Cell-Free Culture Supernatant of Probiotic Lactobacillus fermentum Protects Against H2O2-Induced Premature Senescence by Suppressing ROS-Akt-mTOR Axis in Murine Preadipocytes

Diet supplemented with phytochemical epigallocatechin gallate and probiotic Lactobacillus fermentum confers second generation synbiotic effects by modulating cellular immune responses and antioxidant capacity in aging mice

(2019) Rohit Sharma et al.   EUROPEAN JOURNAL OF NUTRITION

Probiotic Cell-Free Supernatants Exhibited Anti-Inflammatory and Antioxidant Activity on Human Gut Epithelial Cells and Macrophages Stimulated with LPS

(2018) Stefania De Marco et al.   Evidence-based Complementary and Alternative Medicine

Benefaction of probiotics for human health: A review

(2018) Rout George Kerry et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Lactobacillus plantarum Strain Ln4 Attenuates Diet-Induced Obesity, Insulin Resistance, and Changes in Hepatic mRNA Levels Associated with Glucose and Lipid Metabolism

(2018) Eunjung Lee et al.   Nutrients

Redox Role of Lactobacillus casei Shirota Against the Cellular Damage Induced by 2,2′-Azobis (2-Amidinopropane) Dihydrochloride-Induced Oxidative and Inflammatory Stress in Enterocytes-Like Epithelial Cells

(2018) Alberto Finamore et al.   Frontiers in Immunology

Prunus cerasoides fruit extract ameliorates inflammatory stress by modulation of iNOS pathway and Th1/Th2 immune homeostasis in activated murine macrophages and lymphocytes

(2018) Anamika Sharma et al.   INFLAMMOPHARMACOLOGY

Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation of Bax/Bcl-2 pathway

(2018) Ravi Kumar et al.   BIOGERONTOLOGY

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health

(2017) et al.   Nutrients

Antioxidant Properties of Probiotic Bacteria

(2017) Yang Wang et al.   Nutrients

Probiotic Bacteria for Healthier Aging: Immunomodulation and Metabolism of Phytoestrogens

(2017) José María Landete et al.   Biomed Research International

Lactic acid bacteria-specific induction of CD4+Foxp3+T cells ameliorates shrimp tropomyosin-induced allergic response in mice via suppression of mTOR signaling

(2017) Linglin Fu et al.   Scientific Reports

The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging

(2016) Brian K. Kennedy et al.   Cell Metabolism

Finding Shangri-La: Limiting the Impact of Senescence on Aging

(2016) Sally E. Trabucco et al.   Cell Stem Cell

Metformin Is Associated With Higher Relative Abundance of Mucin-DegradingAkkermansia muciniphilaand Several Short-Chain Fatty Acid–Producing Microbiota in the Gut

(2016) Jacobo de la Cuesta-Zuluaga et al.   DIABETES CARE

A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses

(2016) Eric H. Bent et al.   GENES & DEVELOPMENT

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization

(2016) Michael B. Stout et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

Cellular Senescence as the Causal Nexus of Aging

(2016) Naina Bhatia-Dey et al.   Frontiers in Genetics

Aberrant mTOR activation in senescence and aging: A mitochondrial stress response?

(2015) Timothy Nacarelli et al.   EXPERIMENTAL GERONTOLOGY

Analytical approaches to the diagnosis and treatment of aging and aging-related disease: redox status and proteomics

(2015) V. Calabrese et al.   FREE RADICAL RESEARCH

Probiotics as Potential Antioxidants: A Systematic Review

(2015) Vijendra Mishra et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lactobacillus pentosusvar.plantarumC29 ameliorates age-dependent memory impairment in Fischer 344 rats

(2015) J.-J. Jeong et al.   LETTERS IN APPLIED MICROBIOLOGY

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

(2015) Remi-Martin Laberge et al.   NATURE CELL BIOLOGY

Orally Administrated Lactobacillus pentosus var. plantarum C29 Ameliorates Age-Dependent Colitis by Inhibiting the Nuclear Factor-Kappa B Signaling Pathway via the Regulation of Lipopolysaccharide Production by Gut Microbiota

(2015) Jin-Ju Jeong et al.   PLoS One

Specialized Metabolites from the Microbiome in Health and Disease

(2014) Gil Sharon et al.   Cell Metabolism

Molecular mechanisms for the p38-induced cellular senescence in normal human fibroblast

(2014) Gakuro Harada et al.   JOURNAL OF BIOCHEMISTRY

Dietary supplementation of milk fermented with probiotic Lactobacillus fermentum enhances systemic immune response and antioxidant capacity in aging mice

(2014) Rohit Sharma et al.   NUTRITION RESEARCH

Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence

(2014) Yingxi Xu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

(2014) Diana Jurk et al.   Nature Communications

Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia coli-mediated inflammation

(2013) Naoya Takanashi et al.   BMC MICROBIOLOGY

Probiotics as Anti-immunosenescence Agents

(2013) Rohit Sharma et al.   FOOD REVIEWS INTERNATIONAL

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

Lactobacillus plantarumLG42 Isolated from Gajami Sik-Hae Inhibits Adipogenesis in 3T3-L1 Adipocyte

(2013) Jeong-Eun Park et al.   Biomed Research International

Nuclear lamina defects cause ATM-dependent NF- B activation and link accelerated aging to a systemic inflammatory response

(2012) F. G. Osorio et al.   GENES & DEVELOPMENT

Lactobacillus casei Extract Induces Apoptosis in Gastric Cancer by Inhibiting NF-κB and mTOR-Mediated Signaling

(2012) Jeong Won Hwang et al.   INTEGRATIVE CANCER THERAPIES

Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation

(2012) Peera Hemarajata et al.   Therapeutic Advances in Gastroenterology

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

(2011) Antero Salminen et al.   CELLULAR SIGNALLING

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

Probiotics in the gastrointestinal diseases of the elderly

(2011) G. Malaguarnera et al.   Journal of Nutrition Health & Aging

Aging: ROS or TOR

(2010) Mikhail V Blagosklonny   CELL CYCLE

Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program

(2010) Mikhail V Blagosklonny   CELL CYCLE

In vitro aging of 3T3-L1 mouse adipocytes leads to altered metabolism and response to inflammation

(2009) Elena Zoico et al.   BIOGERONTOLOGY

An Update of the Oxidation-Inflammation Theory of Aging: The Involvement of the Immune System in Oxi-Inflamm-Aging

(2009) Monica Fuente et al.   CURRENT PHARMACEUTICAL DESIGN

Probiotics: Delineation of Prophylactic and Therapeutic Benefits

(2009) Indu Pal Kaur et al.   JOURNAL OF MEDICINAL FOOD

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL