Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs
出版年份 2019 全文链接
标题
Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs
作者
关键词
-
出版物
MOLECULAR PHARMACOLOGY
Volume 96, Issue 2, Pages 272-296
出版商
American Society for Pharmacology & Experimental Therapeutics (ASPET)
发表日期
2019-06-21
DOI
10.1124/mol.119.116202
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- (2018) Sifat Maria et al. JOURNAL OF PINEAL RESEARCH
- Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
- (2017) Yalikun Suofu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of resistance to endocrine therapy in breast cancer: the important role of PI3K/Akt/mTOR in estrogen receptor-positive, HER2-negative breast cancer
- (2017) Kazuhiro Araki et al. Breast Cancer
- A Novel Strategy to Co-target Estrogen Receptor and Nuclear Factor κB Pathways with Hybrid Drugs for Breast Cancer Therapy
- (2017) Irida Kastrati et al. Hormones & Cancer
- Sustained release of melatonin: A novel approach in elevating efficacy of tamoxifen in breast cancer treatment
- (2016) Mehdi Sabzichi et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- The MEK5/ERK5 signalling pathway in cancer: a promising novel therapeutic target
- (2016) André E.S. Simões et al. DRUG DISCOVERY TODAY
- Melatonin: an inhibitor of breast cancer
- (2015) S. M. Hill et al. ENDOCRINE-RELATED CANCER
- Dual Inhibition of MEK and PI3K Pathway in KRAS and BRAF Mutated Colorectal Cancers
- (2015) Sally Temraz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology
- (2014) Elyes Dahmane et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Pharmacokinetics of endoxifen and tamoxifen in female mice: implications for comparative in vivo activity studies
- (2014) Joel M. Reid et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Circadian and Melatonin Disruption by Exposure to Light at Night Drives Intrinsic Resistance to Tamoxifen Therapy in Breast Cancer
- (2014) R. T. Dauchy et al. CANCER RESEARCH
- High affinity nuclear and nongenomic estradiol binding sites in the human and mouse lens
- (2013) M. Rachel Kirker et al. EXPERIMENTAL EYE RESEARCH
- Histone Deacetylase Inhibitors Equipped with Estrogen Receptor Modulation Activity
- (2013) Berkley E. Gryder et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tamoxifen Resistance in Breast Cancer
- (2012) Min-Sun Chang Biomolecules & Therapeutics
- Clinical and biomarker predictors of side effects from tamoxifen
- (2011) Wendy Lorizio et al. BREAST CANCER RESEARCH AND TREATMENT
- Activation of the ERK1/2 Mitogen-Activated Protein Kinase Cascade by Dentin Matrix Protein 1 Promotes Osteoblast Differentiation
- (2011) Asha Eapen et al. CELLS TISSUES ORGANS
- Melatonin osteoporosis prevention study (MOPS): a randomized, double-blind, placebo-controlled study examining the effects of melatonin on bone health and quality of life in perimenopausal women
- (2011) Mary P. Kotlarczyk et al. JOURNAL OF PINEAL RESEARCH
- Long-Term Outcomes of Invasive Ipsilateral Breast Tumor Recurrences After Lumpectomy in NSABP B-17 and B-24 Randomized Clinical Trials for DCIS
- (2011) I. L. Wapnir et al. JNCI-Journal of the National Cancer Institute
- How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
- (2010) Yohannes Mebratu et al. CELL CYCLE
- Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways
- (2010) Shalini Sethi et al. JOURNAL OF PINEAL RESEARCH
- Stimulating the GPR30 Estrogen Receptor with a Novel Tamoxifen Analogue Activates SF-1 and Promotes Endometrial Cell Proliferation
- (2009) Benjamin C. Lin et al. CANCER RESEARCH
- Melatonin and breast cancer: cellular mechanisms, clinical studies and future perspectives
- (2009) Stephen G. Grant et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Molecular Mechanisms of Melatonin Anticancer Effects
- (2009) Steven M. Hill et al. INTEGRATIVE CANCER THERAPIES
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