The Mechanical Stimulation of Myotubes Counteracts the Effects of Tumor-Derived Factors Through the Modulation of the Activin/Follistatin Ratio

Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle

(2018) Luigi Formicola et al.   Frontiers in Physiology

Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy

(2017) Frederic Morvan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating Activin A predicts survival in cancer patients

(2017) Audrey Loumaye et al.   Journal of Cachexia Sarcopenia and Muscle

Altered Myokine Secretion Is an Intrinsic Property of Skeletal Muscle in Type 2 Diabetes

(2016) Theodore P. Ciaraldi et al.   PLoS One

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

(2016) Catherine E. Winbanks et al.   Science Translational Medicine

Skeletal muscle Heat shock protein 60 increases after endurance training and induces peroxisome proliferator-activated receptor gamma coactivator 1 α1 expression

(2016) Rosario Barone et al.   Scientific Reports

Activin A induces skeletal muscle catabolism via p38β mitogen-activated protein kinase

(2016) Hui Ding et al.   Journal of Cachexia Sarcopenia and Muscle

Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia

(2016) Dario Coletti et al.   Stem Cells International

Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways

(2016) Rafael Barreto et al.   Frontiers in Physiology

ActRII blockade protects mice from cancer cachexia and prolongs survival in the presence of anti-cancer treatments

(2016) Shinji Hatakeyama et al.   Skeletal Muscle

Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer

(2016) Eva Pigna et al.   Scientific Reports

Complete reversal of muscle wasting in experimental cancer cachexia: Additive effects of activin type II receptor inhibition and β-2 agonist

(2015) Míriam Toledo et al.   INTERNATIONAL JOURNAL OF CANCER

Muscle Extracellular Matrix Scaffold Is a Multipotent Environment

(2015) Paola Aulino et al.   International Journal of Medical Sciences

Role of Activin A and Myostatin in Human Cancer Cachexia

(2015) Audrey Loumaye et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exercise training as treatment in cancer cachexia

(2014) Fábio Santos Lira et al.   Applied Physiology Nutrition and Metabolism

Elevated expression of activins promotes muscle wasting and cachexia

(2013) Justin L. Chen et al.   FASEB JOURNAL

Impaired hypertrophy in myoblasts is improved with testosterone administration

(2013) Colleen S. Deane et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

Resistance exercise modulates lipid plasma profile and cytokine content in the adipose tissue of tumour-bearing rats

(2012) F.F. Donatto et al.   CYTOKINE

Exercise Training Decreases Adipose Tissue Inflammation in Cachectic Rats

(2012) F. Lira et al.   HORMONE AND METABOLIC RESEARCH

InACTIVatINg cancer cachexia

(2011) S. J. Mathew   Disease Models & Mechanisms

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of inflammation in the adipose tissue in cancer cachexia: effect of exercise

(2009) Fábio S. Lira et al.   CELL BIOCHEMISTRY AND FUNCTION

Muscle myostatin signalling is enhanced in experimental cancer cachexia

(2008) P. Costelli et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION