Real-Time 3D Single Particle Tracking: Towards Active Feedback Single Molecule Spectroscopy in Live Cells

Multicolor Three-Dimensional Tracking for Single-Molecule Fluorescence Resonance Energy Transfer Measurements

(2018) Aaron M. Keller et al.   ANALYTICAL CHEMISTRY

A Protocol for Real-time 3D Single Particle Tracking

(2018) Shangguo Hou et al.   Jove-Journal of Visualized Experiments

Recording Neural Activity in Unrestrained Animals with Three-Dimensional Tracking Two-Photon Microscopy

(2018) Doycho Karagyozov et al.   Cell Reports

3D single-molecule tracking enables direct hybridization kinetics measurement in solution

(2017) Cong Liu et al.   Nanoscale

Adaptive optical fluorescence microscopy

(2017) Na Ji   NATURE METHODS

Robust real-time 3D single-particle tracking using a dynamically moving laser spot

(2017) Shangguo Hou et al.   OPTICS LETTERS

Extended depth-of-field microscopy with a high-speed deformable mirror

(2017) William J. Shain et al.   OPTICS LETTERS

Studying transcription initiation by RNA polymerase with diffusion-based single-molecule fluorescence

(2017) Yazan Alhadid et al.   PROTEIN SCIENCE

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength

(2016) Ruhma Syeda et al.   CELL

Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles

(2016) Merja Joensuu et al.   JOURNAL OF CELL BIOLOGY

Three-dimensional particle tracking via tunable color-encoded multiplexing

(2016) Martí Duocastella et al.   OPTICS LETTERS

Probing the kinetic and thermodynamic consequences of the tetraloop/tetraloop receptor monovalent ion-binding site in P4–P6 RNA by smFRET

(2015) Namita Bisaria et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Super-resolution imaging for cell biologists

(2015) Eugenio F. Fornasiero et al.   BIOESSAYS

Single-Molecule Identification of Quenched and Unquenched States of LHCII

(2015) Gabriela S. Schlau-Cohen et al.   Journal of Physical Chemistry Letters

The 2015 super-resolution microscopy roadmap

(2015) Stefan W Hell et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Imaging Live-Cell Dynamics and Structure at the Single-Molecule Level

(2015) Zhe Liu et al.   MOLECULAR CELL

Precise Three-Dimensional Scan-Free Multiple-Particle Tracking over Large Axial Ranges with Tetrapod Point Spread Functions

(2015) Yoav Shechtman et al.   NANO LETTERS

Lens-based fluorescence nanoscopy

(2015) Christian Eggeling et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Note: Time-gated 3D single quantum dot tracking with simultaneous spinning disk imaging

(2015) M. S. DeVore et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination

(2015) Evan P. Perillo et al.   Nature Communications

Real-time submillisecond single-molecule FRET dynamics of freely diffusing molecules with liposome tethering

(2015) Jae-Yeol Kim et al.   Nature Communications

Electrically tunable lens speeds up 3D orbital tracking

(2015) Paolo Annibale et al.   Biomedical Optics Express

Superresolution Imaging of Biological Systems Using Photoactivated Localization Microscopy

(2014) Prabuddha Sengupta et al.   CHEMICAL REVIEWS

In vivo single-molecule imaging of bacterial DNA replication, transcription, and repair

(2014) Mathew Stracy et al.   FEBS LETTERS

Tracking single molecules at work in living cells

(2014) Akihiro Kusumi et al.   Nature Chemical Biology

Multi-resolution 3D visualization of the early stages of cellular uptake of peptide-coated nanoparticles

(2014) Kevin Welsher et al.   Nature Nanotechnology

Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking

(2014) Jan-Hendrik Spille et al.   NUCLEIC ACIDS RESEARCH

Three-dimensional tracking of a single fluorescent nanoparticle using four-focus excitation in a confocal microscope

(2014) James A. Germann et al.   OPTICS EXPRESS

Orbital single particle tracking on a commercial confocal microscope using piezoelectric stage feedback

(2014) L Lanzanò et al.   Methods and Applications in Fluorescence

Quantitative Imaging of Transcription in Living Drosophila Embryos Links Polymerase Activity to Patterning

(2013) Hernan G. Garcia et al.   CURRENT BIOLOGY

Single-molecule spectroscopy of protein folding dynamics—expanding scope and timescales

(2013) Benjamin Schuler et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Seeing the forest tree by tree: super-resolution light microscopy meets the neurosciences

(2013) Marta Maglione et al.   NATURE NEUROSCIENCE

Bacterial replication, transcription and translation: mechanistic insights from single-molecule biochemical studies

(2013) Andrew Robinson et al.   NATURE REVIEWS MICROBIOLOGY

Three-dimensional single-particle tracking in live cells: news from the third dimension

(2013) A Dupont et al.   NEW JOURNAL OF PHYSICS

Single-molecule spectroscopy reveals photosynthetic LH2 complexes switch between emissive states

(2013) G. S. Schlau-Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Harnessing thermal fluctuations for purposeful activities: the manipulation of single micro-swimmers by adaptive photon nudging

(2013) Bian Qian et al.   Chemical Science

Three-Dimensional Tracking of Carbon Nanotubes within Living Cells

(2012) Nigel F. Reuel et al.   ACS Nano

Time-Resolved, Confocal Single-Molecule Tracking of Individual Organic Dyes and Fluorescent Proteins in Three Dimensions

(2012) Jason J. Han et al.   ACS Nano

Quantum dot-DNA origami binding: a single particle, 3D, real-time tracking study

(2012) Kan Du et al.   CHEMICAL COMMUNICATIONS

Simultaneous imaging of multiple focal planes for three-dimensional microscopy using ultra-high-speed adaptive optics

(2012) Martí Duocastella et al.   JOURNAL OF BIOMEDICAL OPTICS

Three-Dimensional Real-Time Tracking of Nanoparticles at an Oil–Water Interface

(2012) Kan Du et al.   LANGMUIR

Differential Motion Dynamics of Synaptic Vesicles Undergoing Spontaneous and Activity-Evoked Endocytosis

(2012) Amy Peng et al.   NEURON

Optimal tracking of a Brownian particle

(2012) Alexander P. Fields et al.   OPTICS EXPRESS

Single-molecule FRET reveals nucleotide-driven conformational changes in molecular machines and their link to RNA unwinding and DNA supercoiling

(2011) Dagmar Klostermeier   BIOCHEMICAL SOCIETY TRANSACTIONS

Corkscrew point spread function for far-field three-dimensional nanoscale localization of pointlike objects

(2011) Matthew D. Lew et al.   OPTICS LETTERS

Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window

(2011) K. Welsher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Convex Lens-Induced Confinement for Imaging Single Molecules

(2010) Sabrina R. Leslie et al.   ANALYTICAL CHEMISTRY

Mobility of Cytoplasmic, Membrane, and DNA-Binding Proteins in Escherichia coli

(2010) Mohit Kumar et al.   BIOPHYSICAL JOURNAL

Three-Dimensional Tracking of Single Fluorescent Particles with Submillisecond Temporal Resolution

(2010) Manuel F. Juette et al.   NANO LETTERS

Time-Resolved Three-Dimensional Molecular Tracking in Live Cells

(2010) Nathan P. Wells et al.   NANO LETTERS

Watching conformational- and photodynamics of single fluorescent proteins in solution

(2010) Randall H. Goldsmith et al.   Nature Chemistry

Going deeper than microscopy: the optical imaging frontier in biology

(2010) Vasilis Ntziachristos   NATURE METHODS

Optimal strategy for trapping single fluorescent molecules in solution using the ABEL trap

(2009) Q. Wang et al.   APPLIED PHYSICS B-LASERS AND OPTICS

Real-Time Nanomicroscopy via Three-Dimensional Single-Particle Tracking

(2009) Yoshihiko Katayama et al.   CHEMPHYSCHEM

Single-molecule observations of ribosome function

(2009) Scott C Blanchard   CURRENT OPINION IN STRUCTURAL BIOLOGY

Precise Characterization of the Conformation Fluctuations of Freely Diffusing DNA: Beyond Rouse and Zimm

(2009) Kevin McHale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice

(2009) Kevin Welsher et al.   Nature Nanotechnology

Interplay of  -synuclein binding and conformational switching probed by single-molecule fluorescence

(2009) A. C. M. Ferreon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function

(2009) S. R. P. Pavani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Confocal, Three-Dimensional Tracking of Individual Quantum Dots in High-Background Environments

(2008) Nathan P. Wells et al.   ANALYTICAL CHEMISTRY

Observation of spectral anisotropy of gold nanoparticles

(2008) Hu Cang et al.   JOURNAL OF CHEMICAL PHYSICS

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS

Controlling Brownian motion of single protein molecules and single fluorophores in aqueous buffer

(2008) Adam E. Cohen et al.   OPTICS EXPRESS

High-speed varifocal imaging with a tunable acoustic gradient index of refraction lens

(2008) Alexandre Mermillod-Blondin et al.   OPTICS LETTERS