An in vitro attempt at precision toxicology reveals the involvement of DNA methylation alteration in ochratoxin A-induced G0/G1 phase arrest

Microchip-based single-cell functional proteomics for biomedical applications

(2017) Yao Lu et al.   LAB ON A CHIP

Feedback inhibition of CREB signaling by p38 MAPK contributes to the negative regulation of steroidogenesis

(2017) Jiaxin Li et al.   Reproductive Biology and Endocrinology

Ochratoxin A induced premature senescence in human renal proximal tubular cells

(2017) Xuan Yang et al.   TOXICOLOGY

Single-Cell Multiomics: Multiple Measurements from Single Cells

(2017) Iain C. Macaulay et al.   TRENDS IN GENETICS

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

(2016) Diego Adhemar Jaitin et al.   CELL

PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements

(2016) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Advances in research of nephrotoxicity and toxic antagonism of ochratoxin A

(2016) Tao Zhao et al.   Toxin Reviews

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

(2015) Shashank Tripathi et al.   Cell Host & Microbe

Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing

(2015) Hongshan Guo et al.   Nature Protocols

Dynamic changes of global DNA methylation and hypermethylation of cell adhesion-related genes in rat kidneys in response to ochratoxin A

(2015) X. Li et al.   World Mycotoxin Journal

Apoptosis Signal-regulating Kinase 1 promotes Ochratoxin A-induced renal cytotoxicity

(2015) Rui Liang et al.   Scientific Reports

Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells

(2014) Zeynep Özcan et al.   ARCHIVES OF TOXICOLOGY

Protective effect of N-acetylcysteine against DNA damage and S-phase arrest induced by ochratoxin A in human embryonic kidney cells (HEK-293)

(2014) Qian Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Central role of Nix in the autophagic response to ochratoxin A

(2014) Xiao Li Shen et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective role of the mitochondrial Lon protease 1 in ochratoxin A-induced cytotoxicity in HEK293 cells

(2014) Boyang Zhang et al.   Journal of Proteomics

DNA damage and S phase arrest induced by Ochratoxin A in human embryonic kidney cells (HEK 293)

(2014) Qian Yang et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

The ubiquitin proteasome system — Implications for cell cycle control and the targeted treatment of cancer

(2013) Florian Bassermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

BS-Seeker2: a versatile aligning pipeline for bisulfite sequencing data

(2013) Weilong Guo et al.   BMC GENOMICS

Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer

(2013) Jianan Gong et al.   CARCINOGENESIS

The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells

(2013) Bettina Maier et al.   CELL CYCLE

Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing

(2013) H. Guo et al.   GENOME RESEARCH

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Control of cell cycle transcription during G1 and S phases

(2013) Cosetta Bertoli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene

(2012) C Xuan et al.   ONCOGENE

Ochratoxin A induces oxidative DNA damage and G1 phase arrest in human peripheral blood mononuclear cells in vitro

(2012) Jing Liu et al.   TOXICOLOGY LETTERS

Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4Cdt2 Ubiquitin Ligase Complex

(2011) E. Shibata et al.   MOLECULAR AND CELLULAR BIOLOGY

PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update

(2011) X. Wang et al.   NUCLEIC ACIDS RESEARCH

A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38  with the MAPK Binding Domain of the Phosphatase MKP5

(2011) Y.-Y. Zhang et al.   Science Signaling

Ochratoxin A at nanomolar concentration perturbs the homeostasis of neural stem cells in highly differentiated but not in immature three-dimensional brain cell cultures

(2011) Marie-Gabrielle Zurich et al.   TOXICOLOGY LETTERS

ERK and p38 MAPK signaling pathways are involved in ochratoxin A-induced G2 phase arrest in human gastric epithelium cells

(2011) Yuan Wang et al.   TOXICOLOGY LETTERS

The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27

(2010) Ziguo Zhang et al.   EMBO JOURNAL

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

(2009) William E Tidyman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Notch Signaling: The Core Pathway and Its Posttranslational Regulation

(2009) Mark E. Fortini   DEVELOPMENTAL CELL

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders

(2008) Yoko Aoki et al.   HUMAN MUTATION

A Novel Protein, Luman/CREB3 Reruitment Factor, Inhibits Luman Activation of the Unfolded Protein Response

(2008) T. E. Audas et al.   MOLECULAR AND CELLULAR BIOLOGY