Multi-omics profiling of calcium-induced human keratinocytes differentiation reveals modulation of unfolded protein response signaling pathways

Calcium signaling at the endoplasmic reticulum: fine-tuning stress responses

(2018) Amado Carreras-Sureda et al.   CELL CALCIUM

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Orchestrated control of filaggrin–actin scaffolds underpins cornification

(2018) Danuta Gutowska-Owsiak et al.   Cell Death & Disease

Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation

(2018) Judit Bigas et al.   Cell Death & Disease

Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis

(2018) Stephen J. Goldie et al.   Cell Death & Disease

Sublethal UV irradiation induces squamous differentiation via a p53-independent, DNA damage-mitosis checkpoint

(2018) Isabel de Pedro et al.   Cell Death & Disease

Plau and Tgfbr3 are YAP-regulated genes that promote keratinocyte proliferation

(2018) Susan M. Corley et al.   Cell Death & Disease

C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event

(2018) Zachary J. Messenger et al.   Cell Death & Disease

Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress

(2017) Dan Xia et al.   Cell Death & Disease

PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)

(2017) Philip Kranz et al.   Cell Death & Disease

Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells

(2016) Lichao Zhang et al.   BMC BIOTECHNOLOGY

Critical role of X-box binding protein 1 in NADPH oxidase 4-triggered cardiac hypertrophy is mediated by receptor interacting protein kinase 1

(2016) Li Chen et al.   CELL CYCLE

Human hair-follicle associated pluripotent (hHAP) stem cells differentiate to cardiac-muscle cells

(2016) Natsuko Tohgi et al.   CELL CYCLE

HSP70 dependence in rhabdomyosarcoma: Seed or soil?

(2016) Amit J. Sabnis et al.   CELL CYCLE

p53 on the crossroad between regeneration and cancer

(2016) Meital Charni et al.   CELL DEATH AND DIFFERENTIATION

Luteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis and inflammation in keratinocytes and in mouse psoriatic model

(2016) R Palombo et al.   Cell Death & Disease

Regulation of Translation Factor EEF1D Gene Function by Alternative Splicing

(2015) Taku Kaitsuka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Characterization and Mechanism of Stress-induced Translocation of 78-Kilodalton Glucose-regulated Protein (GRP78) to the Cell Surface

(2015) Yuan-Li Tsai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins

(2015) Reneé Higgins et al.   MOLECULAR CELL

p63 supports aerobic respiration through hexokinase II

(2015) Guiditta Viticchiè et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the β-catenin signaling

(2015) Zongwei Li et al.   Oncotarget

Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense

(2015) Angelo D’Alessandro et al.   Oncotarget

Differential activity of rice protein disulfide isomerase family members for disulfide bond formation and reduction

(2014) Yayoi Onda et al.   FEBS Open Bio

Epidermal Differentiation in Barrier Maintenance and Wound Healing

(2014) Tongyu Cao Wikramanayake et al.   Advances in Wound Care

Concurrent regulation of the transcription factors Nrf2 and ATF4 mediates the enhancement of glutathione levels by the flavonoid fisetin

(2013) Jennifer L. Ehren et al.   BIOCHEMICAL PHARMACOLOGY

Cell death by cornification

(2013) Leopold Eckhart et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

p63 regulates glutaminase 2 expression

(2013) Giacobbe Arianna et al.   CELL CYCLE

Cellular metabolic and autophagic pathways: Traffic control by redox signaling

(2013) Matthew Dodson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Unfolded protein response in keratinocytes: Impact on normal and abnormal keratinization

(2013) Kazumitsu Sugiura   JOURNAL OF DERMATOLOGICAL SCIENCE

Bidirectional binding property of high glycine–tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair

(2013) Ryo Matsunaga et al.   JOURNAL OF STRUCTURAL BIOLOGY

Optimal Differentiation of In Vitro Keratinocytes Requires Multifactorial External Control

(2013) Anne-Sophie Borowiec et al.   PLoS One

Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response

(2013) B. M. Gardner et al.   Cold Spring Harbor Perspectives in Biology

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

(2013) Matthew D. Shoulders et al.   Cell Reports

Dermokine-β impairs ERK signaling through direct binding to GRP78

(2012) Kiyoshi Higashi et al.   FEBS LETTERS

Expression and Functional Studies on the Noncoding RNA, PRINS

(2012) Krisztina Szegedi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

(2012) B Luo et al.   ONCOGENE

p63-microRNA feedback in keratinocyte senescence

(2012) P. Rivetti di Val Cervo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The many roles of the eukaryotic elongation factor 1 complex

(2012) Arjun N. Sasikumar et al.   Wiley Interdisciplinary Reviews-RNA

Protein Folding and Modification in the Mammalian Endoplasmic Reticulum

(2011) Ineke Braakman et al.   Annual Review of Biochemistry

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

(2011) Min Ni et al.   BIOCHEMICAL JOURNAL

ER stress modulates cellular metabolism

(2011) Xiaoli Wang et al.   BIOCHEMICAL JOURNAL

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

Quality and quantity control at the endoplasmic reticulum

(2010) Ramanujan S Hegde et al.   CURRENT OPINION IN CELL BIOLOGY

Disulphide production by Ero1α–PDI relay is rapid and effectively regulated

(2010) Christian Appenzeller-Herzog et al.   EMBO JOURNAL

The ubiquitin receptor Rad23: At the crossroads of nucleotide excision repair and proteasomal degradation

(2009) Nico P. Dantuma et al.   DNA REPAIR

Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco–Sjögren syndrome

(2009) Lihong Zhao et al.   HUMAN MOLECULAR GENETICS

Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways

(2009) J A Kelber et al.   ONCOGENE

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum

(2008) Yusuke Adachi et al.   CELL STRUCTURE AND FUNCTION

p63 in epithelial development

(2008) E. Candi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE