Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation
出版年份 2019 全文链接
标题
Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-06-03
DOI
10.1038/s41467-019-10176-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Myeloid-derived suppressor cells coming of age
- (2018) Filippo Veglia et al. NATURE IMMUNOLOGY
- Chemically induced mouse models of acute and chronic intestinal inflammation
- (2017) Stefan Wirtz et al. Nature Protocols
- Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis
- (2017) Yongfeng Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of Pediatric Inflammatory Bowel Disease
- (2016) Joanna M. Peloquin et al. Annual Review of Immunology
- The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD)
- (2016) Olga F. Sarmento et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10
- (2016) Alfa H. C. Bai et al. Journal of Crohns & Colitis
- The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
- (2016) Vinit Kumar et al. TRENDS IN IMMUNOLOGY
- Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells
- (2016) Jan Däbritz et al. Scientific Reports
- Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι
- (2016) Yuki Nakanishi et al. Cell Reports
- Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
- (2016) Ludovica Morera et al. Clinical Epigenetics
- TNF Neutralization Results in the Delay of Transplantable Tumor Growth and Reduced MDSC Accumulation
- (2016) Kamar-Sulu N. Atretkhany et al. Frontiers in Immunology
- Reprogramming the lung microenvironment by inhaled immunotherapy fosters immune destruction of tumor
- (2016) Valentino Le Noci et al. OncoImmunology
- The Chromatin-Modifying Enzyme Ezh2 Is Critical for the Maintenance of Regulatory T Cell Identity after Activation
- (2015) Michel DuPage et al. IMMUNITY
- Mechanisms of NLRP3 inflammasome activation and its role in NSAID-induced enteropathy
- (2015) A Higashimori et al. Mucosal Immunology
- Immunopathogenesis of IBD: current state of the art
- (2015) Heitor S. P. de Souza et al. Nature Reviews Gastroenterology & Hepatology
- Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity
- (2015) Jie Yin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Review article: selective histone deacetylase isoforms as potential therapeutic targets in inflammatory bowel diseases
- (2014) C. Felice et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Treatment of IBD: Where We Are and Where We Are Going
- (2014) Charles N Bernstein AMERICAN JOURNAL OF GASTROENTEROLOGY
- Catestatin decreases macrophage function in two mouse models of experimental colitis
- (2014) Mohammad F. Rabbi et al. BIOCHEMICAL PHARMACOLOGY
- Polycomb-mediated loss of microRNA let-7c determines inflammatory macrophage polarization via PAK1-dependent NF-κB pathway
- (2014) W Zhang et al. CELL DEATH AND DIFFERENTIATION
- Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization
- (2014) Yuli Lin et al. Cellular & Molecular Immunology
- Linking Immunity, Epigenetics, and Cancer in Inflammatory Bowel Disease
- (2014) Jan Däbritz et al. INFLAMMATORY BOWEL DISEASES
- 3-Deazaneplanocin A (DZNep), an Inhibitor ofS-Adenosylmethionine-dependent Methyltransferase, Promotes Erythroid Differentiation
- (2014) Tohru Fujiwara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Immunosuppressive monocytes: possible homeostatic mechanism to restrain chronic intestinal inflammation
- (2014) Elvira Kurmaeva et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Regulation and Role of EZH2 in Cancer
- (2014) Hirohito Yamaguchi et al. Cancer Research and Treatment
- Infectious and Malignant Complications of TNF Inhibitor Therapy in IBD
- (2013) Laura E Targownik et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
- (2013) Eunhee Kim et al. CANCER CELL
- IDO1 Metabolites Activate β-catenin Signaling to Promote Cancer Cell Proliferation and Colon Tumorigenesis in Mice
- (2013) Ameet I. Thaker et al. GASTROENTEROLOGY
- Beyond Gene Discovery in Inflammatory Bowel Disease: The Emerging Role of Epigenetics
- (2013) Nicholas T. Ventham et al. GASTROENTEROLOGY
- The Polycomb Protein Ezh2 Regulates Differentiation and Plasticity of CD4+ T Helper Type 1 and Type 2 Cells
- (2013) Damon J. Tumes et al. IMMUNITY
- Tumor Necrosis Factor-α Blocks Differentiation and Enhances Suppressive Activity of Immature Myeloid Cells during Chronic Inflammation
- (2013) Moshe Sade-Feldman et al. IMMUNITY
- The role and potential therapeutic application of myeloid-derived suppressor cells in TNBS-induced colitis
- (2013) Qingdong Guan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- TNF signaling drives myeloid-derived suppressor cell accumulation
- (2012) Xueqiang Zhao et al. JOURNAL OF CLINICAL INVESTIGATION
- Transplantation of granulocytic myeloid-derived suppressor cells (G-MDSCs) could reduce colitis in experimental murine models
- (2012) Hui Su et al. Journal of Digestive Diseases
- Mouse CD11b + Gr-1 + Myeloid Cells Can Promote Th17 Cell Differentiation and Experimental Autoimmune Encephalomyelitis
- (2012) Huanfa Yi et al. JOURNAL OF IMMUNOLOGY
- Ly6C+Ly6G−Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury
- (2012) Hirokazu Saiwai et al. JOURNAL OF NEUROCHEMISTRY
- EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
- (2012) Michael T. McCabe et al. NATURE
- Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
- (2012) A. Herrera-Merchan et al. Nature Communications
- Investigating Intestinal Inflammation in DSS-induced Model of IBD
- (2012) Janice J. Kim et al. Jove-Journal of Visualized Experiments
- Intestinal Inflammation and Cancer
- (2011) Thomas A. Ullman et al. GASTROENTEROLOGY
- Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions
- (2009) Chen Varol et al. IMMUNITY
- DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
- (2009) T. B. Miranda et al. MOLECULAR CANCER THERAPEUTICS
- Myeloid-Derived Suppressor Cells in Inflammatory Bowel Disease: A New Immunoregulatory Pathway
- (2008) Lydia A. Haile et al. GASTROENTEROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now