Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

(2016) Linda S. Steelman et al.   Aging-US

Oxidative DNA damage is involved in ochratoxin A-induced G2 arrest through ataxia telangiectasia-mutated (ATM) pathways in human gastric epithelium GES-1 cells in vitro

(2013) Jinfeng Cui et al.   ARCHIVES OF TOXICOLOGY

Ochratoxin A-induced cell proliferation and tumor promotion in mouse skin by activating the expression of cyclin-D1 and cyclooxygenase-2 through nuclear factor-kappa B and activator protein-1

(2012) R. Kumar et al.   CARCINOGENESIS

Topical Application of Ochratoxin A Causes DNA Damage and Tumor Initiation in Mouse Skin

(2012) Rahul Kumar et al.   PLoS One

Ochratoxin A and Mitotic Disruption: Mode of Action Analysis of Renal Tumor Formation by Ochratoxin A

(2012) Angela Mally   TOXICOLOGICAL SCIENCES

Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model

(2011) Paul Jennings et al.   ARCHIVES OF TOXICOLOGY

p53 activation inhibits ochratoxin A-induced apoptosis in monkey and human kidney epithelial cells via suppression of JNK activation

(2011) Jinghua Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual Blockade of EGFR and c-Met Abrogates Redundant Signaling and Proliferation in Head and Neck Carcinoma Cells

(2011) H. Xu et al.   CLINICAL CANCER RESEARCH

HGF-independent potentiation of EGFR action by c-Met

(2011) A M Dulak et al.   ONCOGENE

ERK and p38 MAPK signaling pathways are involved in ochratoxin A-induced G2 phase arrest in human gastric epithelium cells

(2011) Yuan Wang et al.   TOXICOLOGY LETTERS

Ochratoxin A and Aristolochic Acid Involvement in Nephropathies and Associated Urothelial Tract Tumours

(2010) Annie Pfohl-Leszkowicz   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

Signaling pathways in renal cell carcinoma

(2010) Gowrishankar Banumathy et al.   CANCER BIOLOGY & THERAPY

Receptor Tyrosine Kinase Coactivation Networks in Cancer

(2010) A. M. Xu et al.   CANCER RESEARCH

The genetic basis of kidney cancer: a metabolic disease

(2010) W. Marston Linehan et al.   Nature Reviews Urology

Evaluation of a urinary kidney biomarker panel in rat models of acute and subchronic nephrotoxicity

(2010) Dana Hoffmann et al.   TOXICOLOGY

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA

(2010) Jamie E. Jennings-Gee et al.   Toxins

Activation of the PI3K/AKT Pathway Induces Urothelial Carcinoma of the Renal Pelvis: Identification in Human Tumors and Confirmation in Animal Models

(2009) C.-N. Qian et al.   CANCER RESEARCH

Noncatalytic Function of ERK1/2 Can Promote Raf/MEK/ERK-mediated Growth Arrest Signaling

(2009) Seung-Keun Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Proteome response to ochratoxin A-induced apoptotic cell death in mouse hippocampal HT22 cells

(2009) Somy Yoon et al.   NEUROTOXICOLOGY

Low doses of ochratoxin A upregulate the protein expression of organic anion transporters Oat1, Oat2, Oat3 and Oat5 in rat kidney cortex

(2009) Vilim Žlender et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The role of stress-activated protein kinase signaling in renal pathophysiology

(2008) F.Y. Ma et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

In Vitro Cytogenetic Results Supporting a DNA Nonreactive Mechanism for Ochratoxin A, Potentially Relevant for Its Carcinogenicity

(2008) Pasquale Mosesso et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy

(2008) Stuart Thomson et al.   CLINICAL & EXPERIMENTAL METASTASIS

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE