Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

The interplay between inflammasome activation and antifungal host defense

(2015) Frank L. van de Veerdonk et al.   IMMUNOLOGICAL REVIEWS

Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface

(2015) David L Moyes et al.   Virulence

VulvovaginalCandida albicansinfections: pathogenesis, immunity and vaccine prospects

(2014) A Cassone   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Interplay between Candida albicans and the Antimicrobial Peptide Armory

(2014) Marc Swidergall et al.   EUKARYOTIC CELL

The bacteriome-mycobiome interaction and antifungal host defense

(2014) Jaap ten Oever et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathogenicity mechanisms and host response during oral Candida albicans infections

(2014) Betty Hebecker et al.   Expert Review of Anti-Infective Therapy

Impact of Staphylococcus aureus on Pathogenesis in Polymicrobial Infections

(2014) N. Nair et al.   INFECTION AND IMMUNITY

Fungal invasion of epithelial cells

(2014) Weiming Yang et al.   MICROBIOLOGICAL RESEARCH

Real-Time Microscopic Observation of Candida Biofilm Development and Effects Due to Micafungin and Fluconazole

(2013) Yukihiro Kaneko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Candida albicans Mucin Msb2 Is a Broad-Range Protectant against Antimicrobial Peptides

(2013) Marc Swidergall et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Candida albicans Flu1-Mediated Efflux of Salivary Histatin 5 Reduces Its Cytosolic Concentration and Fungicidal Activity

(2013) Rui Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Unstimulated whole salivary flow rate and anxiolytics intake are independently associated with oralCandidainfection in patients with oral lichen planus

(2013) Marija Bokor-Bratic et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Role for the fibrinogen-binding proteins Coagulase and Efb in the Staphylococcus aureus–Candida interaction

(2013) Carsten Fehrmann et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Protection Against Epithelial Damage During Candida albicans Infection Is Mediated by PI3K/Akt and Mammalian Target of Rapamycin Signaling

(2013) David L. Moyes et al.   JOURNAL OF INFECTIOUS DISEASES

Prevalence of Recurrent Vulvovaginal Candidiasis in 5 European Countries and the United States

(2013) Betsy Foxman et al.   Journal of Lower Genital Tract Disease

Oral candidosis in relation to oral immunity

(2013) L. Feller et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Disruption of the intestinal mucosal barrier in Candida albicans infections

(2013) Lei Yan et al.   MICROBIOLOGICAL RESEARCH

Complement and innate immune evasion strategies of the human pathogenic fungus Candida albicans

(2013) Shanshan Luo et al.   MOLECULAR IMMUNOLOGY

Candida albicanspathogenicity mechanisms

(2013) François L. Mayer et al.   Virulence

A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans

(2012) Clarissa J. Nobile et al.   CELL

Importance of the Candida albicans cell wall during commensalism and infection

(2012) Neil AR Gow et al.   CURRENT OPINION IN MICROBIOLOGY

White-Opaque Switching of Candida albicans Allows Immune Evasion in an Environment-Dependent Fashion

(2012) Christoph Sasse et al.   EUKARYOTIC CELL

Interplay between Candida albicans and the Mammalian Innate Host Defense

(2012) Shih-Chin Cheng et al.   INFECTION AND IMMUNITY

Mouse estrous cycle regulation of vaginal versus uterine cytokines, chemokines, α-/β-defensins and TLRs

(2012) Danica K Hickey et al.   Innate Immunity

Chronic Mucocutaneous Candidiasis Caused by a Gain-of-Function Mutation in the STAT1 DNA-Binding Domain

(2012) S. Takezaki et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-17-Secreting Innate Lymphoid Cells Are Essential for Host Defense against Fungal Infection

(2012) A. Gladiator et al.   JOURNAL OF IMMUNOLOGY

Candida albicans Biofilms Do Not Trigger Reactive Oxygen Species and Evade Neutrophil Killing

(2012) Z. Xie et al.   JOURNAL OF INFECTIOUS DISEASES

Staphylococcus aureus adherence to Candida albicans hyphae is mediated by the hyphal adhesin Als3p

(2012) Brian M. Peters et al.   MICROBIOLOGY-SGM

Induction of apoptosis in oral epithelial cells byCandida albicans

(2012) C. Cunha Villar et al.   Molecular Oral Microbiology

Candida albicans-Epithelial Interactions: Dissecting the Roles of Active Penetration, Induced Endocytosis and Host Factors on the Infection Process

(2012) Betty Wächtler et al.   PLoS One

Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis

(2012) Sumant Puri et al.   PLoS One

Glycosylation of Candida albicans Cell Wall Proteins Is Critical for Induction of Innate Immune Responses and Apoptosis of Epithelial Cells

(2012) Jeanette Wagener et al.   PLoS One

Dissociable neural representations of reinforcement and belief prediction errors underlie strategic learning

(2012) L. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Novel Candida albicans Transporter Dur31 Is a Multi-Stage Pathogenicity Factor

(2012) François L. Mayer et al.   PLoS Pathogens

Msb2 Shedding Protects Candida albicans against Antimicrobial Peptides

(2012) Eva Szafranski-Schneider et al.   PLoS Pathogens

Fungal Biofilms

(2012) Saranna Fanning et al.   PLoS Pathogens

A Candida Biofilm-Induced Pathway for Matrix Glucan Delivery: Implications for Drug Resistance

(2012) Heather T. Taff et al.   PLoS Pathogens

Superoxide Dismutases Are Involved in Candida albicans Biofilm Persistence against Miconazole

(2011) Anna Bink et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

LL37 and hBD-3 elevate the β-1,3-exoglucanase activity ofCandida albicansXog1p, resulting in reduced fungal adhesion to plastic

(2011) Hao-Teng Chang et al.   BIOCHEMICAL JOURNAL

Candida albicansdimorphism as a therapeutic target

(2011) Ilse D Jacobsen et al.   Expert Review of Anti-Infective Therapy

Adaptation, adhesion and invasion during interaction of Candida albicans with the host – Focus on the function of cell wall proteins

(2011) Ekkehard Hiller et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Interaction of the mucosal barrier with accessory immune cells during fungal infection

(2011) Günther Weindl et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Immune escape of the human facultative pathogenic yeast Candida albicans: The many faces of the Candida Pra1 protein

(2011) Peter F. Zipfel et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The pH-regulated Antigen 1 ofCandida albicansBinds the Human Complement Inhibitor C4b-binding Protein and Mediates Fungal Complement Evasion

(2011) Shanshan Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic Variation in the Dectin-1/CARD9 Recognition Pathway and Susceptibility to Candidemia

(2011) Diana C. Rosentul et al.   JOURNAL OF INFECTIOUS DISEASES

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

(2011) Shih-Chin Cheng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate and adaptive immunity at mucosal surfaces of the female reproductive tract: stratification and integration of immune protection against the transmission of sexually transmitted infections

(2011) D.K. Hickey et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Emerging opportunistic yeast infections

(2011) Marisa H Miceli et al.   LANCET INFECTIOUS DISEASES

Activation of MAPK/c-Fos induced responses in oral epithelial cells is specific to Candida albicans and Candida dubliniensis hyphae

(2011) David L. Moyes et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Candida albicans interactions with epithelial cells and mucosal immunity

(2011) Julian R. Naglik et al.   MICROBES AND INFECTION

Immunomodulatory and protective effect of probiotic Lactobacillus casei against Candida albicans infection in malnourished mice

(2011) Julio Villena et al.   MICROBIOLOGY AND IMMUNOLOGY

Growth of Candida albicans hyphae

(2011) Peter E. Sudbery   NATURE REVIEWS MICROBIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Frank L. van de Veerdonk et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Antimicrobial Peptide LL-37 Inhibits Adhesion of Candida albicans by Interacting with Yeast Cell-Wall Carbohydrates

(2011) Pei-Wen Tsai et al.   PLoS One

From Attachment to Damage: Defined Genes of Candida albicans Mediate Adhesion, Invasion and Damage during Interaction with Oral Epithelial Cells

(2011) Betty Wächtler et al.   PLoS One

STAT1 Hyperphosphorylation and Defective IL12R/IL23R Signaling Underlie Defective Immunity in Autosomal Dominant Chronic Mucocutaneous Candidiasis

(2011) Sanne P. Smeekens et al.   PLoS One

Candida albicans Yeast and Hyphae are Discriminated by MAPK Signaling in Vaginal Epithelial Cells

(2011) David L. Moyes et al.   PLoS One

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

The Fungal Pathogen Candida albicans Autoinduces Hyphal Morphogenesis by Raising Extracellular pH

(2011) S. Vylkova et al.   mBio

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Role of Fks1p and Matrix Glucan in Candida albicans Biofilm Resistance to an Echinocandin, Pyrimidine, and Polyene

(2010) J. E. Nett et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

Epidemiology of Invasive Mycoses in North America

(2010) Michael A. Pfaller et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Pathogenesis of invasive candidiasis

(2010) Frank L van de Veerdonk et al.   Current Opinion in Critical Care

Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape

(2010) Katja Seider et al.   CURRENT OPINION IN MICROBIOLOGY

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease

(2010) Reiko M. Onishi et al.   IMMUNOLOGY

Epithelial Cell-Derived S100 Calcium-Binding Proteins as Key Mediators in the Hallmark Acute Neutrophil Response during Candida Vaginitis

(2010) J. Yano et al.   INFECTION AND IMMUNITY

Contribution of Candida albicans Cell Wall Components to Recognition by and Escape from Murine Macrophages

(2010) C. G. J. McKenzie et al.   INFECTION AND IMMUNITY

Severe Candida spp. infections: new insights into natural immunity

(2010) Jos W.M. van der Meer et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Epithelial Cells and Innate Antifungal Defense

(2010) G. Weindl et al.   JOURNAL OF DENTAL RESEARCH

The expression of β-defensin-2, 3 and LL-37 induced by Candida albicans phospholipomannan in human keratinocytes

(2010) Min Li et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Secreted pH-Regulated Antigen 1 of Candida albicans Blocks Activation and Conversion of Complement C3

(2010) S. Luo et al.   JOURNAL OF IMMUNOLOGY

Candida albicans Dampens Host Defense by Downregulating IL-17 Production

(2010) S.-C. Cheng et al.   JOURNAL OF IMMUNOLOGY

Host responses to Candida albicans: Th17 cells and mucosal candidiasis

(2010) Heather R. Conti et al.   MICROBES AND INFECTION

Antifungal mechanisms by which a novel Pseudomonas aeruginosa phenazine toxin kills Candida albicans in biofilms

(2010) Diana K. Morales et al.   MOLECULAR MICROBIOLOGY

Candida albicans induces early apoptosis followed by secondary necrosis in oral epithelial cells

(2010) C.C. Villar et al.   Molecular Oral Microbiology

IL-22 defines a novel immune pathway of antifungal resistance

(2010) A De Luca et al.   Mucosal Immunology

Innate immune mechanisms for recognition and uptake of Candida species

(2010) Mihai G. Netea et al.   TRENDS IN IMMUNOLOGY

Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle

(2010) Priya Uppuluri et al.   PLoS Pathogens

Host Cell Invasion and Virulence Mediated by Candida albicans Ssa1

(2010) Jianing N. Sun et al.   PLoS Pathogens

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Candida albicans and Staphylococcus aureus Form Polymicrobial Biofilms: Effects on Antimicrobial Resistance

(2009) M. M. Harriott et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The role of salivary factors in persistent oral carriage of Candida in humans

(2009) Kyoko Hibino et al.   ARCHIVES OF ORAL BIOLOGY

Candida albicansactively modulates intracellular membrane trafficking in mouse macrophage phagosomes

(2009) Elena Fernández-Arenas et al.   CELLULAR MICROBIOLOGY

Candida albicansinternalization by host cells is mediated by a clathrin-dependent mechanism

(2009) Emilia Moreno-Ruiz et al.   CELLULAR MICROBIOLOGY

Stimulation of cell motility and expression of late markers of differentiation in human oral keratinocytes byCandida albicans

(2009) Christiane Rollenhagen et al.   CELLULAR MICROBIOLOGY

Interactions ofCandida albicanswith epithelial cells

(2009) Weidong Zhu et al.   CELLULAR MICROBIOLOGY

Cellular interactions ofCandida albicanswith human oral epithelial cells and enterocytes

(2009) Frederic Dalle et al.   CELLULAR MICROBIOLOGY

Our Current Understanding of Fungal Biofilms

(2009) Gordon Ramage et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

(2009) Paul Williams et al.   CURRENT OPINION IN MICROBIOLOGY

Cross-kingdom interactions:Candida albicansand bacteria

(2009) Mark E. Shirtliff et al.   FEMS MICROBIOLOGY LETTERS

Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2

(2009) S T. Hollmig et al.   GLYCOBIOLOGY

Arginine-Induced Germ Tube Formation in Candida albicans Is Essential for Escape from Murine Macrophage Line RAW 264.7

(2009) S. Ghosh et al.   INFECTION AND IMMUNITY

Streptococcus gordonii Modulates Candida albicans Biofilm Formation through Intergeneric Communication

(2009) C. V. Bamford et al.   INFECTION AND IMMUNITY

Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome

(2009) S. Joly et al.   JOURNAL OF IMMUNOLOGY

Time Course Global Gene Expression Analysis of an In VivoCandidaBiofilm

(2009) Jeniel E. Nett et al.   JOURNAL OF INFECTIOUS DISEASES

Immune evasion of the human pathogenic yeast Candida albicans: Pra1 is a Factor H, FHL-1 and plasminogen binding surface protein

(2009) Shanshan Luo et al.   MOLECULAR IMMUNOLOGY

The yeast Candida albicans evades human complement attack by secretion of aspartic proteases

(2009) Katharina Gropp et al.   MOLECULAR IMMUNOLOGY

Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa

(2009) S A Khader et al.   Mucosal Immunology

A Novel Immune Evasion Strategy of Candida albicans: Proteolytic Cleavage of a Salivary Antimicrobial Peptide

(2009) Timothy F. Meiller et al.   PLoS One

Effects of the cathelicidin LL-37 on intestinal epithelial barrier integrity

(2009) Jan-Michel Otte et al.   REGULATORY PEPTIDES

NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens

(2009) Igor E. Brodsky et al.   SEMINARS IN IMMUNOLOGY

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Antifungal Activities of Human Beta-Defensins HBD-1 to HBD-3 and Their C-Terminal Analogs Phd1 to Phd3

(2008) V. Krishnakumari et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pseudomonas aeruginosa-Candida albicans Interactions: Localization and Fungal Toxicity of a Phenazine Derivative

(2008) J. Gibson et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Complementary Adhesin Function in C. albicans Biofilm Formation

(2008) Clarissa J. Nobile et al.   CURRENT BIOLOGY

Candida albicansTup1 Is Involved in Farnesol-Mediated Inhibition of Filamentous-Growth Induction

(2008) Bessie W. Kebaara et al.   EUKARYOTIC CELL

Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients: Part I. Epidemiology and diagnosis

(2008) Benoît P. Guery et al.   INTENSIVE CARE MEDICINE

Dendritic Cell Interaction withCandida albicansCritically Depends onN-Linked Mannan

(2008) Alessandra Cambi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogen recognition by innate receptors

(2008) Yutaro Kumagai et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

The interaction of mannose binding lectin (MBL) with mannose containing glycopeptides and the resultant potential impact on invasive fungal infection

(2008) Patricia I. Sealy et al.   MEDICAL MYCOLOGY

Candida albicans Cell Wall Proteins

(2008) W. L. Chaffin   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Secreted proteinases and Candida albicans virulence

(2008) F. C. Odds   MICROBIOLOGY-SGM

Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis

(2008) Julian R. Naglik et al.   MICROBIOLOGY-SGM

Distinct domains of the Candida albicans adhesin Eap1p mediate cell–cell and cell–substrate interactions

(2008) Fang Li et al.   MICROBIOLOGY-SGM

Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans

(2008) Ulrich Lermann et al.   MICROBIOLOGY-SGM

Uptake of the antifungal cationic peptide Histatin 5 byCandida albicansSsa2p requires binding to non-conventional sites within the ATPase domain

(2008) Jianing N. Sun et al.   MOLECULAR MICROBIOLOGY

Candida albicanscell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance

(2008) Ingrid E. Frohner et al.   MOLECULAR MICROBIOLOGY

Novel Insights into Disseminated Candidiasis: Pathogenesis Research and Clinical Experience Converge

(2008) Brad Spellberg   PLoS Pathogens

Prokaryote-eukaryote interactions identified by using Caenorhabditis elegans

(2008) A. Y. Peleg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

(2008) Robert T. Wheeler et al.   PLoS Pathogens

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY

C-type lectin receptors in antifungal immunity

(2007) Janet A. Willment et al.   TRENDS IN MICROBIOLOGY