The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways
出版年份 2019 全文链接
标题
The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways
作者
关键词
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出版物
Scientific Reports
Volume 9, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-07-01
DOI
10.1038/s41598-019-45817-5
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- FKS2 and FKS3 Genes of Opportunistic Human Pathogen Candida albicans Influence Echinocandin Susceptibility
- (2018) Sumanun Suwunnakorn et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Gcn5-dependent histone H3 acetylation and gene activity is required for the asexual development and virulence of Beauveria bassiana
- (2018) Qing Cai et al. ENVIRONMENTAL MICROBIOLOGY
- The antifungal arsenal: alternative drugs and future targets
- (2018) Nathan P. Wiederhold INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Epigenetic Control of Oxidative Stresses by Histone Acetyltransferases in Candida albicans
- (2018) Jueun Kim et al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
- Dynamic Fungal Cell Wall Architecture in Stress Adaptation and Immune Evasion
- (2018) Alex Hopke et al. TRENDS IN MICROBIOLOGY
- Invasive candidiasis
- (2018) Peter G. Pappas et al. Nature Reviews Disease Primers
- The burden of invasive infections in neutropenic patients: incidence, outcomes, and use of granulocyte transfusions (Editorial, p. 6)
- (2018) Tanja Netelenbos et al. TRANSFUSION
- Histone acetyltransferase encoded by NGG1 is required for morphological conversion and virulence of Candida albicans
- (2017) De-Dong Li et al. Future Microbiology
- Candida auris : an Emerging Fungal Pathogen
- (2017) Emily S. Spivak et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment
- (2017) Maiken Cavling Arendrup et al. JOURNAL OF INFECTIOUS DISEASES
- Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi
- (2017) Matthew W McCarthy et al. JOURNAL OF INFECTIOUS DISEASES
- The global problem of antifungal resistance: prevalence, mechanisms, and management
- (2017) David S Perlin et al. LANCET INFECTIOUS DISEASES
- Development and regulation of single- and multi-species Candida albicans biofilms
- (2017) Matthew B. Lohse et al. NATURE REVIEWS MICROBIOLOGY
- The Iron-Dependent Regulation of the Candida albicans Oxidative Stress Response by the CCAAT-Binding Factor
- (2017) Ananya Chakravarti et al. PLoS One
- Functional analysis of the MAPK pathways in fungi
- (2017) Domingo Martínez-Soto et al. REVISTA IBEROAMERICANA DE MICOLOGIA
- Sharing the SAGA
- (2017) Dominique Helmlinger et al. TRENDS IN BIOCHEMICAL SCIENCES
- Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally
- (2017) Anuradha Chowdhary et al. PLoS Pathogens
- Antifungal resistance: current trends and future strategies to combat
- (2017) Nathan Wiederhold Infection and Drug Resistance
- Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota
- (2016) Sarah Höfs et al. JOURNAL OF MICROBIOLOGY
- The Mechanistic Targets of Antifungal Agents: An Overview
- (2016) Tryphon K. Mazu et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Extensive functional redundancy in the regulation ofCandida albicansdrug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31
- (2016) Xinliu Li et al. MOLECULAR MICROBIOLOGY
- The molecular hallmarks of epigenetic control
- (2016) C. David Allis et al. NATURE REVIEWS GENETICS
- Candida albicans cell-type switching and functional plasticity in the mammalian host
- (2016) Suzanne M. Noble et al. NATURE REVIEWS MICROBIOLOGY
- A Class 1 Histone Deacetylase with Potential as an Antifungal Target
- (2016) Ingo Bauer et al. mBio
- The Paralogous Histone Deacetylases Rpd3 and Rpd31 Play Opposing Roles in Regulating the White-Opaque Switch in the Fungal Pathogen Candida albicans
- (2016) Jing Xie et al. mBio
- N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
- (2016) Chang Su et al. Nature Communications
- Unmasking fungal pathogens by studying MAPK-dependent cell wall regulation inCandida albicans
- (2016) Paul J. Cullen et al. Virulence
- Fungal KATs/KDACs: A New Highway to Better Antifungal Drugs?
- (2016) Karl Kuchler et al. PLoS Pathogens
- Histone Deacetylases and Their Inhibition in Candida Species
- (2016) Cécile Garnaud et al. Frontiers in Microbiology
- Crystal violet staining to quantify Candida adhesion to epithelial cells
- (2016) M. Negri et al. BRITISH JOURNAL OF BIOMEDICAL SCIENCE
- Mechanisms of echinocandin antifungal drug resistance
- (2015) David S. Perlin Annals of the New York Academy of Sciences
- Multidrug Transporters and Alterations in Sterol Biosynthesis Contribute to Azole Antifungal Resistance in Candida parapsilosis
- (2015) Elizabeth L. Berkow et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species
- (2015) M.A. Pfaller et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
- Function and subcellular localization of Gcn5, a histone acetyltransferase in Candida albicans
- (2015) Peng Chang et al. FUNGAL GENETICS AND BIOLOGY
- Using combination therapy to thwart drug resistance
- (2015) Jessica A Hill et al. Future Microbiology
- Gcn5 Modulates the Cellular Response to Oxidative Stress and Histone Deacetylase Inhibition
- (2015) Ann-Christin Gaupel et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance
- (2015) Iuliana V. Ene et al. mBio
- Adaptive immune responses toCandida albicansinfection
- (2015) Jonathan P Richardson et al. Virulence
- The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways
- (2015) Michael Tscherner et al. PLoS Pathogens
- Host-pathogen interactions between the human innate immune system and Candida albicans—understanding and modeling defense and evasion strategies
- (2015) Sybille Dühring et al. Frontiers in Microbiology
- Histone deacetylase inhibition as an alternative strategy against invasive aspergillosis
- (2015) Frédéric Lamoth et al. Frontiers in Microbiology
- UPC2AIs Required for High-Level Azole Antifungal Resistance in Candida glabrata
- (2014) Sarah G. Whaley et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- SAGA/ADA Complex Subunit Ada2 Is Required for Cap1- but Not Mrr1-Mediated Upregulation of the Candida albicans Multidrug Efflux PumpMDR1
- (2014) Bernardo Ramírez-Zavala et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- FungiFun2: a comprehensive online resource for systematic analysis of gene lists from fungal species
- (2014) S. Priebe et al. BIOINFORMATICS
- UPC2 Is Universally Essential for Azole Antifungal Resistance in Candida albicans
- (2014) Erin M. Vasicek et al. EUKARYOTIC CELL
- The lack of upstream elements of the Cek1 and Hog1 mediated pathways leads to a synthetic lethal phenotype upon osmotic stress in Candida albicans
- (2014) Carmen Herrero-de-Dios et al. FUNGAL GENETICS AND BIOLOGY
- The UmGcn5 gene encoding histone acetyltransferase from Ustilago maydis is involved in dimorphism and virulence
- (2014) Juan Manuel González-Prieto et al. FUNGAL GENETICS AND BIOLOGY
- The Histone Acetyltransferase GcnE (GCN5) Plays a Central Role in the Regulation of Aspergillus Asexual Development
- (2014) David Cánovas et al. GENETICS
- The Bromodomain of Gcn5 Regulates Site Specificity of Lysine Acetylation on Histone H3
- (2014) Anne M. Cieniewicz et al. MOLECULAR & CELLULAR PROTEOMICS
- Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense
- (2014) Gerald Wirnsberger et al. NATURE GENETICS
- The Non-receptor Tyrosine Kinase Tec Controls Assembly and Activity of the Noncanonical Caspase-8 Inflammasome
- (2014) Florian Zwolanek et al. PLoS Pathogens
- A Relay Network of Extracellular Heme-Binding Proteins Drives C. albicans Iron Acquisition from Hemoglobin
- (2014) Galit Kuznets et al. PLoS Pathogens
- Epidemiology and risk factors for invasive candidiasis
- (2014) Nur Yapar Therapeutics and Clinical Risk Management
- Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome
- (2013) Yongtao Xue-Franzén et al. BMC GENOMICS
- Distinct and Redundant Roles of the Two MYST Histone Acetyltransferases Esa1 and Sas2 in Cell Growth and Morphogenesis of Candida albicans
- (2013) Xiongjun Wang et al. EUKARYOTIC CELL
- Adhesins in Human Fungal Pathogens: Glue with Plenty of Stick
- (2013) Piet W. J. de Groot et al. EUKARYOTIC CELL
- Distinct Roles of Candida albicans Drug Resistance Transcription Factors TAC1 , MRR1 , and UPC2 in Virulence
- (2013) Andrea Lohberger et al. EUKARYOTIC CELL
- Transcription factors spt3 and spt8 are associated with conidiation, mycelium growth, and pathogenicity inFusarium graminearum
- (2013) Tao Gao et al. FEMS MICROBIOLOGY LETTERS
- Stress adaptation in a pathogenic fungus
- (2013) A. J. P. Brown et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Iron restriction-induced adaptations in the wall proteome of Candida albicans
- (2013) A. G. Sorgo et al. MICROBIOLOGY-SGM
- CandidaInfections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents
- (2013) Claudia Spampinato et al. Biomed Research International
- Transcript profiling reveals rewiring of iron assimilation gene expression inCandida albicansandC. dubliniensis
- (2012) Gary P. Moran FEMS YEAST RESEARCH
- The histone acetyltransferase Hat1 facilitates DNA damage repair and morphogenesis inCandida albicans
- (2012) Michael Tscherner et al. MOLECULAR MICROBIOLOGY
- Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer
- (2012) Kelly Coffey et al. PLoS One
- Hidden Killers: Human Fungal Infections
- (2012) G. D. Brown et al. Science Translational Medicine
- A Histone Deacetylase Adjusts Transcription Kinetics at Coding Sequences during Candida albicans Morphogenesis
- (2012) Denes Hnisz et al. PLoS Genetics
- Functional Genomic Analysis of Candida glabrata-Macrophage Interaction: Role of Chromatin Remodeling in Virulence
- (2012) Maruti Nandan Rai et al. PLoS Pathogens
- Type I Interferons Promote Fatal Immunopathology by Regulating Inflammatory Monocytes and Neutrophils during Candida Infections
- (2012) Olivia Majer et al. PLoS Pathogens
- Fungal pathogens—a sweet and sour treat for toll-like receptors
- (2012) Christelle Bourgeois et al. Frontiers in Cellular and Infection Microbiology
- Chromatin-mediated Candida albicans virulence
- (2011) Jessica Lopes da Rosa et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- The Role of MAPK Signal Transduction Pathways in the Response to Oxidative Stress in the Fungal Pathogen Candida albicans: Implications in Virulence
- (2011) Carmen Herrero de Dios et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Efg1 Controls Caspofungin-Induced Cell Aggregation of Candida albicans through the Adhesin Als1
- (2011) Christa Gregori et al. EUKARYOTIC CELL
- Regulatory Circuitry Governing Fungal Development, Drug Resistance, and Disease
- (2011) R. S. Shapiro et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Regulation of white and opaque cell-type formation in Candida albicans by Rtt109 and Hst3
- (2011) John S. Stevenson et al. MOLECULAR MICROBIOLOGY
- Growth of Candida albicans hyphae
- (2011) Peter E. Sudbery NATURE REVIEWS MICROBIOLOGY
- Candida albicans morphogenesis and host defence: discriminating invasion from colonization
- (2011) Neil A. R. Gow et al. NATURE REVIEWS MICROBIOLOGY
- Role of Bcr1-Activated Genes Hwp1 and Hyr1 in Candida Albicans Oral Mucosal Biofilms and Neutrophil Evasion
- (2011) Prabhat Dwivedi et al. PLoS One
- Targeting chromatin in fungal pathogens as a novel therapeutic strategy: histone modification gets infectious
- (2011) Denes Hnisz et al. Epigenomics
- Genome-wide characterisation of the Gcn5 histone acetyltransferase in budding yeast during stress adaptation reveals evolutionarily conserved and diverged roles
- (2010) Yongtao Xue-Franzén et al. BMC GENOMICS
- Cryptococcus neoformans Histone Acetyltransferase Gcn5 Regulates Fungal Adaptation to the Host
- (2010) Teresa R. O'Meara et al. EUKARYOTIC CELL
- Some biological features of Candida albicans mutants for genes coding fungal proteins containing the CFEM domain
- (2010) Ana Pérez et al. FEMS YEAST RESEARCH
- A Role for Gcn5 in Replication-Coupled Nucleosome Assembly
- (2010) Rebecca J. Burgess et al. MOLECULAR CELL
- Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy
- (2010) Hugo Wurtele et al. NATURE MEDICINE
- Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis
- (2010) J. Lopes da Rosa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Extensive Circuitry for Cell Wall Regulation in Candida albicans
- (2010) Jill R. Blankenship et al. PLoS Pathogens
- The Set3/Hos2 Histone Deacetylase Complex Attenuates cAMP/PKA Signaling to Regulate Morphogenesis and Virulence of Candida albicans
- (2010) Denes Hnisz et al. PLoS Pathogens
- TopHat: discovering splice junctions with RNA-Seq
- (2009) Cole Trapnell et al. BIOINFORMATICS
- Fungi sensing environmental stress
- (2009) R. Alonso-Monge et al. CLINICAL MICROBIOLOGY AND INFECTION
- The Ras/cAMP/PKA signaling pathway and virulence inCandida albicans
- (2009) Deborah A Hogan et al. Future Microbiology
- Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens
- (2009) M. A. Pfaller et al. JOURNAL OF CLINICAL MICROBIOLOGY
- A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate
- (2008) Nico Dunkel et al. EUKARYOTIC CELL
- Live Candida albicans Suppresses Production of Reactive Oxygen Species in Phagocytes
- (2008) M. Wellington et al. INFECTION AND IMMUNITY
- Efg1-mediated Recruitment of NuA4 to Promoters Is Required for Hypha-specific Swi/Snf Binding and Activation in Candida albicans
- (2008) Yang Lu et al. MOLECULAR BIOLOGY OF THE CELL
- Candida albicanscell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance
- (2008) Ingrid E. Frohner et al. MOLECULAR MICROBIOLOGY
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