Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

Elevated Dnmt3a Activity Promotes Polyposis in ApcMin Mice by Relaxing Extracellular Restraints on Wnt Signaling

(2009) Michael S. Samuel et al.   GASTROENTEROLOGY

Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa

(2008) N J Belshaw et al.   BRITISH JOURNAL OF CANCER

Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations

(2008) Stefania Segditsas et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Assessment of PLSDA cross validation

(2008) Johan A. Westerhuis et al.   Metabolomics

Epigenetic drivers and genetic passengers on the road to cancer

(2008) Carla Sawan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS