Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα

Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding

(2016) David Goricanec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Universal allosteric mechanism for Gα activation by GPCRs

(2015) Tilman Flock et al.   NATURE

PeptideShaker enables reanalysis of MS-derived proteomics data sets

(2015) Marc Vaudel et al.   NATURE BIOTECHNOLOGY

JPred4: a protein secondary structure prediction server

(2015) Alexey Drozdetskiy et al.   NUCLEIC ACIDS RESEARCH

The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1

(2015) Ned Van Eps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for nucleotide exchange in heterotrimeric G proteins

(2015) R. O. Dror et al.   SCIENCE

Ubiquitination of the heterotrimeric G protein α subunits Gαi2 and Gαq is prevented by the guanine nucleotide exchange factor Ric-8A

(2013) Kanako Chishiki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ric-8 regulation of heterotrimeric G proteins

(2013) Gregory G. Tall   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein   subunits

(2013) P. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis

(2013) R. Kataria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myristoylation Exerts Direct and Allosteric Effects on Gα Conformation and Dynamics in Solution

(2012) Anita M. Preininger et al.   BIOCHEMISTRY

Regulation of the G-protein Regulatory-GαiSignaling Complex by Nonreceptor Guanine Nucleotide Exchange Factors

(2012) Sukru Sadik Oner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ric-8: Different cellular roles for a heterotrimeric G-protein GEF

(2012) M.V. Hinrichs et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Resistance to Inhibitors of Cholinesterase-8A (Ric-8A) Is Critical for Growth Factor Receptor-induced Actin Cytoskeletal Reorganization

(2011) Limin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SmgGDS Is a Guanine Nucleotide Exchange Factor That Specifically Activates RhoA and RhoC

(2011) Brant Hamel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

(2011) Ka Young Chung et al.   NATURE

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

The Nucleotide Exchange Factor Ric-8A Is a Chaperone for the Conformationally Dynamic Nucleotide-Free State of Gαi1

(2011) Celestine J. Thomas et al.   PLoS One

Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit

(2011) N. Van Eps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural flexibility of the G s  -helical domain in the  2-adrenoceptor Gs complex

(2011) G. H. Westfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ric-8 Proteins Are Molecular Chaperones That Direct Nascent G Protein   Subunit Membrane Association

(2011) M. Gabay et al.   Science Signaling

Nucleotide exchange factor RIC-8 is indispensable in mammalian early development

(2010) Tambet Tõnissoo et al.   DEVELOPMENTAL DYNAMICS

MSTools—Web based application for visualization and presentation of HXMS data

(2010) Daniel Kavan et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Ric-8B Stabilizes the α Subunit of Stimulatory G Protein by Inhibiting Its Ubiquitination

(2010) Yusuke Nagai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ric-8A and Gi  Recruit LGN, NuMA, and Dynein to the Cell Cortex To Help Orient the Mitotic Spindle

(2010) G. E. Woodard et al.   MOLECULAR AND CELLULAR BIOLOGY

Biophysical studies support a predicted superhelical structure with armadillo repeats for Ric-8

(2009) Maximiliano Figueroa et al.   PROTEIN SCIENCE

Ric-8A Catalyzes Guanine Nucleotide Exchange on Gαi1Bound to the GPR/GoLoco Exchange Inhibitor AGS3

(2008) Celestine J. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of opsin in its G-protein-interacting conformation

(2008) Patrick Scheerer et al.   NATURE

Heterotrimeric G protein activation by G-protein-coupled receptors

(2007) William M. Oldham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY