Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

(2018) Michal Zimmermann et al.   NATURE

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

(2018) Konrad Aden et al.   GASTROENTEROLOGY

Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development

(2018) Ryo Uehara et al.   Cell Reports

ImmQuant: a user-friendly tool for inferring immune cell-type composition from gene-expression data

(2016) Amit Frishberg et al.   BIOINFORMATICS

Immunotherapy for breast cancer: past, present, and future

(2016) Alison Spellman et al.   CANCER AND METASTASIS REVIEWS

Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response

(2016) Karen J Mackenzie et al.   EMBO JOURNAL

RNase H2 catalytic core Aicardi-Goutières syndrome–related mutant invokes cGAS–STING innate immune-sensing pathway in mice

(2016) Vladislav Pokatayev et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DNA-Sensing and Nuclease Gene Expressions as Markers for Colorectal Cancer Progression

(2016) Chin-An Yang et al.   ONCOLOGY

Is the role of human RNase H2 restricted to its enzyme activity?

(2016) Shaolong Feng et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

An Integrated Genome-Wide Systems Genetics Screen for Breast Cancer Metastasis Susceptibility Genes

(2016) Ling Bai et al.   PLoS Genetics

Characterization of human disease phenotypes associated with mutations inTREX1,RNASEH2A,RNASEH2B,RNASEH2C,SAMHD1,ADAR, andIFIH1

(2015) Yanick J. Crow et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Rare Coding Variants and Breast Cancer Risk: Evaluation of Susceptibility Loci Identified in Genome-Wide Association Studies

(2014) Y. Zhang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Cytosolic RNA:DNA hybrids activate the cGAS–STING axis

(2014) Arun K Mankan et al.   EMBO JOURNAL

Identification of novel genes involved in gastric carcinogenesis by suppression subtractive hybridization

(2014) N Mottaghi-Dastjerdi et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Altered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi–Goutières syndrome

(2014) Barbara Kind et al.   HUMAN MOLECULAR GENETICS

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity

(2014) Claudia Günther et al.   JOURNAL OF CLINICAL INVESTIGATION

The enemy within: endogenous retroelements and autoimmune disease

(2014) Hannah E Volkman et al.   NATURE IMMUNOLOGY

A Systems Genetics Approach Identifies CXCL14, ITGAX, and LPCAT2 as Novel Aggressive Prostate Cancer Susceptibility Genes

(2014) Kendra A. Williams et al.   PLoS Genetics

An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease

(2013) F. Faraji et al.   GENOME RESEARCH

Genetic Background May Contribute to PAM50 Gene Expression Breast Cancer Subtype Assignments

(2013) Ying Hu et al.   PLoS One

BRD4 Short Isoform Interacts with RRP1B, SIPA1 and Components of the LINC Complex at the Inner Face of the Nuclear Membrane

(2013) Jude Alsarraj et al.   PLoS One

High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population

(2012) Karen L. Svenson et al.   GENETICS

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity

(2012) Bjoern Hiller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Allelic Variation and Differential Expression of the mSIN3A Histone Deacetylase Complex Gene Arid4b Promote Mammary Tumor Growth and Metastasis

(2012) Scott F. Winter et al.   PLoS Genetics

Cadm1 Is a Metastasis Susceptibility Gene That Suppresses Metastasis by Modifying Tumor Interaction with the Cell-Mediated Immunity

(2012) Farhoud Faraji et al.   PLoS Genetics

IRF7: activation, regulation, modification and function

(2011) S Ning et al.   GENES AND IMMUNITY

GOBO: Gene Expression-Based Outcome for Breast Cancer Online

(2011) Markus Ringnér et al.   PLoS One

The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

(2010) Martin A. M. Reijns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome instability due to ribonucleotide incorporation into DNA

(2010) Stephanie A Nick McElhinny et al.   Nature Chemical Biology

Ribonuclease H: the enzymes in eukaryotes

(2009) Susana M. Cerritelli et al.   FEBS Journal

The Structure of the Mammalian RNase H2 Complex Provides Insight into RNA·DNA Hybrid Processing to Prevent Immune Dysfunction

(2009) Nadine M. Shaban et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomics screen in transformed stem cells reveals RNASEH2A, PPAP2C, and ADARB1 as putative anticancer drug targets

(2009) J. M. Flanagan et al.   MOLECULAR CANCER THERAPEUTICS

The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival

(2008) Nigel P. S. Crawford et al.   CLINICAL & EXPERIMENTAL METASTASIS

RNaseH2 mutants that cause Aicardi–Goutieres syndrome are active nucleases

(2008) Fred W. Perrino et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY

Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex

(2008) Hyongi Chon et al.   NUCLEIC ACIDS RESEARCH

Bromodomain 4 activation predicts breast cancer survival

(2008) N. P. S. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA