Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus

Interaction between FKBP5 gene and childhood trauma on psychosis, depression and anxiety symptoms in a non-clinical sample

(2017) Marta de Castro-Catala et al.   PSYCHONEUROENDOCRINOLOGY

STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5

(2016) Negar Fani et al.   DEPRESSION AND ANXIETY

FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children

(2016) Sandra Scheuer et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Timing and crosstalk of glucocorticoid signaling with cytokines, neurotransmitters and growth factors

(2016) Margarita Arango-Lievano et al.   PHARMACOLOGICAL RESEARCH

Associations between the FKBP5 haplotype, exposure to violence and anxiety in females

(2016) Johan Isaksson et al.   PSYCHONEUROENDOCRINOLOGY

FKBP5/FKBP51 enhances autophagy to synergize with antidepressant action

(2015) Nils C Gassen et al.   Autophagy

Estrogen and Extinction of Fear Memories:Implications for Posttraumatic Stress Disorder Treatment

(2015) Ebony M. Glover et al.   BIOLOGICAL PSYCHIATRY

HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS

(2015) Susanna Roberts et al.   DEPRESSION AND ANXIETY

Sex differences in anxiety disorders: Interactions between fear, stress, and gonadal hormones

(2015) Lisa Y. Maeng et al.   HORMONES AND BEHAVIOR

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

(2015) J. Hartmann et al.   JOURNAL OF NEUROSCIENCE

FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications

(2015) N C Gassen et al.   MOLECULAR PSYCHIATRY

Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions

(2015) Torsten Klengel et al.   NEURON

Gene–Stress–Epigenetic Regulation of FKBP5: Clinical and Translational Implications

(2015) Anthony S Zannas et al.   NEUROPSYCHOPHARMACOLOGY

Expression of amygdala mineralocorticoid receptor and glucocorticoid receptor in the single-prolonged stress rats

(2014) Fang Han et al.   BMC NEUROSCIENCE

Differential impact of chronic stress along the hippocampal dorsal–ventral axis

(2014) V. Pinto et al.   Brain Structure & Function

Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

(2014) Jonathan J. Sabbagh et al.   PLoS One

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

(2014) Nils C. Gassen et al.   PLOS MEDICINE

Early-life stress affects the structural and functional plasticity of the medial prefrontal cortex in adolescent rats

(2013) Agnieszka Chocyk et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression

(2013) A. Menke et al.   GENES BRAIN AND BEHAVIOR

Prepulse inhibition in psychiatric disorders – Apart from schizophrenia

(2013) S. Kohl et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The three-hit concept of vulnerability and resilience: Toward understanding adaptation to early-life adversity outcome

(2013) Nikolaos P. Daskalakis et al.   PSYCHONEUROENDOCRINOLOGY

Neural regulation of the stress response: glucocorticoid feedback mechanisms

(2012) J.P. Herman et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Interaction ofFKBP5Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study

(2011) Petra Zimmermann et al.   AMERICAN JOURNAL OF PSYCHIATRY

Prevalence, Persistence, and Sociodemographic Correlates of DSM-IV Disorders in the National Comorbidity Survey Replication Adolescent Supplement

(2011) Shelli Avenevoli   ARCHIVES OF GENERAL PSYCHIATRY

Gender differences in anxiety disorders: Prevalence, course of illness, comorbidity and burden of illness

(2011) Carmen P. McLean et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Lifetime Prevalence of Mental Disorders in U.S. Adolescents: Results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A)

(2011) Kathleen Ries Merikangas et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Expression and Regulation of the Fkbp5 Gene in the Adult Mouse Brain

(2011) Sebastian H. Scharf et al.   PLoS One

A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51

(2011) John C. O'Leary et al.   PLoS One

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder

(2011) Amy L. Mahan et al.   TRENDS IN NEUROSCIENCES

Childhood Adversities and Adult Psychiatric Disorders in the National Comorbidity Survey Replication II

(2010) Katie A. McLaughlin et al.   ARCHIVES OF GENERAL PSYCHIATRY

Childhood Adversities and Adult Psychiatric Disorders in the National Comorbidity Survey Replication I

(2010) Jennifer Greif Green et al.   ARCHIVES OF GENERAL PSYCHIATRY

Maternal separation stress leads to enhanced emotional responses to noxious stimuli in adult rats

(2010) Megan L. Uhelski et al.   BEHAVIOURAL BRAIN RESEARCH

Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys

(2010) Ronald C. Kessler et al.   BRITISH JOURNAL OF PSYCHIATRY

Sex Differences in Stress Response Circuitry Activation Dependent on Female Hormonal Cycle

(2010) J. M. Goldstein et al.   JOURNAL OF NEUROSCIENCE

Relationships between psychological distress, coping styles, and HPA axis reactivity in healthy adults

(2010) Hiroaki Hori et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

(2009) Huadong Pei et al.   CANCER CELL

CaMKII knockdown attenuates H2O2-induced phosphorylation of ERK1/2, PKB/Akt, and IGF-1R in vascular smooth muscle cells

(2009) Ali Bouallegue et al.   FREE RADICAL BIOLOGY AND MEDICINE