Control of specific growth rate for the enhanced production of human interferon α2b in glycoengineered Pichia pastoris : process analytical technology guided approach

High level extracellular production of recombinant human interferon alpha 2b in glycoengineered Pichia pastoris: culture medium optimization, high cell density cultivation and biological characterization

(2019) S. Katla et al.   JOURNAL OF APPLIED MICROBIOLOGY

Novel glycosylated human interferon alpha 2b expressed in glycoengineered Pichia pastoris and its biological activity: N-linked glycoengineering approach

(2019) Srikanth Katla et al.   ENZYME AND MICROBIAL TECHNOLOGY

Cultivation strategies to enhance productivity of Pichia pastoris: A review

(2015) V. Looser et al.   BIOTECHNOLOGY ADVANCES

Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture

(2015) Julia Caldwell et al.   PLoS One

The Application of Dielectric Spectroscopy and Biocalorimetry for the Monitoring of Biomass in Immobilized Mammalian Cell Cultures

(2015) Harriet Cole et al.   Processes

Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production

(2014) Mudassar Ahmad et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Advanced near-infrared monitor for stable real-time measurement and control ofPichia pastorisbioprocesses

(2014) Marina Goldfeld et al.   BIOTECHNOLOGY PROGRESS

A supervision and control tool based on artificial intelligence for high cell density cultivations

(2014) A. C. L. Horta et al.   BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING

Expression of recombinant human mast cell chymase with Asn-linked glycans in glycoengineered Pichia pastoris

(2014) Eliot T. Smith et al.   PROTEIN EXPRESSION AND PURIFICATION

InPichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response

(2013) Corinna Rebnegger et al.   Biotechnology Journal

Real-time monitoring and control of microbial bioprocesses with focus on the specific growth rate: current state and perspectives

(2012) Moira Monika Schuler et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Application of adaptive DO-stat feeding control to Pichia pastoris X33 cultures expressing a single chain antibody fragment (scFv)

(2012) A. R. Ferreira et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes

(2012) Patrick Wechselberger et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Dynamic modeling of methylotrophic Pichia pastoris culture with exhaust gas analysis: From cellular metabolism to process simulation

(2012) Hongxing Niu et al.   CHEMICAL ENGINEERING SCIENCE

Protein secretion in Pichia pastoris and advances in protein production

(2011) Leonardo M. Damasceno et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Investigation of the potential of biocalorimetry as a process analytical technology (PAT) tool for monitoring and control of Crabtree-negative yeast cultures

(2011) Moira Monika Schuler et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Introducing process analytical technology (PAT) in filamentous cultivation process development: comparison of advanced online sensors for biomass measurement

(2011) Nanna Petersen Rønnest et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, Yarrowia lipolytica

(2011) Najla Gasmi et al.   Microbial Cell Factories

Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment

(2011) D. Levin et al.   MOLECULAR AND CELLULAR BIOLOGY

High efficient production of recombinant human consensus interferon mutant in high cell density culture of Pichia pastoris using two phases methanol control

(2011) Dan Wu et al.   PROCESS BIOCHEMISTRY

Catabolite Repression of Aox in Pichia pastoris Is Dependent on Hexose Transporter PpHxt1 and Pexophagy

(2010) P. Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Simple control of specific growth rate in biotechnological fed-batch processes based on enhanced online measurements of biomass

(2010) Michal Dabros et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Antibody expression kinetics in glycoengineered Pichia pastoris

(2010) Thomas I. Potgieter et al.   BIOTECHNOLOGY AND BIOENGINEERING

A novel pattern-based approach for diagnostic controller performance monitoring

(2010) Rachelle Howard et al.   CONTROL ENGINEERING PRACTICE

Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate

(2010) Pieter P Jacobs et al.   Microbial Cell Factories

Strategies to maximize expression of rightly processed human interferon α2b in Pichia pastoris

(2010) Shardul Salunkhe et al.   PROTEIN EXPRESSION AND PURIFICATION

Cole–Cole, linear and multivariate modeling of capacitance data for on-line monitoring of biomass

(2008) Michal Dabros et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Transcription factor control of growth rate dependent genes in Saccharomyces cerevisiae: A three factor design

(2008) Alessandro Fazio et al.   BMC GENOMICS

On-line monitoring of lipid storage in yeasts using impedance spectroscopy

(2008) Thomas Maskow et al.   JOURNAL OF BIOTECHNOLOGY

Secretory expression of interferon-alpha 2b in recombinant Pichia pastoris using three different secretion signals

(2008) Anand Ghosalkar et al.   PROTEIN EXPRESSION AND PURIFICATION

High level production and purification of human interferon α2b in high cell density culture of Pichia pastoris

(2007) Atef Ayed et al.   ENZYME AND MICROBIAL TECHNOLOGY