The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease

Alterations in Synaptic Function and Plasticity in Huntington Disease

(2019) Amy I. Smith‐Dijak et al.   JOURNAL OF NEUROCHEMISTRY

Region- and activity-dependent regulation of extracellular glutamate

(2018) Nawrin F. Pinky et al.   JOURNAL OF NEUROSCIENCE

Huntingtin suppression restores cognitive function in a mouse model of Huntington’s disease

(2018) Amber L. Southwell et al.   Science Translational Medicine

Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models

(2018) Hongyu Zhang et al.   Nature Communications

Endocannabinoid-Specific Impairment in Synaptic Plasticity in Striatum of Huntington's Disease Mouse Model

(2017) Marja D. Sepers et al.   JOURNAL OF NEUROSCIENCE

Therapies targeting DNA and RNA in Huntington's disease

(2017) Edward J Wild et al.   LANCET NEUROLOGY

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington’s disease model

(2017) Albert Giralt et al.   Nature Communications

Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis

(2017) Paula Dietrich et al.   PLoS Genetics

An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes

(2016) Amber L. Southwell et al.   HUMAN MOLECULAR GENETICS

Calcium-Dependent Protein Kinase C Is Not Required for Post-Tetanic Potentiation at the Hippocampal CA3 to CA1 Synapse

(2016) Chih-Chieh Wang et al.   JOURNAL OF NEUROSCIENCE

Autocrine BDNF–TrkB signalling within a single dendritic spine

(2016) Stephen C. Harward et al.   NATURE

Different Patterns of Electrical Activity Lead to Long-term Potentiation by Activating Different Intracellular Pathways

(2015) G. Zhu et al.   JOURNAL OF NEUROSCIENCE

Huntington disease: natural history, biomarkers and prospects for therapeutics

(2014) Christopher A. Ross et al.   Nature Reviews Neurology

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders

(2014) Matthew P. Parsons et al.   NEURON

Striatal Synaptic Dysfunction and Hippocampal Plasticity Deficits in the Hu97/18 Mouse Model of Huntington Disease

(2014) Karolina Kolodziejczyk et al.   PLoS One

Mutant Huntingtin Alters Retrograde Transport of TrkB Receptors in Striatal Dendrites

(2013) G. Liot et al.   JOURNAL OF NEUROSCIENCE

Prostaglandin E2 EP1 Receptor Antagonist Improves Motor Deficits and Rescues Memory Decline in R6/1 Mouse Model of Huntington's Disease

(2013) Marta Anglada-Huguet et al.   MOLECULAR NEUROBIOLOGY

Multisource ascertainment of Huntington disease in Canada: Prevalence and population at risk

(2013) Emily R. Fisher et al.   MOVEMENT DISORDERS

Choosing an animal model for the study of Huntington's disease

(2013) Mahmoud A. Pouladi et al.   NATURE REVIEWS NEUROSCIENCE

BDNF mechanisms in late LTP formation: A synthesis and breakdown

(2013) Debabrata Panja et al.   NEUROPHARMACOLOGY

Performing Vaginal Lavage, Crystal Violet Staining, and Vaginal Cytological Evaluation for Mouse Estrous Cycle Staging Identification

(2012) Ashleigh C. McLean et al.   Jove-Journal of Visualized Experiments

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

(2011) Albert Giralt et al.   HUMAN MOLECULAR GENETICS

Modulation of synaptic plasticity in the hippocampus by hippocampus-derived estrogen and androgen

(2011) Yuuki Ooishi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function

(2011) L.A. Raymond et al.   NEUROSCIENCE

Enhancement of AMPA currents and GluR1 membrane expression through PKA-coupled adenosine A2A receptors

(2010) Raquel B. Dias et al.   HIPPOCAMPUS

Mild cognitive impairment in prediagnosed Huntington disease

(2010) K. Duff et al.   NEUROLOGY

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

(2010) Austen J. Milnerwood et al.   TRENDS IN NEUROSCIENCES

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

(2009) Shu-ichi Okamoto et al.   NATURE MEDICINE

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

(2009) D. A. Simmons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of Huntington's disease decades before diagnosis: the Predict-HD study

(2007) J S Paulsen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY