A model for the aberrant DNA methylomes in aging cells and cancer cells

Age-dependent DNA methylation patterns on the Y chromosome in elderly males

(2019) Jesper B. Lund et al.   AGING CELL

Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation

(2018) Rauf Ahmad Najar et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dynamics and function of DNA methylation in plants

(2018) Huiming Zhang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of DNA methylation in ageing and cancer

(2018) A. E. Morgan et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

DNA Methylation Clocks in Aging: Categories, Causes, and Consequences

(2018) Adam E. Field et al.   MOLECULAR CELL

A methylated-DNA-binding complex required for plant development mediates transcriptional activation of promoter methylated genes

(2018) Qiang-Qiang Zhao et al.   Journal of Integrative Plant Biology

A Group of SUVH Methyl-DNA Binding Proteins Regulate Expression of the DNA Demethylase ROS1 in Arabidopsis

(2018) Xinlong Xiao et al.   Journal of Integrative Plant Biology

Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma

(2017) Rui-hua Xu et al.   NATURE MATERIALS

TET-mediated active DNA demethylation: mechanism, function and beyond

(2017) Xiaoji Wu et al.   NATURE REVIEWS GENETICS

Epigenetics and Oxidative Stress in Aging

(2017) Amy Guillaumet-Adkins et al.   Oxidative Medicine and Cellular Longevity

Critical roles of DNA demethylation in the activation of ripening-induced genes and inhibition of ripening-repressed genes in tomato fruit

(2017) Zhaobo Lang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA methylation markers for diagnosis and prognosis of common cancers

(2017) Xiaoke Hao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Aging Epigenome

(2016) Lauren N. Booth et al.   MOLECULAR CELL

Epigenetic Determinants of Cancer

(2016) Stephen B. Baylin et al.   Cold Spring Harbor Perspectives in Biology

Mitochondrial dysfunction and oxidative stress in aging and cancer

(2016) Anna V. Kudryavtseva et al.   Oncotarget

Aging and DNA methylation

(2015) Marc Jung et al.   BMC BIOLOGY

Nascent Transcription Affected by RNA Polymerase IV in Zea mays

(2015) Karl F. Erhard et al.   GENETICS

Whole-genome fingerprint of the DNA methylome during human B cell differentiation

(2015) Marta Kulis et al.   NATURE GENETICS

DNA methylation pathways and their crosstalk with histone methylation

(2015) Jiamu Du et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A DEMETER-like DNA demethylase governs tomato fruit ripening

(2015) Ruie Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory link between DNA methylation and active demethylation inArabidopsis

(2015) Mingguang Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methylation-Sensitive Expression of a DNA Demethylase Gene Serves As an Epigenetic Rheostat

(2015) Ben P. Williams et al.   PLoS Genetics

Nascent Transcription Affected by RNA Polymerase IV in Zea mays

(2015) Karl F. Erhard et al.   GENETICS

DNA methylation abnormalities at gene promoters are extensive and variable in the elderly and phenocopy cancer cells

(2014) Hannah E. Gautrey et al.   FASEB JOURNAL

RNA-directed DNA methylation: an epigenetic pathway of increasing complexity

(2014) Marjori A. Matzke et al.   NATURE REVIEWS GENETICS

Mutation of a major CG methylase in rice causes genome-wide hypomethylation, dysregulated genome expression, and seedling lethality

(2014) L. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

(2014) Carola Weidner et al.   GENOME BIOLOGY

The Arabidopsis Nucleosome Remodeler DDM1 Allows DNA Methyltransferases to Access H1-Containing Heterochromatin

(2013) Assaf Zemach et al.   CELL

Proliferation-Dependent Alterations of the DNA Methylation Landscape Underlie Hematopoietic Stem Cell Aging

(2013) Isabel Beerman et al.   Cell Stem Cell

Single-base resolution methylomes of tomato fruit development reveal epigenome modifications associated with ripening

(2013) Silin Zhong et al.   NATURE BIOTECHNOLOGY

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Hypothesis: Environmental regulation of 5-hydroxymethylcytosine by oxidative stress

(2011) Nancy Chia et al.   Epigenetics

DNA methylation in cancer development, diagnosis and therapy--multiple opportunities for genotoxic agents to act as methylome disruptors or remediators

(2011) J. Lewandowska et al.   MUTAGENESIS

Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

(2011) T. Watanabe et al.   SCIENCE

Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa

(2010) Nigel J. Belshaw et al.   CARCINOGENESIS

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Active DNA Demethylation Mediated by DNA Glycosylases

(2009) Jian-Kang Zhu   Annual Review of Genetics

Chromatin dynamics during epigenetic reprogramming in the mouse germ line

(2008) Petra Hajkova et al.   NATURE

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE