Regulatory Circuitry Governing Fungal Development, Drug Resistance, and Disease

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

(2010) C. M. Martel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

FKS Mutations and Elevated Echinocandin MIC Values among Candida glabrata Isolates from U.S. Population-Based Surveillance

(2010) A. J. Zimbeck et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Heteroresistance of Cryptococcus gattii to Fluconazole

(2010) A. Varma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Transcriptional Regulation of Chitin Synthases by Calcineurin Controls Paradoxical Growth of Aspergillus fumigatus in Response to Caspofungin

(2010) J. R. Fortwendel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Environmental Study of Azole-Resistant Aspergillus fumigatus and Other Aspergilli in Austria, Denmark, and Spain

(2010) K. L. Mortensen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole Resistance Profile of Amino Acid Changes in Aspergillus fumigatus CYP51A Based on Protein Homology Modeling

(2010) E. Snelders et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-  Demethylase (CYP51) Isoenzymes A and B

(2010) A. G. S. Warrilow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection

(2010) D. M. MacCallum et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Heptahelical Receptors GprC and GprD of Aspergillus fumigatus Are Essential Regulators of Colony Growth, Hyphal Morphogenesis, and Virulence

(2010) A. Gehrke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Integrative analysis of the heat shock response in Aspergillus fumigatus

(2010) Daniela Albrecht et al.   BMC GENOMICS

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

Epidemiology of Invasive Mycoses in North America

(2010) Michael A. Pfaller et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Hyphal growth in Candida albicans requires the phosphorylation of Sec2 by the Cdc28-Ccn1/Hgc1 kinase

(2010) Amy Bishop et al.   EMBO JOURNAL

TheUPC2Promoter in Candida albicans Contains Twocis-Acting Elements That Bind Directly to Upc2p, Resulting in Transcriptional Autoregulation

(2010) Samantha J. Hoot et al.   EUKARYOTIC CELL

Candida albicans Ume6, a Filament-Specific Transcriptional Regulator, Directs Hyphal Growth via a Pathway Involving Hgc1 Cyclin-Related Protein

(2010) Patricia L. Carlisle et al.   EUKARYOTIC CELL

Heterologous Expression of Candida albicans Cell Wall-Associated Adhesins in Saccharomyces cerevisiae Reveals Differential Specificities in Adherence and Biofilm Formation and in Binding Oral Streptococcus gordonii

(2010) Angela H. Nobbs et al.   EUKARYOTIC CELL

Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans

(2010) Shinae Maeng et al.   EUKARYOTIC CELL

Spitzenkörper, Exocyst, and Polarisome Components in Candida albicans Hyphae Show Different Patterns of Localization and Have Distinct Dynamic Properties

(2010) Laura A. Jones et al.   EUKARYOTIC CELL

Cryptococcal Interactions with the Host Immune System

(2010) Kerstin Voelz et al.   EUKARYOTIC CELL

Pseudohyphal Regulation by the Transcription Factor Rfg1p in Candida albicans

(2010) Ian A. Cleary et al.   EUKARYOTIC CELL

Role of Transcription Factor CaNdt80p in Cell Separation, Hyphal Growth, and Virulence in Candida albicans

(2010) Adnane Sellam et al.   EUKARYOTIC CELL

The Transcriptional Regulator Nrg1p Controls Candida albicans Biofilm Formation and Dispersion

(2010) Priya Uppuluri et al.   EUKARYOTIC CELL

Candida albicans Pde1p and Gpa2p comprise a regulatory module mediating agonist-induced cAMP signalling and environmental adaptation

(2010) Duncan Wilson et al.   FUNGAL GENETICS AND BIOLOGY

Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway

(2010) Kwang-Woo Jung et al.   FUNGAL GENETICS AND BIOLOGY

Mechanisms of cryptococcal virulence and persistence

(2010) Michal A Olszewski et al.   Future Microbiology

Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus

(2010) W. Fang et al.   GLYCOBIOLOGY

Cryptococcus neoformans Variants Generated by Phenotypic Switching Differ in Virulence through Effects on Macrophage Activation

(2010) A. Guerrero et al.   INFECTION AND IMMUNITY

AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus fumigatus

(2010) Franziska Dirr et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

In Vitro Susceptibility of the Yeast Pathogen Cryptococcus to Fluconazole and Other Azoles Varies with Molecular Genotype

(2010) H. S. Chong et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Nosema ceranae, a new parasite in Thai honeybees

(2010) Guntima Suwannapong et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

The effects of antifungal agents to conidial and hyphal forms ofAspergillus fumigatus

(2010) Wendy W. J. van de Sande et al.   MEDICAL MYCOLOGY

The RGS protein Crg2 is required for establishment and progression of murine pulmonary cryptococcosis

(2010) Amy Whittington et al.   MEDICAL MYCOLOGY

PHR1, a pH-regulated gene of Candida albicans encoding a glucan-remodelling enzyme, is required for adhesion and invasion

(2010) J. Calderon et al.   MICROBIOLOGY-SGM

Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability

(2010) Isabelle Mouyna et al.   MOLECULAR MICROBIOLOGY

The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growth

(2010) Hannah Hope et al.   MOLECULAR MICROBIOLOGY

Divergent Protein Kinase A isoforms co-ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus

(2010) Kevin K. Fuller et al.   MOLECULAR MICROBIOLOGY

Truncated Afyap1 Attenuates Antifungal Susceptibility of Aspergillus fumigatus to Voriconazole and Confers Adaptation of the Fungus to Oxidative Stress

(2010) Jianjun Qiao et al.   MYCOPATHOLOGIA

Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

(2010) Suzanne M Noble et al.   NATURE GENETICS

Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy

(2010) Hugo Wurtele et al.   NATURE MEDICINE

An insight into the antifungal pipeline: selected new molecules and beyond

(2010) Luis Ostrosky-Zeichner et al.   NATURE REVIEWS DRUG DISCOVERY

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Candida albicans AGE3, the Ortholog of the S. cerevisiae ARF-GAP-Encoding Gene GCS1, Is Required for Hyphal Growth and Drug Resistance

(2010) Thomas Lettner et al.   PLoS One

Iridovirus and Microsporidian Linked to Honey Bee Colony Decline

(2010) Jerry J. Bromenshenk et al.   PLoS One

Histone acetyltransferase Rtt109 is required for Candida albicans pathogenesis

(2010) J. Lopes da Rosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin

(2010) Sandra Bruns et al.   PROTEOMICS

Transcription Factors Mat2 and Znf2 Operate Cellular Circuits Orchestrating Opposite- and Same-Sex Mating in Cryptococcus neoformans

(2010) Xiaorong Lin et al.   PLoS Genetics

The Transcriptomes of Two Heritable Cell Types Illuminate the Circuit Governing Their Differentiation

(2010) Brian B. Tuch et al.   PLoS Genetics

The Human Fungal Pathogen Cryptococcus neoformans Escapes Macrophages by a Phagosome Emptying Mechanism That Is Inhibited by Arp2/3 Complex-Mediated Actin Polymerisation

(2010) Simon A. Johnston et al.   PLoS Pathogens

Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

(2010) Sixto M. Leal et al.   PLoS Pathogens

Azole Drugs Are Imported By Facilitated Diffusion in Candida albicans and Other Pathogenic Fungi

(2010) Bryce E. Mansfield et al.   PLoS Pathogens

The Set3/Hos2 Histone Deacetylase Complex Attenuates cAMP/PKA Signaling to Regulate Morphogenesis and Virulence of Candida albicans

(2010) Denes Hnisz et al.   PLoS Pathogens

Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA

(2010) Sandra Bruns et al.   PLoS Pathogens

Requirement for Ergosterol in V-ATPase Function Underlies Antifungal Activity of Azole Drugs

(2010) Yong-Qiang Zhang et al.   PLoS Pathogens

Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle

(2010) Priya Uppuluri et al.   PLoS Pathogens

PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90

(2010) Shantelle L. LaFayette et al.   PLoS Pathogens

Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

(2010) Teresa R. O'Meara et al.   PLoS Pathogens

Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

(2010) Elias Epp et al.   PLoS Pathogens

Cryptococcus neoformans Overcomes Stress of Azole Drugs by Formation of Disomy in Specific Multiple Chromosomes

(2010) Edward Sionov et al.   PLoS Pathogens

Emergence and Pathogenicity of Highly Virulent Cryptococcus gattii Genotypes in the Northwest United States

(2010) Edmond J. Byrnes et al.   PLoS Pathogens

Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity

(2010) Laura H. Okagaki et al.   PLoS Pathogens

Fungal Cell Gigantism during Mammalian Infection

(2010) Oscar Zaragoza et al.   PLoS Pathogens

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Three-Dimensional Model of Lanosterol 14 -Demethylase from Cryptococcus neoformans: Active-Site Characterization and Insights into Azole Binding

(2009) C. Sheng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An A643T Mutation in the Transcription Factor Upc2p Causes Constitutive ERG11 Upregulation and Increased Fluconazole Resistance in Candida albicans

(2009) C. J. Heilmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity Profile In Vitro of Micafungin against Spanish Clinical Isolates of Common and Emerging Species of Yeasts and Molds

(2009) M. Cuenca-Estrella et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Heteroresistance to Fluconazole in Cryptococcus neoformans Is Intrinsic and Associated with Virulence

(2009) E. Sionov et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Possible Environmental Origin of Resistance of Aspergillus fumigatus to Medical Triazoles

(2009) E. Snelders et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model

(2009) Jin Hwan Do et al.   BMC GENOMICS

Interactions ofCandida albicanswith epithelial cells

(2009) Weidong Zhu et al.   CELLULAR MICROBIOLOGY

In vivobiofilm composition ofAspergillus fumigatus

(2009) Céline Loussert et al.   CELLULAR MICROBIOLOGY

Aspergillus fumigatusMedA governs adherence, host cell interactions and virulence

(2009) Fabrice N. Gravelat et al.   CELLULAR MICROBIOLOGY

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

(2009) T. R. T. Dagenais et al.   CLINICAL MICROBIOLOGY REVIEWS

Efflux-Mediated Antifungal Drug Resistance

(2009) R. D. Cannon et al.   CLINICAL MICROBIOLOGY REVIEWS

Our Current Understanding of Fungal Biofilms

(2009) Gordon Ramage et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Hsp90 Orchestrates Temperature-Dependent Candida albicans Morphogenesis via Ras1-PKA Signaling

(2009) Rebecca S. Shapiro et al.   CURRENT BIOLOGY

White–opaque switching in Candida albicans

(2009) Matthew B Lohse et al.   CURRENT OPINION IN MICROBIOLOGY

A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans

(2009) Yen-Ping Hsueh et al.   EMBO JOURNAL

Role of Ndt80p in Sterol Metabolism Regulation and Azole Resistance inCandida albicans

(2009) Adnane Sellam et al.   EUKARYOTIC CELL

Remodeling of Global Transcription Patterns ofCryptococcus neoformansGenes Mediated by the Stress-Activated HOG Signaling Pathways

(2009) Young-Joon Ko et al.   EUKARYOTIC CELL

A Putative P-Type ATPase, Apt1, Is Involved in Stress Tolerance and Virulence inCryptococcus neoformans

(2009) Guanggan Hu et al.   EUKARYOTIC CELL

Aspergillus fumigatusCalcipressin CbpA Is Involved in Hyphal Growth and Calcium Homeostasis

(2009) Nadthanan Pinchai et al.   EUKARYOTIC CELL

Mss11, a Transcriptional Activator, Is Required for Hyphal Development inCandida albicans

(2009) Chang Su et al.   EUKARYOTIC CELL

Deletion of the Protein Kinase A Regulatory Subunit Leads to Deregulation of Mitochondrial Activation and Nuclear Duplication inAspergillus fumigatus

(2009) Kevin K. Fuller et al.   EUKARYOTIC CELL

Conservation of the Sterol Regulatory Element-Binding Protein Pathway and Its Pathobiological Importance inCryptococcus neoformans

(2009) Yun C. Chang et al.   EUKARYOTIC CELL

Msb2 Signaling Mucin Controls Activation of Cek1 Mitogen-Activated Protein Kinase inCandida albicans

(2009) Elvira Román et al.   EUKARYOTIC CELL

Our Paths Might Cross: the Role of the Fungal Cell Wall Integrity Pathway in Stress Response and Cross Talk with Other Stress Response Pathways

(2009) Beth Burgwyn Fuchs et al.   EUKARYOTIC CELL

Comparative Transcript Profiling of Candida albicans and Candida dubliniensis IdentifiesSFL2, a C. albicans Gene Required for Virulence in a Reconstituted Epithelial Infection Model

(2009) Martin J. Spiering et al.   EUKARYOTIC CELL

Streptococcus mutansCompetence-Stimulating Peptide InhibitsCandida albicansHypha Formation

(2009) Lucja M. Jarosz et al.   EUKARYOTIC CELL

Depletion of the Cullin Cdc53p Induces Morphogenetic Changes inCandida albicans

(2009) Katharina Trunk et al.   EUKARYOTIC CELL

The Cek1 MAPK is a short-lived protein regulated by quorum sensing in the fungal pathogenCandida albicans

(2009) Elvira Román et al.   FEMS YEAST RESEARCH

HdaA, a class 2 histone deacetylase of Aspergillus fumigatus, affects germination and secondary metabolite production

(2009) Inhyung Lee et al.   FUNGAL GENETICS AND BIOLOGY

Metabolic control of antifungal drug resistance

(2009) Nicole Robbins et al.   FUNGAL GENETICS AND BIOLOGY

Regulation of multidrug resistance in pathogenic fungi

(2009) Joachim Morschhäuser   FUNGAL GENETICS AND BIOLOGY

Streptococcus gordonii Modulates Candida albicans Biofilm Formation through Intergeneric Communication

(2009) C. V. Bamford et al.   INFECTION AND IMMUNITY

Spores as Infectious Propagules of Cryptococcus neoformans

(2009) R. Velagapudi et al.   INFECTION AND IMMUNITY

Activity of aminocandin (IP960; HMR3270) compared with amphotericin B, itraconazole, caspofungin and micafungin in neutropenic murine models of disseminated infection caused by itraconazole-susceptible and -resistant strains of Aspergillus fumigatus

(2009) Peter A. Warn et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

SAGA and Rpd3 Chromatin Modification Complexes Dynamically Regulate Heat Shock Gene Structure and Expression

(2009) Selena B. Kremer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens

(2009) M. A. Pfaller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Essential Role for Neutrophils but not Alveolar Macrophages at Early Time Points followingAspergillus fumigatusInfection

(2009) Monica M. Mircescu et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular Evidence That the Range of the Vancouver Island Outbreak ofCryptococcus gattiiInfection Has Expanded into the Pacific Northwest in the United States

(2009) Edmond J. Byrnes III et al.   JOURNAL OF INFECTIOUS DISEASES

Apoptosis in Candida biofilms exposed to amphotericin B

(2009) R. S. Al-Dhaheri et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?

(2009) Paul E Verweij et al.   LANCET INFECTIOUS DISEASES

The innate immune response to Aspergillus fumigatus

(2009) Viviane Balloy et al.   MICROBES AND INFECTION

Characterization of the Aspergillus fumigatus phosphomannose isomerase Pmi1 and its impact on cell wall synthesis and morphogenesis

(2009) W. Fang et al.   MICROBIOLOGY-SGM

Hyphal content determines the compression strength of Candida albicans biofilms

(2009) E. Paramonova et al.   MICROBIOLOGY-SGM

Hyphal Chain Formation in Candida albicans: Cdc28-Hgc1 Phosphorylation of Efg1 Represses Cell Separation Genes

(2009) A. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide Mapping of the Coactivator Ada2p Yields Insight into the Functional Roles of SAGA/ADA Complex in Candida albicans

(2009) Adnane Sellam et al.   MOLECULAR BIOLOGY OF THE CELL

Stress-Induced Phenotypic Switching in Candida albicans

(2009) Kevin Alby et al.   MOLECULAR BIOLOGY OF THE CELL

Dissection of the Candida albicans class I chitin synthase promoters

(2009) Megan D. Lenardon et al.   MOLECULAR GENETICS AND GENOMICS

Candida albicansCyr1, Cap1 and G-actin form a sensor/effector apparatus for activating cAMP synthesis in hyphal growth

(2009) Hao Zou et al.   MOLECULAR MICROBIOLOGY

Cryptococcus neoformansSite-2 protease is required for virulence and survival in the presence of azole drugs

(2009) Clara M. Bien et al.   MOLECULAR MICROBIOLOGY

Ras1 and Ras2 play antagonistic roles in regulating cellular cAMP level, stationary-phase entry and stress response inCandida albicans

(2009) Yong Zhu et al.   MOLECULAR MICROBIOLOGY

The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence

(2009) Daniele E. Ejzykowicz et al.   MOLECULAR MICROBIOLOGY

Homothallic and heterothallic mating in the opportunistic pathogen Candida albicans

(2009) Kevin Alby et al.   NATURE

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

(2009) Geraldine Butler et al.   NATURE

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

(2009) Leah E. Cowen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

(2009) Anna M. Selmecki et al.   PLoS Genetics

A Phenotypic Profile of the Candida albicans Regulatory Network

(2009) Oliver R. Homann et al.   PLoS Genetics

A Role for the Unfolded Protein Response (UPR) in Virulence and Antifungal Susceptibility in Aspergillus fumigatus

(2009) Daryl L. Richie et al.   PLoS Pathogens

Rapid Global Expansion of the Fungal Disease Chytridiomycosis into Declining and Healthy Amphibian Populations

(2009) Timothy Y. James et al.   PLoS Pathogens

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

(2009) Sheena D. Singh et al.   PLoS Pathogens

The Protein Kinase Tor1 Regulates Adhesin Gene Expression in Candida albicans

(2009) Robert J. Bastidas et al.   PLoS Pathogens

The histone deacetylase Rpd3p is required for transient changes in genomic expression in response to stress

(2009) Adriana L Alejandro-Osorio et al.   GENOME BIOLOGY

Mutations in the fks1 Gene in Candida albicans, C. tropicalis, and C. krusei Correlate with Elevated Caspofungin MICs Uncovered in AM3 Medium Using the Method of the European Committee on Antibiotic Susceptibility Testing

(2008) M. Desnos-Ollivier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergistic Effect of Calcineurin Inhibitors and Fluconazole against Candida albicans Biofilms

(2008) P. Uppuluri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Differential Effects of Inhibiting Chitin and 1,3- -D-Glucan Synthesis in Ras and Calcineurin Mutants of Aspergillus fumigatus

(2008) J. R. Fortwendel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Aspergillus fumigatus Forms Biofilms with Reduced Antifungal Drug Susceptibility on Bronchial Epithelial Cells

(2008) M. J. Seidler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potential Basis for Amphotericin B Resistance in Aspergillus terreus

(2008) G. Blum et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans

(2008) Oliver W. Liu et al.   CELL

Bacterial Peptidoglycan Triggers Candida albicans Hyphal Growth by Directly Activating the Adenylyl Cyclase Cyr1p

(2008) Xiao-Li Xu et al.   Cell Host & Microbe

Candida albicanstranscription factor Rim101 mediates pathogenic interactions through cell wall functions

(2008) Clarissa J. Nobile et al.   CELLULAR MICROBIOLOGY

Aspergillus fumigatus: virulence genes in a street-smart mold

(2008) David S Askew   CURRENT OPINION IN MICROBIOLOGY

Subcellular Localization Directs Signaling Specificity of theCryptococcus neoformansRas1 Protein

(2008) Connie B. Nichols et al.   EUKARYOTIC CELL

Impaired Ribosome Biogenesis Disrupts the Integration between Morphogenesis and Nuclear Duplication during the Germination ofAspergillus fumigatus

(2008) Ruchi Bhabhra et al.   EUKARYOTIC CELL

The RGS Protein Crg2 Regulates Pheromone and Cyclic AMP Signaling inCryptococcus neoformans

(2008) Gui Shen et al.   EUKARYOTIC CELL

Mutational Analysis of theCandida albicansAmmonium Permease Mep2p Reveals Residues Required for Ammonium Transport and Signaling

(2008) Neelam Dabas et al.   EUKARYOTIC CELL

Master and Commander in Fungal Pathogens: the Two-Component System and the HOG Signaling Pathway

(2008) Yong-Sun Bahn   EUKARYOTIC CELL

Calcineurin Localizes to the Hyphal Septum inAspergillus fumigatus: Implications for Septum Formation and Conidiophore Development

(2008) Praveen Rao Juvvadi et al.   EUKARYOTIC CELL

Transcriptional Profiling Identifies a Role for BrlA in the Response to Nitrogen Depletion and for StuA in the Regulation of Secondary Metabolite Clusters inAspergillus fumigatus

(2008) Kwame Twumasi-Boateng et al.   EUKARYOTIC CELL

Calcineurin Target CrzA Regulates Conidial Germination, Hyphal Growth, and Pathogenesis ofAspergillus fumigatus

(2008) Robert A. Cramer et al.   EUKARYOTIC CELL

Aspergillus fumigatusRasA Regulates Asexual Development and Cell Wall Integrity

(2008) Jarrod R. Fortwendel et al.   EUKARYOTIC CELL

Stress, Drugs, and Evolution: the Role of Cellular Signaling in Fungal Drug Resistance

(2008) Leah E. Cowen et al.   EUKARYOTIC CELL

PKC1Is Essential for Protection against both Oxidative and Nitrosative Stresses, Cell Integrity, and Normal Manifestation of Virulence Factors in the Pathogenic FungusCryptococcus neoformans

(2008) Kimberly J. Gerik et al.   EUKARYOTIC CELL

A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate

(2008) Nico Dunkel et al.   EUKARYOTIC CELL

Candida albicansTup1 Is Involved in Farnesol-Mediated Inhibition of Filamentous-Growth Induction

(2008) Bessie W. Kebaara et al.   EUKARYOTIC CELL

Afcwh41is required for cell wall synthesis, conidiation, and polarity inAspergillus fumigatus

(2008) Lei Zhang et al.   FEMS MICROBIOLOGY LETTERS

The ABC transporter-encoding geneAFR1affects the resistance ofCryptococcus neoformansto microglia-mediated antifungal activity by delaying phagosomal maturation

(2008) Carlotta Francesca Orsi et al.   FEMS YEAST RESEARCH

A small G protein Rhb1 and a GTPase-activating protein Tsc2 involved in nitrogen starvation-induced morphogenesis and cell wall integrity of Candida albicans

(2008) Chang-Chih Tsao et al.   FUNGAL GENETICS AND BIOLOGY

The Sho1 Sensor Regulates Growth, Morphology, and Oxidant Adaptation in Aspergillus fumigatus but Is Not Essential for Development of Invasive Pulmonary Aspergillosis

(2008) Y. Ma et al.   INFECTION AND IMMUNITY

Combined Inactivation of the Candida albicans GPR1 and TPS2 Genes Results in Avirulence in a Mouse Model for Systemic Infection

(2008) M. M. Maidan et al.   INFECTION AND IMMUNITY

Amphotericin B lipid complex is efficacious in the treatment of Candida albicans biofilms using a model of catheter-associated Candida biofilms

(2008) Pranab K. Mukherjee et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: 10.5-Year Analysis of Susceptibilities of Noncandidal Yeast Species to Fluconazole and Voriconazole Determined by CLSI Standardized Disk Diffusion Testing

(2008) M. A. Pfaller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The characteristics ofAspergillus fumigatusmycetoma development: is this a biofilm?

(2008) Eilidh Mowat et al.   MEDICAL MYCOLOGY

Transcript profiling of a MAP kinase pathway in C. albicans

(2008) Hao Huang et al.   MICROBIOLOGICAL RESEARCH

GDP-mannose pyrophosphorylase is essential for cell wall integrity, morphogenesis and viability of Aspergillus fumigatus

(2008) H. Jiang et al.   MICROBIOLOGY-SGM

Deletion of the msdS/AfmsdC gene induces abnormal polarity and septation in Aspergillus fumigatus

(2008) Y. Li et al.   MICROBIOLOGY-SGM

Sep7 Is Essential to Modify Septin Ring Dynamics and Inhibit Cell Separation during Candida albicans Hyphal Growth

(2008) Alberto González-Novo et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of Rac1 by the Guanine Nucleotide Exchange Factor Dck1 Is Required for Invasive Filamentous Growth in the Pathogen Candida albicans

(2008) Hannah Hope et al.   MOLECULAR BIOLOGY OF THE CELL

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA

(2008) Frederico Marianetti Soriani et al.   MOLECULAR MICROBIOLOGY

Mutations in the multi-drug resistance regulatorMRR1, followed by loss of heterozygosity, are the main cause ofMDR1overexpression in fluconazole-resistantCandida albicansstrains

(2008) Nico Dunkel et al.   MOLECULAR MICROBIOLOGY

An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1

(2008) Anna Selmecki et al.   MOLECULAR MICROBIOLOGY

The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype

(2008) Leah E. Cowen   NATURE REVIEWS MICROBIOLOGY

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

(2008) Xiang-Jiao Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genes Differentially Expressed in Conidia and Hyphae of Aspergillus fumigatus upon Exposure to Human Neutrophils

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Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence

(2008) P. L. Carlisle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation

(2008) J. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micafungin alone or in combination with other systemic antifungal therapies in hematopoietic stem cell transplant recipients with invasive aspergillosis

(2008) D.P. Kontoyiannis et al.   Transplant Infectious Disease

Role of Sho1p adaptor in the pseudohyphal development, drugs sensitivity, osmotolerance and oxidant stress adaptation in the opportunistic yeastCandida lusitaniae

(2008) Stéphanie Boisnard et al.   YEAST

The Parasexual Cycle in Candida albicans Provides an Alternative Pathway to Meiosis for the Formation of Recombinant Strains

(2008) Anja Forche et al.   PLOS BIOLOGY

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

(2008) Robert T. Wheeler et al.   PLoS Pathogens

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

(2008) Sven D. Willger et al.   PLoS Pathogens

Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

(2008) Louise A. Walker et al.   PLoS Pathogens

The emergence of Cryptococcus gattii in British Columbia and the Pacific Northwest

(2008) Karen H. Bartlett et al.   Current Infectious Disease Reports

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response

(2007) Vito Valiante et al.   FUNGAL GENETICS AND BIOLOGY

Caspofungin-resistant Aspergillus flavus after heart transplantation and mechanical circulatory support: a case report

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Ras links cellular morphogenesis to virulence by regulation of the MAP kinase and cAMP signalling pathways in the pathogenic fungus Candida albicans

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