The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state
出版年份 2019 全文链接
标题
The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state
作者
关键词
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出版物
Nature Reviews Endocrinology
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-25
DOI
10.1038/s41574-019-0256-9
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- HEPATIC TRANSCRIPTOME SIGNATURES IN PATIENTS WITH VARYING DEGREES OF NON-ALCOHOLIC FATTY LIVER DISEASE COMPARED TO HEALTHY NORMAL-WEIGHT INDIVIDUALS
- (2019) Malte P Suppli et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway
- (2019) Yun Li et al. JOURNAL OF LIPID RESEARCH
- Neutral Lipid Storage Diseases as Cellular Model to Study Lipid Droplet Function
- (2019) Sara Missaglia et al. Cells
- The influence of dietary fatty acids on liver fat content and metabolism
- (2019) Leanne Hodson et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- Pharmacological intervention of liver triacylglycerol lipolysis: The good, the bad and the ugly
- (2018) Ariel D. Quiroga et al. BIOCHEMICAL PHARMACOLOGY
- DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates
- (2018) David G. McLaren et al. Cell Metabolism
- Non-alcoholic fatty liver disease and its treatment with n-3 polyunsaturated fatty acids
- (2018) Gabriela S. de Castro et al. CLINICAL NUTRITION
- Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
- (2018) Panu K. Luukkonen et al. DIABETES CARE
- Association of sugar sweetened beverages consumption with non-alcoholic fatty liver disease: a systematic review and meta-analysis
- (2018) Farzaneh Asgari-Taee et al. EUROPEAN JOURNAL OF NUTRITION
- Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes
- (2018) Brittany A. Law et al. FASEB JOURNAL
- NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects
- (2018) Eeva Sliz et al. HUMAN MOLECULAR GENETICS
- Fructose and sugar: A major mediator of non-alcoholic fatty liver disease
- (2018) Thomas Jensen et al. JOURNAL OF HEPATOLOGY
- Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice
- (2018) Albert G. Linden et al. JOURNAL OF LIPID RESEARCH
- Systematic review and meta-analysis of controlled intervention studies on the effectiveness of long-chain omega-3 fatty acids in patients with nonalcoholic fatty liver disease
- (2018) Kathy Musa-Veloso et al. NUTRITION REVIEWS
- Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma
- (2018) James S.V. Lally et al. Cell Metabolism
- Mitochondrial dysfunction-related lipid changes occur in non-alcoholic fatty liver disease progression
- (2018) Kang-Yu Peng et al. JOURNAL OF LIPID RESEARCH
- Of mice and men: Is there a future for metformin in the treatment of hepatic steatosis?
- (2018) Charlotte J. Green et al. DIABETES OBESITY & METABOLISM
- GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease
- (2018) Rohit Loomba et al. GASTROENTEROLOGY
- Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study
- (2017) L Hodson et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Acetyl-coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double-blind, crossover study
- (2017) Kathryn Stiede et al. HEPATOLOGY
- Chylomicron-Derived Fatty Acid Spillover in Adipose Tissue: A Signature of Metabolic Health?
- (2017) Marie-Eve Piché et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Treatment of NAFLD with diet, physical activity and exercise
- (2017) Manuel Romero-Gómez et al. JOURNAL OF HEPATOLOGY
- Zonation of hepatic fat accumulation: insights from mathematical modelling of nutrient gradients and fatty acid uptake
- (2017) Jana Schleicher et al. Journal of the Royal Society Interface
- SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology
- (2017) Hitoshi Shimano et al. Nature Reviews Endocrinology
- Cytosolic lipolysis and lipophagy: two sides of the same coin
- (2017) Rudolf Zechner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Withdrawal from high-carbohydrate, high-saturated-fat diet changes saturated fat distribution and improves hepatic low-density-lipoprotein receptor expression to ameliorate metabolic syndrome in rats
- (2017) Ankita Hazarika et al. NUTRITION
- Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance
- (2017) Maxwell A. Ruby et al. Cell Reports
- The Perilipins: Major Cytosolic Lipid Droplet–Associated Proteins and Their Roles in Cellular Lipid Storage, Mobilization, and Systemic Homeostasis
- (2016) Alan R. Kimmel et al. Annual Review of Nutrition
- The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders
- (2016) Sander M. Houten et al. Annual Review of Physiology
- Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by 13 C Magnetic Resonance Spectroscopy
- (2016) Kitt Falk Petersen et al. Cell Metabolism
- Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk
- (2016) Jennifer H. Stern et al. Cell Metabolism
- Fasting Plasma Insulin Concentrations Are Associated With Changes in Hepatic Fatty Acid Synthesis and Partitioning Prior to Changes in Liver Fat Content in Healthy Adults
- (2016) Camilla Pramfalk et al. DIABETES
- Pathophysiology of lipid droplet proteins in liver diseases
- (2016) Rotonya M. Carr et al. EXPERIMENTAL CELL RESEARCH
- Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice
- (2016) Satoshi Tanaka et al. HEPATOLOGY
- PML isoform II plays a critical role in nuclear lipid droplet formation
- (2016) Yuki Ohsaki et al. JOURNAL OF CELL BIOLOGY
- Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis
- (2016) Imanol Zubiete-Franco et al. JOURNAL OF HEPATOLOGY
- Non-alcoholic fatty liver disease and diabetes
- (2016) Jonathan M. Hazlehurst et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats
- (2016) Geraldine Harriman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caveolin-1 Function in Liver Physiology and Disease
- (2016) Manuel A. Fernandez-Rojo et al. TRENDS IN MOLECULAR MEDICINE
- Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review
- (2016) Tyler J Severson et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Roles of Acyl-CoA:Diacylglycerol Acyltransferases 1 and 2 in Triacylglycerol Synthesis and Secretion in Primary Hepatocytes
- (2015) C. Li et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- De novolipogenesis in the liver in health and disease: more than just a shunting yard for glucose
- (2015) Francis W. B. Sanders et al. BIOLOGICAL REVIEWS
- Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis
- (2015) Jonathan Y. Xia et al. Cell Metabolism
- Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis
- (2015) Chrysi Koliaki et al. Cell Metabolism
- Hepatic lipid droplet biology: Getting to the root of fatty liver
- (2015) Douglas G. Mashek et al. HEPATOLOGY
- Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
- (2015) Michal Pawlak et al. JOURNAL OF HEPATOLOGY
- Peroxisome-mitochondria interplay and disease
- (2015) Michael Schrader et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Recent insights into the biological functions of liver fatty acid binding protein 1
- (2015) GuQi Wang et al. JOURNAL OF LIPID RESEARCH
- Congenital generalized lipodystrophies—new insights into metabolic dysfunction
- (2015) Nivedita Patni et al. Nature Reviews Endocrinology
- Associations of sugar- and artificially sweetened soda with nonalcoholic fatty liver disease: a systematic review and meta-analysis
- (2015) K. Wijarnpreecha et al. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
- Effect of Fructose on Established Lipid Targets: A Systematic Review and Meta‐Analysis of Controlled Feeding Trials
- (2015) Laura Chiavaroli et al. Journal of the American Heart Association
- Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health: a systematic review and meta-analysis
- (2014) Mei Chung et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Higher fructose intake is inversely associated with risk of nonalcoholic fatty liver disease in older Finnish adults
- (2014) Noora Kanerva et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis
- (2014) Joseph J Lee et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Mature VLDL triggers the biogenesis of a distinct vesicle from thetrans-Golgi network for its export to the plasma membrane
- (2014) Tanvir Hossain et al. BIOCHEMICAL JOURNAL
- Metabolism of Very Long-Chain Fatty Acids: Genes and Pathophysiology
- (2014) Takayuki Sassa et al. Biomolecules & Therapeutics
- NOX2-generated oxidative stress is associated with severity of ultrasound liver steatosis in patients with non-alcoholic fatty liver disease
- (2014) Maria Del Ben et al. BMC GASTROENTEROLOGY
- CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance
- (2014) Suryaprakash Raichur et al. Cell Metabolism
- Overfeeding Polyunsaturated and Saturated Fat Causes Distinct Effects on Liver and Visceral Fat Accumulation in Humans
- (2014) F. Rosqvist et al. DIABETES
- Effect of fructose on markers of non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of controlled feeding trials
- (2014) S Chiu et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells
- (2014) Alexandra K. Leamy et al. JOURNAL OF LIPID RESEARCH
- Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism
- (2014) Chi-Liang Eric Yen et al. JOURNAL OF LIPID RESEARCH
- TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content
- (2014) H. Mahdessian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recent insights into the molecular pathophysiology of lipid droplet formation in hepatocytes
- (2014) Nishika Sahini et al. PROGRESS IN LIPID RESEARCH
- Histopathology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
- (2014) Yoshihisa Takahashi WORLD JOURNAL OF GASTROENTEROLOGY
- The Role of Dietary Sugars and De novo Lipogenesis in Non-Alcoholic Fatty Liver Disease
- (2014) J. Moore et al. Nutrients
- Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease
- (2013) Jennifer E. Lambert et al. GASTROENTEROLOGY
- Perilipin discerns chronic from acute hepatocellular steatosis
- (2013) Lena Maria Pawella et al. JOURNAL OF HEPATOLOGY
- Assessment of hepatic steatosis by transplant surgeon and expert pathologist: A prospective, double-blind evaluation of 201 donor livers
- (2013) Hasan Yersiz et al. LIVER TRANSPLANTATION
- Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
- (2013) Quentin M. Anstee et al. Nature Reviews Gastroenterology & Hepatology
- The Lipid Droplet as a Potential Therapeutic Target in NAFLD
- (2013) Vera Goh et al. SEMINARS IN LIVER DISEASE
- Novel insights into ChREBP regulation and function
- (2013) Gaëlle Filhoulaud et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Hepatic Fatty Acid Trafficking: Multiple Forks in the Road
- (2013) Douglas G. Mashek Advances in Nutrition
- Lumenal Lipid Metabolism
- (2012) Richard Lehner et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Intracellular Trafficking and Secretion of VLDL
- (2012) Samata Tiwari et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
- (2012) Rudolf Zechner et al. Cell Metabolism
- Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease
- (2012) Hae-Ki Min et al. Cell Metabolism
- Whole-body substrate metabolism is associated with disease severity in patients with non-alcoholic fatty liver disease
- (2012) Ilaria Croci et al. GUT
- Malonyl-CoA: the regulator of fatty acid synthesis and oxidation
- (2012) Daniel W. Foster JOURNAL OF CLINICAL INVESTIGATION
- Seipin: from human disease to molecular mechanism
- (2012) Bethany R. Cartwright et al. JOURNAL OF LIPID RESEARCH
- Fructose metabolism in humans – what isotopic tracer studies tell us
- (2012) Sam Z Sun et al. Nutrition & Metabolism
- LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease
- (2012) Veerle Bieghs et al. PLoS One
- Distinct roles for α-β hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling
- (2012) Caleb C. Lord et al. Adipocyte
- Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease
- (2011) Nishanth E. Sunny et al. Cell Metabolism
- Hepatic fatty acid partitioning
- (2011) Leanne Hodson et al. CURRENT OPINION IN LIPIDOLOGY
- Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation
- (2011) F. Karpe et al. DIABETES
- Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and women
- (2011) C L Cox et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Expression of Perilipin and Adipophilin in Nonalcoholic Fatty Liver Disease; Relevance to Oxidative Injury and Hepatocyte Ballooning
- (2011) Hideki Fujii et al. Journal of Atherosclerosis and Thrombosis
- Role of lipid droplet proteins in liver steatosis
- (2011) Toshikatsu Okumura JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease
- (2011) NOBITO HIGUCHI et al. Experimental and Therapeutic Medicine
- Fructose containing sugars modulate mRNA of lipogenic genes ACC and FAS and protein levels of transcription factors ChREBP and SREBP1c with no effect on body weight or liver fat
- (2011) Mile Janevski et al. Food & Function
- Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?
- (2010) Leanne Hodson et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation
- (2010) Donald B. Jump et al. BIOCHEMICAL PHARMACOLOGY
- Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C
- (2010) Elena Lima-Cabello et al. CLINICAL SCIENCE
- Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?
- (2010) S. E. McQuaid et al. DIABETES
- Effects of short-term overfeeding with fructose, fat and fructose plus fat on plasma and hepatic lipids in healthy men
- (2010) H. Sobrecases et al. DIABETES & METABOLISM
- Fatty Acid Metabolism in the Liver, Measured by Positron Emission Tomography, Is Increased in Obese Individuals
- (2010) Patricia Iozzo et al. GASTROENTEROLOGY
- Long-term mortality in nonalcoholic fatty liver disease: Is liver histology of any prognostic significance?
- (2010) Paul Angulo HEPATOLOGY
- Presence and significance of microvesicular steatosis in nonalcoholic fatty liver disease
- (2010) Sweta Tandra et al. JOURNAL OF HEPATOLOGY
- Increased adipose tissue lipolysis after a 2-week high-fat diet in sedentary overweight/obese men
- (2010) Harold R. Howe et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Lipid in the livers of adolescents with nonalcoholic steatohepatitis: combined effects of pathways on steatosis
- (2010) Lixin Zhu et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes
- (2009) Kim-Anne Lê et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Synthesis of specific fatty acids contributes to VLDL-triacylglycerol composition in humans with and without type 2 diabetes
- (2009) M. S. Wilke et al. DIABETOLOGIA
- Differential expression of lumican and fatty acid binding protein-1: New insights into the histologic spectrum of nonalcoholic fatty liver disease
- (2009) Michael Charlton et al. HEPATOLOGY
- Omega-3 Fatty Acid Supplementation Decreases Liver Fat Content in Polycystic Ovary Syndrome: A Randomized Controlled Trial Employing Proton Magnetic Resonance Spectroscopy
- (2009) Andrea J. Cussons et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Fasted to Fed Trafficking of Fatty Acids in Human Adipose Tissue Reveals a Novel Regulatory Step for Enhanced Fat Storage
- (2009) Toralph Ruge et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Highly Purified Eicosapentaenoic Acid Treatment Improves Nonalcoholic Steatohepatitis
- (2009) Naoki Tanaka et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans
- (2009) Kimber L. Stanhope et al. JOURNAL OF CLINICAL INVESTIGATION
- Liver fat and lipid oxidation in humans
- (2009) Anna Kotronen et al. LIVER INTERNATIONAL
- Autophagy regulates lipid metabolism
- (2009) Rajat Singh et al. NATURE
- Gene expression in human NAFLD
- (2008) Dario Greco et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Overproduction of Very Low–Density Lipoproteins Is the Hallmark of the Dyslipidemia in the Metabolic Syndrome
- (2008) Martin Adiels et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition
- (2008) Tal M. Lewin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Differential pattern of lipid droplet-associated proteins andde novoperilipin expression in hepatocyte steatogenesis
- (2008) Beate Katharina Straub et al. HEPATOLOGY
- Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
- (2008) Nobito Higuchi et al. HEPATOLOGY RESEARCH
- Liver lipid metabolism
- (2008) P. Nguyen et al. JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
- Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100
- (2008) Y. Ohsaki et al. JOURNAL OF CELL SCIENCE
- The evolution of plasma cholesterol: Direct utility or a “spandrel” of hepatic lipid metabolism?
- (2008) Patrick J. Babin et al. PROGRESS IN LIPID RESEARCH
- Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis
- (2007) Jie Zhou et al. GASTROENTEROLOGY
- Alterations in Adipose Tissue and Hepatic Lipid Kinetics in Obese Men and Women With Nonalcoholic Fatty Liver Disease
- (2007) Elisa Fabbrini et al. GASTROENTEROLOGY
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