveränderungen beim systemischen Lupus erythematodes
- (2013) M. Sticherling ZEITSCHRIFT FUR RHEUMATOLOGIE
- Cutaneous lupus erythematosus: First multicenter database analysis of 1002 patients from the European Society of Cutaneous Lupus Erythematosus (EUSCLE)
- (2012) Cyrus Biazar et al. AUTOIMMUNITY REVIEWS
- Cytosolic sensing of extracellular self-DNA transported into monocytes by the antimicrobial peptide LL37
- (2012) G. Chamilos et al. BLOOD
- Suppression of UV-induced damage by a liposomal sunscreen: a prospective, open-label study in patients with cutaneous lupus erythematosus and healthy controls
- (2012) Nikolaos Patsinakidis et al. EXPERIMENTAL DERMATOLOGY
- Taming lupus—a new understanding of pathogenesis is leading to clinical advances
- (2012) Zheng Liu et al. NATURE MEDICINE
- Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population
- (2012) Hua Zhong et al. ARTHRITIS RESEARCH & THERAPY
- Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus
- (2011) E. Sanchez et al. ANNALS OF THE RHEUMATIC DISEASES
- The genetics of systemic lupus erythematosus and implications for targeted therapy
- (2011) A. L. Sestak et al. ANNALS OF THE RHEUMATIC DISEASES
- Safety profile and clinical activity of sifalimumab, a fully human anti-interferon monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study
- (2011) J. T. Merrill et al. ANNALS OF THE RHEUMATIC DISEASES
- Successful Treatment of Subacute Lupus Erythematosus With Ustekinumab
- (2011) Aieska De Souza ARCHIVES OF DERMATOLOGY
- Impact of Smoking in Cutaneous Lupus Erythematosus
- (2011) Evan W. Piette ARCHIVES OF DERMATOLOGY
- Interferon-α stimulates TRAIL expression in human keratinocytes and peripheral blood mononuclear cells: implications for the pathogenesis of cutaneous lupus erythematosus
- (2011) S. Zahn et al. BRITISH JOURNAL OF DERMATOLOGY
- Cutaneous lupus erythematosus and the association with systemic lupus erythematosus: a population-based cohort of 1088 patients in Sweden
- (2011) C.M. Grönhagen et al. BRITISH JOURNAL OF DERMATOLOGY
- The selective p38 mitogen-activated protein kinase inhibitor, SB203580, improves renal disease in MRL/lpr mouse model of systemic lupus
- (2011) Na Jin et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines
- (2011) A. Kuznik et al. JOURNAL OF IMMUNOLOGY
- Efficacy of tacrolimus 0.1% ointment in cutaneous lupus erythematosus: A multicenter, randomized, double-blind, vehicle-controlled trial
- (2011) Annegret Kuhn et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Expression of antimicrobial peptides in different subtypes of cutaneous lupus erythematosus
- (2011) Alexander Kreuter et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- The type I interferon system in the etiopathogenesis of autoimmune diseases
- (2011) Lars Rönnblom UPSALA JOURNAL OF MEDICAL SCIENCES
- Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus
- (2010) Sabine Zahn et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Photoprotective effects of a broad-spectrum sunscreen in ultraviolet-induced cutaneous lupus erythematosus: A randomized, vehicle-controlled, double-blind study
- (2010) Annegret Kuhn et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Lupus tumidus induced by bortezomib not requiring discontinuation of the drug
- (2010) I Aguayo-Leiva et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- The need to revisit the nosology of cutaneous lupus erythematosus
- (2010) D. Lipsker LUPUS
- Cutaneous manifestations of complement deficiencies
- (2010) D. Lipsker et al. LUPUS
- Overview of common, rare and atypical manifestations of cutaneous lupus erythematosus and histopathological correlates
- (2010) G. Obermoser et al. LUPUS
- Methotrexate—how does it really work?
- (2010) Edwin S. L. Chan et al. Nature Reviews Rheumatology
- Polymorphisms of the ITGAM Gene Confer Higher Risk of Discoid Cutaneous Than of Systemic Lupus Erythematosus
- (2010) Tiina M. Järvinen et al. PLoS One
- Incidence of Cutaneous Lupus Erythematosus, 1965-2005
- (2009) Olayemi Durosaro et al. ARCHIVES OF DERMATOLOGY
- Regulation of the interferon-α production induced by RNA-containing immune complexes in plasmacytoid dendritic cells
- (2009) Maija-Leena Eloranta et al. ARTHRITIS AND RHEUMATISM
- Identification of granzyme B-expressing CD-8-positive T cells in lymphocytic inflammatory infiltrate in cutaneous lupus erythematosus and in dermatomyositis
- (2009) M. Grassi et al. CLINICAL AND EXPERIMENTAL DERMATOLOGY
- Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus
- (2009) Tiina M. Järvinen et al. EXPERIMENTAL DERMATOLOGY
- Type I interferon-associated cytotoxic inflammation in cutaneous lupus erythematosus
- (2008) Joerg Wenzel et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus
- (2008) Dong Wang et al. ARTHRITIS AND RHEUMATISM
- Efficacy and safety of TNF-blocker therapy in systemic lupus erythematosus
- (2008) Martin Aringer et al. Expert Opinion On Drug Safety
- An IFN-Associated Cytotoxic Cellular Immune Response against Viral, Self-, or Tumor Antigens Is a Common Pathogenetic Feature in “Interface Dermatitis”
- (2008) Joerg Wenzel et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Narrow-band UVB-induced Externalization of Selected Nuclear Antigens in Keratinocytes: Implications for Lupus Erythematosus Pathogenesis
- (2008) Adam Reich et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
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