Structural underpinnings of Ric8A function as a G-protein α-subunit chaperone and guanine-nucleotide exchange factor

Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange

(2018) Makaía M. Papasergi-Scott et al.   Science Signaling

Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange

(2018) Makaía M. Papasergi-Scott et al.   Science Signaling

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

(2018) Yanyong Kang et al.   NATURE

GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism

(2018) Hikaru Shimizu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity

(2018) Ching-Ju Tsai et al.   Science Advances

Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

(2017) Yi-Lynn Liang et al.   NATURE

Selectivity determinants of GPCR–G-protein binding

(2017) Tilman Flock et al.   NATURE

Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein

(2017) Yan Zhang et al.   NATURE

Acidic C-terminal domains autoregulate the RNA chaperone Hfq

(2017) Andrew Santiago-Frangos et al.   eLife

BioXTAS RAW: improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis

(2017) Jesse Bennett Hopkins et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

(2017) D. Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Mini-G proteins: Novel tools for studying GPCRs in their active conformation

(2017) Rony Nehmé et al.   PLoS One

Structure of the adenosine A2A receptor bound to an engineered G protein

(2016) Byron Carpenter et al.   NATURE

Dali server update

(2016) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα

(2016) Ravi Kant et al.   eLife

QwikMD — Integrative Molecular Dynamics Toolkit for Novices and Experts

(2016) João V. Ribeiro et al.   Scientific Reports

Universal allosteric mechanism for Gα activation by GPCRs

(2015) Tilman Flock et al.   NATURE

The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1

(2015) Ned Van Eps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for nucleotide exchange in heterotrimeric G proteins

(2015) R. O. Dror et al.   SCIENCE

Rapid Identification and Quantitative Validation of a Caffeine-Degrading Pathway in Pseudomonas sp. CES

(2014) Chi Li Yu et al.   JOURNAL OF PROTEOME RESEARCH

Distance restraints from crosslinking mass spectrometry: Mining a molecular dynamics simulation database to evaluate lysine-lysine distances

(2014) Eric D. Merkley et al.   PROTEIN SCIENCE

Ric-8 regulation of heterotrimeric G proteins

(2013) Gregory G. Tall   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Matching Cross-linked Peptide Spectra: Only as Good as the Worse Identification

(2013) Michael J. Trnka et al.   MOLECULAR & CELLULAR PROTEOMICS

Cross-Link Guided Molecular Modeling with ROSETTA

(2013) Abdullah Kahraman et al.   PLoS One

Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein   subunits

(2013) P. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPU/CPU Algorithm for Generalized Born/Solvent-Accessible Surface Area Implicit Solvent Calculations

(2012) David E. Tanner et al.   Journal of Chemical Theory and Computation

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

RIC8 Is a Guanine-Nucleotide Exchange Factor for Gα Subunits That Regulates Growth and Development inNeurospora crassa

(2011) Sara J. Wright et al.   GENETICS

Parallel Generalized Born Implicit Solvent Calculations with NAMD

(2011) David E. Tanner et al.   Journal of Chemical Theory and Computation

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

The Nucleotide Exchange Factor Ric-8A Is a Chaperone for the Conformationally Dynamic Nucleotide-Free State of Gαi1

(2011) Celestine J. Thomas et al.   PLoS One

An approach to crystallizing proteins by metal-mediated synthetic symmetrization

(2011) Arthur Laganowsky et al.   PROTEIN SCIENCE

Ric-8 Proteins Are Molecular Chaperones That Direct Nascent G Protein   Subunit Membrane Association

(2011) M. Gabay et al.   Science Signaling

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Purification of Heterotrimeric G Protein α Subunits by GST-Ric-8 Association

(2010) PuiYee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ric-8B Stabilizes the α Subunit of Stimulatory G Protein by Inhibiting Its Ubiquitination

(2010) Yusuke Nagai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Armadillo-repeat protein functions: questions for little creatures

(2010) Rita Tewari et al.   TRENDS IN CELL BIOLOGY

Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates

(2009) Gary Kleiger et al.   CELL

Structure and flexibility within proteins as identified through small angle X-ray scattering

(2009) M. Pelikan et al.   GENERAL PHYSIOLOGY AND BIOPHYSICS

Biophysical studies support a predicted superhelical structure with armadillo repeats for Ric-8

(2009) Maximiliano Figueroa et al.   PROTEIN SCIENCE

In-depth Analysis of Tandem Mass Spectrometry Data from Disparate Instrument Types

(2008) Robert J. Chalkley et al.   MOLECULAR & CELLULAR PROTEOMICS

Heterotrimeric G protein activation by G-protein-coupled receptors

(2007) William M. Oldham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY