Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity

The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo.

(2018) Matthew A Odenwald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Claudin-4 reconstituted in unilamellar vesicles is sufficient to form tight interfaces that partition membrane proteins

(2018) Brian Belardi et al.   JOURNAL OF CELL SCIENCE

An apical MRCK-driven morphogenetic pathway controls epithelial polarity

(2017) Ceniz Zihni et al.   NATURE CELL BIOLOGY

Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells

(2017) Shinsaku Tokuda et al.   PLoS One

The Par3 polarity protein is an exocyst receptor essential for mammary cell survival

(2017) Syed Mukhtar Ahmed et al.   Nature Communications

Remodeling the zonula adherens in response to tension and the role of afadin in this response

(2016) Wangsun Choi et al.   JOURNAL OF CELL BIOLOGY

DAAM1 stabilizes epithelial junctions by restraining WAVE complex–dependent lateral membrane motility

(2016) Tamako Nishimura et al.   JOURNAL OF CELL BIOLOGY

ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture

(2016) Matthew A. Odenwald et al.   JOURNAL OF CELL SCIENCE

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells

(2015) Priyank Shukla et al.   BMC GENOMICS

Claudin-2 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Claudin-2 Independently Determines the Leaky Property of Tight Junctions in MDCK Cells

(2015) Shinsaku Tokuda et al.   PLoS One

JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis

(2015) Hüseyin Tuncay et al.   Nature Communications

ZO-1 and ZO-2 Are Required for Extra-Embryonic Endoderm Integrity, Primitive Ectoderm Survival and Normal Cavitation in Embryoid Bodies Derived from Mouse Embryonic Stem Cells

(2014) Dominic C. Y. Phua et al.   PLoS One

ZO-1 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Involvement of ZO-1 in the Regulation of Cytoskeleton and Cell Shape

(2014) Shinsaku Tokuda et al.   PLoS One

Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux

(2013) Mary M. Buschmann et al.   MOLECULAR BIOLOGY OF THE CELL

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

Nectins localize Willin to cell-cell junctions

(2012) Takashi Ishiuchi et al.   GENES TO CELLS

Lipid Polarity Is Maintained in Absence of Tight Junctions

(2012) Junichi Ikenouchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation

(2012) Sandra Iden et al.   JOURNAL OF CELL BIOLOGY

Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-Myosin II signaling

(2012) M. Itoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier

(2011) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tight Junction Pore and Leak Pathways: A Dynamic Duo

(2011) Le Shen et al.   Annual Review of Physiology

Cadherin–actin interactions at adherens junctions

(2011) Shigenobu Yonemura   CURRENT OPINION IN CELL BIOLOGY

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia

(2011) Alan S. Fanning et al.   MOLECULAR BIOLOGY OF THE CELL

Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation

(2011) Takashi Ishiuchi et al.   NATURE CELL BIOLOGY

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Tricellulin Forms a Barrier to Macromolecules in Tricellular Tight Junctions without Affecting Ion Permeability

(2009) Susanne M. Krug et al.   MOLECULAR BIOLOGY OF THE CELL

ZO-1 Stabilizes the Tight Junction Solute Barrier through Coupling to the Perijunctional Cytoskeleton

(2009) Christina M. Van Itallie et al.   MOLECULAR BIOLOGY OF THE CELL

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

ZO-1- and ZO-2-Dependent Integration of Myosin-2 to Epithelial Zonula Adherens

(2008) Yuji Yamazaki et al.   MOLECULAR BIOLOGY OF THE CELL