POLQ Overexpression Is Associated with an Increased Somatic Mutation Load and PLK4 Overexpression in Lung Adenocarcinoma

Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes

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Once and only once: mechanisms of centriole duplication and their deregulation in disease

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Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

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TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins

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Multi-Omics Analysis Reveals a HIF Network and Hub Gene EPAS1 Associated with Lung Adenocarcinoma

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Update on Immunohistochemistry for the Diagnosis of Lung Cancer

(2018) Kentaro Inamura   Cancers

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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Defective repair capacity of variant proteins of the DNA glycosylase NTHL1 for 5-hydroxyuracil, an oxidation product of cytosine

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The PLK4–STIL–SAS-6 module at the core of centriole duplication

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Genomic Approaches to Understanding Response and Resistance to Immunotherapy

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DNA polymerase θ (POLQ), double-strand break repair, and cancer

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The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification

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New and emerging targeted treatments in advanced non-small-cell lung cancer

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Reduced expression of the DNA glycosylase gene MUTYH is associated with an increased number of somatic mutations via a reduction in the DNA repair capacity in prostate adenocarcinoma

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Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer

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Mutational signatures associated with tobacco smoking in human cancer

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Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study

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Functional relationship among PLK2, PLK4 and ROCK2 to induce centrosome amplification

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Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues

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Prognostic value of TTF-1 expression in patients with non-small cell lung cancer: A meta-analysis

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BRAF Alterations as Therapeutic Targets in Non–Small-Cell Lung Cancer

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Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

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Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

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Across the Universe of K-Ras Mutations in Non-Small-Cell-Lung Cancer

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Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans

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PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer

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Comprehensive molecular profiling of lung adenocarcinoma

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Oncogene-like induction of cellular invasion from centrosome amplification

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U.S. Food and Drug Administration Approval Summary: Erlotinib for the First-Line Treatment of Metastatic Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor Exon 19 Deletions or Exon 21 (L858R) Substitution Mutations

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A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites

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Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ

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Evidence for APOBEC3B mutagenesis in multiple human cancers

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Identification of upregulated genes in oral squamous cell carcinomas

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DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients

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Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer

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DNA polymerase   up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability

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A mechanism linking extra centrosomes to chromosomal instability

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Induction of centrosome amplification and chromosome instability inp53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE)

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Low-fidelity DNA synthesis by human DNA polymerase theta

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DNA polymerase θ (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct

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