MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer

miR200-regulated CXCL12β promotes fibroblast heterogeneity and immunosuppression in ovarian cancers

(2018) Anne-Marie Givel et al.   Nature Communications

Let-7b inhibits cancer-promoting effects of breast cancer-associated fibroblasts through IL-8 repression

(2018) Bothina Al-Harbi et al.   Oncotarget

miR-539 acts as a tumor suppressor by targeting epidermal growth factor receptor in breast cancer

(2018) Jilong Guo et al.   Scientific Reports

Senescence-associated microRNAs target cell cycle regulatory genes in normal human lung fibroblasts

(2017) Georgios S. Markopoulos et al.   EXPERIMENTAL GERONTOLOGY

MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists

(2017) Cong Lv et al.   Nature Communications

MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling

(2017) Yan-e Du et al.   Theranostics

Loss of lamin B receptor is necessary to induce cellular senescence

(2016) Emilie Lukášová et al.   BIOCHEMICAL JOURNAL

Tumor microenvironment: The culprit for ovarian cancer metastasis?

(2016) Zhongyue Luo et al.   CANCER LETTERS

miR-222 confers the resistance of breast cancer cells to Adriamycin through suppression of p27kip1 expression

(2016) Dan-dan Wang et al.   GENE

Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts

(2016) S Baroni et al.   Cell Death & Disease

Heterotypic paracrine signaling drives fibroblast senescence and tumor progression of large cell carcinoma of the lung

(2016) Roberto Lugo et al.   Oncotarget

Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling

(2015) X Tang et al.   CELL DEATH AND DIFFERENTIATION

miR-221 and miR-222 Simultaneously Target RECK and Regulate Growth and Invasion of Gastric Cancer Cells

(2015) Wenneng Liu et al.   MEDICAL SCIENCE MONITOR

Down-Regulation of mir-221 and mir-222 Restrain Prostate Cancer Cell Proliferation and Migration That Is Partly Mediated by Activation of SIRT1

(2014) Xiao Yang et al.   PLoS One

Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth

(2014) Ubaldo E. Martinez-Outschoorn et al.   SEMINARS IN CANCER BIOLOGY

Increased expression of miR-222 is associated with poor prognosis in bladder cancer

(2014) Dong-qing Zhang et al.   World Journal of Surgical Oncology

Targeting the Tumor Microenvironment: From Understanding Pathways to Effective Clinical Trials

(2013) H. Fang et al.   CANCER RESEARCH

Breast cancer as a systemic disease: a view of metastasis

(2013) A. J. Redig et al.   JOURNAL OF INTERNAL MEDICINE

MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion

(2013) Eldo T Verghese et al.   JOURNAL OF PATHOLOGY

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

MicroRNA-21 in Pancreatic Ductal Adenocarcinoma Tumor-Associated Fibroblasts Promotes Metastasis

(2013) Brian E. Kadera et al.   PLoS One

miR-222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27kip1

(2013) CHAOYANG SUN et al.   Oncology Letters

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression

(2012) E. Josephine Clowney et al.   CELL

MiRNA expression analysis of cancer-associated fibroblasts and normal fibroblasts in breast cancer

(2012) Liuyang Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ

(2011) C Quintavalle et al.   ONCOGENE

MicroRegulators come of age in senescence

(2011) Myriam Gorospe et al.   TRENDS IN GENETICS

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Cancer-associated fibroblasts and tumor growth – bystanders turning into key players

(2009) Arne Östman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT