The role of DNA methylation in ageing and cancer

Dietary fatty acids modulate adipocyte TNFa production via regulation of its DNA promoter methylation levels

(2017) Eva García-Escobar et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Distinctions in gene-specific changes in DNA methylation in response to folic acid supplementation between women with normal weight and obesity

(2017) Hea Jin Park et al.   Obesity Research & Clinical Practice

Caloric restriction delays age-related methylation drift

(2017) Shinji Maegawa et al.   Nature Communications

DNA methylation alters transcriptional rates of differentially expressed genes and contributes to pathophysiology in mice fed a high fat diet

(2017) Pili Zhang et al.   Molecular Metabolism

Genome-Wide Methylation Analysis Identifies Specific Epigenetic Marks In Severely Obese Children

(2017) Delphine Fradin et al.   Scientific Reports

DNA-Methylation and Body Composition in Preschool Children: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study

(2017) Peter Rzehak et al.   Scientific Reports

Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation

(2016) A.E. Morgan et al.   AGEING RESEARCH REVIEWS

Short-term calorie restriction ameliorates genomewide, age-related alterations in DNA methylation

(2016) Chul Hong Kim et al.   AGING CELL

Mass Spectrometry Based Ultrasensitive DNA Methylation Profiling Using Target Fragmentation Assay

(2016) Xiang-Cheng Lin et al.   ANALYTICAL CHEMISTRY

Mathematically modelling the dynamics of cholesterol metabolism and ageing

(2016) A.E. Morgan et al.   BIOSYSTEMS

Role of TET enzymes in DNA methylation, development, and cancer

(2016) Kasper Dindler Rasmussen et al.   GENES & DEVELOPMENT

A deterministic oscillatory model of microtubule growth and shrinkage for differential actions of short chain fatty acids

(2016) Josephine Kilner et al.   Molecular BioSystems

A mathematical model of microbial folate biosynthesis and utilisation: implications for antifolate development

(2016) J. Enrique Salcedo-Sora et al.   Molecular BioSystems

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

(2016) J V Sanchez-Mut et al.   Translational Psychiatry

Dietary polyphenols, oxidative stress and antioxidant and anti-inflammatory effects

(2016) Hua Zhang et al.   Current Opinion in Food Science

Comparison Between Decitabine and Azacitidine for the Treatment of Myelodysplastic Syndrome: A Meta-Analysis With 1392 Participants

(2015) Mixue Xie et al.   Clinical Lymphoma Myeloma & Leukemia

Whole-genome bisulfite sequencing maps from multiple human tissues reveal novel CpG islands associated with tissue-specific regulation

(2015) Isabel Mendizabal et al.   HUMAN MOLECULAR GENETICS

Computationally Modeling Lipid Metabolism and Aging: A Mini-review

(2015) Mark T. Mc Auley et al.   Computational and Structural Biotechnology Journal

DNA Methylation-Guided Prediction of Clinical Failure in High-Risk Prostate Cancer

(2015) Kirill Litovkin et al.   PLoS One

eMethylsorb: rapid quantification of DNA methylation in cancer cells on screen-printed gold electrodes

(2014) Kevin M. Koo et al.   ANALYST

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

(2014) Xiaojing Yang et al.   CANCER CELL

Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

(2014) Deqiang Sun et al.   Cell Stem Cell

eMethylsorb: electrochemical quantification of DNA methylation at CpG resolution using DNA–gold affinity interactions

(2014) Abu Ali Ibn Sina et al.   CHEMICAL COMMUNICATIONS

Molecular inversion probe-based SPR biosensing for specific, label-free and real-time detection of regional DNA methylation

(2014) Laura G. Carrascosa et al.   CHEMICAL COMMUNICATIONS

Body mass index at early adulthood, subsequent weight change and cancer incidence and mortality

(2014) Xuesong Han et al.   INTERNATIONAL JOURNAL OF CANCER

Genomic Imprinting in Mammals

(2014) D. P. Barlow et al.   Cold Spring Harbor Perspectives in Biology

DNA methylation signatures link prenatal famine exposure to growth and metabolism

(2014) Elmar W. Tobi et al.   Nature Communications

Comparative analysis between azacitidine and decitabine for the treatment of myelodysplastic syndromes

(2013) Yun-Gyoo Lee et al.   BRITISH JOURNAL OF HAEMATOLOGY

A genome-wide methylation study on obesity

(2013) Xiaojing Xu et al.   Epigenetics

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

(2013) M. Stevens et al.   GENOME RESEARCH

Clonal intratumor heterogeneity of promoter hypermethylation in breast cancer by MS-MLPA

(2013) Cathy B Moelans et al.   MODERN PATHOLOGY

Cocoa Consumption Alters the Global DNA Methylation of Peripheral Leukocytes in Humans with Cardiovascular Disease Risk Factors: A Randomized Controlled Trial

(2013) Anna Crescenti et al.   PLoS One

A whole-body mathematical model of cholesterol metabolism and its age-associated dysregulation

(2012) Mark T Mc Auley et al.   BMC Systems Biology

Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate's Role

(2012) Krista S. Crider et al.   Advances in Nutrition

Single base extension reaction-based surface enhanced Raman spectroscopy for DNA methylation assay

(2011) Juan Hu et al.   BIOSENSORS & BIOELECTRONICS

CpG island methylation profiling in human salivary gland adenoid cystic carcinoma

(2011) Achim Bell et al.   CANCER

Epigenetic Deregulation Across Chromosome 2q14.2 Differentiates Normal from Prostate Cancer and Provides a Regional Panel of Novel DNA Methylation Cancer Biomarkers

(2011) J. Devaney et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells

(2011) V. Nandakumar et al.   CARCINOGENESIS

Spatially Restricted and Developmentally Dynamic Expression of Engrailed Genes in Multiple Cerebellar Cell Types

(2011) Sandra L. Wilson et al.   CEREBELLUM

Chronic High-Fat Diet Drives Postnatal Epigenetic Regulation of μ-Opioid Receptor in the Brain

(2011) Zivjena Vucetic et al.   NEUROPSYCHOPHARMACOLOGY

No Effect of Folic Acid Supplementation on Global DNA Methylation in Men and Women with Moderately Elevated Homocysteine

(2011) Audrey Y. Jung et al.   PLoS One

Genomic DNA Methylation Changes in Response to Folic Acid Supplementation in a Population-Based Intervention Study among Women of Reproductive Age

(2011) Krista S. Crider et al.   PLoS One

Global DNA methylation measurement by HPLC using low amounts of DNA

(2010) Kelly M. Armstrong et al.   Biotechnology Journal

Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors

(2010) Flora Chik et al.   CARCINOGENESIS

Leptin Gene Epigenetic Adaptation to Impaired Glucose Metabolism During Pregnancy

(2010) L. Bouchard et al.   DIABETES CARE

Breast Cancer DNA Methylation Profiles Are Associated with Tumor Size and Alcohol and Folate Intake

(2010) Brock C. Christensen et al.   PLoS Genetics

Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease

(2009) R Mayor et al.   BRITISH JOURNAL OF CANCER

Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing

(2009) Katherine E. Varley et al.   NUCLEIC ACIDS RESEARCH

Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine

(2008) Carlo Stresemann et al.   INTERNATIONAL JOURNAL OF CANCER