Arsenic Trioxide Impacts Viral Latency and Delays Viral Rebound after Termination of ART in Chronically SIV‐Infected Macaques

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

(2019) Ravindra K. Gupta et al.   NATURE

Novel Latency Reversal Agents for HIV-1 Cure

(2018) Adam M. Spivak et al.   Annual Review of Medicine

Targeting the Latent Reservoir for HIV-1

(2018) Srona Sengupta et al.   IMMUNITY

Risks of cardiovascular or central nervous system adverse events and immune reconstitution inflammatory syndrome, for dolutegravir versus other antiretrovirals

(2018) Andrew M. Hill et al.   Current Opinion in HIV and AIDS

PR-957, a selective immunoproteasome inhibitor, reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1

(2018) Jian Lin et al.   BIOCHEMICAL PHARMACOLOGY

Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C–induced HIV latency reversal

(2018) Kouki Matsuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

(2018) Erica N. Borducchi et al.   NATURE

Relationship between intact HIV-1 proviruses in circulating CD4+ T cells and rebound viruses emerging during treatment interruption

(2018) Ching-Lan Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevention of SIVmac251 reservoir seeding in rhesus monkeys by early antiretroviral therapy

(2018) James B. Whitney et al.   Nature Communications

Immune Protection of SIV Challenge by PD-1 Blockade During Vaccination in Rhesus Monkeys

(2018) Enxiang Pan et al.   Frontiers in Immunology

Arsenic trioxide consolidation in APL

(2017) Manjulika Das   LANCET ONCOLOGY

Structure-optimized dihydropyranoindole derivative GIBH-LRA002 potentially reactivated viral latency in primary CD4+ T lymphocytes of chronic HIV-1 patients

(2017) Qing Yang et al.   MedChemComm

Bryostatin-1 for latent virus reactivation in HIV-infected patients on antiretroviral therapy

(2016) Carolina Gutiérrez et al.   AIDS

Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys

(2016) Dan H. Barouch et al.   CELL

Challenges and strategies for the eradication of the HIV reservoir

(2016) Jason T Kimata et al.   CURRENT OPINION IN IMMUNOLOGY

Preclinical shock strategies to reactivate latent HIV-1

(2016) Gilles Darcis et al.   Current Opinion in HIV and AIDS

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

(2015) Kai Deng et al.   NATURE

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

(2015) D. H. Barouch et al.   SCIENCE

Bryostatin activates HIV-1 latent expression in human astrocytes through a PKC and NF-ĸB-dependent mechanism

(2015) Laura Díaz et al.   Scientific Reports

Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation

(2015) Guochun Jiang et al.   PLoS Pathogens

As2O3 synergistically reactivate latent HIV-1 by induction of NF-κB

(2013) Pengfei Wang et al.   ANTIVIRAL RESEARCH

Proximity to PML Nuclear Bodies Regulates HIV-1 Latency in CD4+ T Cells

(2013) Marina Lusic et al.   Cell Host & Microbe

Histone Deactylase Inhibitor SAHA Induces a Synergistic HIV-1 Reactivation by 12-O-Tetradecanoylphorbol-13-Acetate in Latently Infected Cells

(2013) Soon Young Park et al.   INTERVIROLOGY

Mucosal Priming with a Replicating-Vaccinia Virus-Based Vaccine Elicits Protective Immunity to Simian Immunodeficiency Virus Challenge in Rhesus Monkeys

(2013) C. Sun et al.   JOURNAL OF VIROLOGY

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS

(2013) Iart Shytaj et al.   Retrovirology

SIV infection of rhesus macaques of Chinese origin: a suitable model for HIV infection in humans

(2013) Yu Zhou et al.   Retrovirology

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Vaccine-induced CD8+ T cells control AIDS virus replication

(2012) Philip A. Mudd et al.   NATURE

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro

(2012) Brian A. DeChristopher et al.   Nature Chemistry

Induction of balance and breadth in the immune response is beneficial for the control of SIVmac239 replication in rhesus monkeys

(2010) Caijun Sun et al.   JOURNAL OF INFECTION

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Induction of Cellular Stress Overcomes the Requirement of Herpes Simplex Virus Type 1 for Immediate-Early Protein ICP0 and Reactivates Expression from Quiescent Viral Genomes

(2008) C. M. Preston et al.   JOURNAL OF VIROLOGY