FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications

Selective inhibitors of the FK506-binding protein 51 by induced fit

(2014) Steffen Gaali et al.   Nature Chemical Biology

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans

(2014) Nils C. Gassen et al.   PLOS MEDICINE

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Kainic Acid-Induced Seizures Modulate Akt (SER473) Phosphorylation in the Hippocampus of Dopamine D2 Receptor Knockout Mice

(2012) Mark Dunleavy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Differences in FKBP51 Regulation Following Chronic Social Defeat Stress Correlate with Individual Stress Sensitivity: Influence of Paroxetine Treatment

(2012) Klaus V Wagner et al.   NEUROPSYCHOPHARMACOLOGY

FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior

(2011) Chadi Touma et al.   BIOLOGICAL PSYCHIATRY

Functional significance of glycogen synthase kinase-3 regulation by serotonin

(2011) Abigail M. Polter et al.   CELLULAR SIGNALLING

P.1.024 The epigenetic machinery of neural cells is modulated by psychoactive drugs

(2011) N. Zimmermann et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling

(2011) J C Garza et al.   MOLECULAR PSYCHIATRY

Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodeling

(2011) Xiao-Dong Wang et al.   NEUROBIOLOGY OF DISEASE

The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress

(2011) Jakob Hartmann et al.   NEUROPHARMACOLOGY

AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011

(2011) C. Hiemke et al.   PHARMACOPSYCHIATRY

ENPP1 Affects Insulin Action and Secretion: Evidences from In Vitro Studies

(2011) Rosa Di Paola et al.   PLoS One

A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51

(2011) John C. O'Leary et al.   PLoS One

Mice lacking phosphatase PP2A subunit PR61/B'  (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3 

(2011) J. V. Louis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition

(2011) M. V. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cdk5: Multitasking between physiological and pathological conditions

(2011) Joao P. Lopes et al.   PROGRESS IN NEUROBIOLOGY

Glycogen Synthase Kinase-3 in the Etiology and Treatment of Mood Disorders

(2011) Richard Scott Jope   Frontiers in Molecular Neuroscience

Lentivirally mediated GSK-3β silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice

(2010) Naoto Omata et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth

(2010) Héctor R. Quintá et al.   JOURNAL OF NEUROCHEMISTRY

The Hsp90 Cochaperone, FKBP51, Increases Tau Stability and Polymerizes Microtubules

(2010) U. K. Jinwal et al.   JOURNAL OF NEUROSCIENCE

Protein Phosphatase 2A and Glycogen Synthase Kinase 3 Signaling Modulate Prepulse Inhibition of the Acoustic Startle Response by Altering Cortical M-Type Potassium Channel Activity

(2010) D. Kapfhamer et al.   JOURNAL OF NEUROSCIENCE

Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters

(2010) Gabriela Schumann Burkard et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

GSK3 signalling in neural development

(2010) Eun-Mi Hur et al.   NATURE REVIEWS NEUROSCIENCE

Lithium: Still a Cornerstone in the Long-Term Treatment in Bipolar Disorder?

(2010) Alessandra M.A. Nivoli et al.   NEUROPSYCHOBIOLOGY

Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?

(2010) Xiaohua Li et al.   NEUROPSYCHOPHARMACOLOGY

Differential Impact of Tetratricopeptide Repeat Proteins on the Steroid Hormone Receptors

(2010) Jan-Philip Schülke et al.   PLoS One

A role for FKBP52 in Tau protein function

(2010) B. Chambraud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pituitary glucocorticoid receptor deletion reduces vulnerability to chronic stress

(2010) Klaus V. Wagner et al.   PSYCHONEUROENDOCRINOLOGY

FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt

(2009) Huadong Pei et al.   CANCER CELL

Trauma exposure and stress-related disorders in inner city primary care patients

(2009) Charles F. Gillespie et al.   GENERAL HOSPITAL PSYCHIATRY

Valproate and Amitriptyline Exert Common and Divergent Influences on Global and Gene Promoter-Specific Chromatin Modifications in Rat Primary Astrocytes

(2009) Tatjana Perisic et al.   NEUROPSYCHOPHARMACOLOGY

The FKBP5-Gene in Depression and Treatment Response—an Association Study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort

(2008) Magnus Lekman et al.   BIOLOGICAL PSYCHIATRY

A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior

(2008) Jean-Martin Beaulieu et al.   CELL

Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults

(2008) Elisabeth B. Binder   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

GSK-3β in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1–dependent mechanism

(2008) Mohit Kapoor et al.   JOURNAL OF CLINICAL INVESTIGATION

Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: A review

(2008) M. F. B. Silva et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Clinical characteristics and treatment outcome in a representative sample of depressed inpatients – Findings from the Munich Antidepressant Response Signature (MARS) project

(2008) Johannes M. Hennings et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Family-based association of FKBP5 in bipolar disorder

(2008) V L Willour et al.   MOLECULAR PSYCHIATRY

Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice

(2008) Angelo O. Rosa et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY