Aneuploidy drives lethal progression in prostate cancer

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

(2018) Alison M. Taylor et al.   CANCER CELL

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017

(2018) Silke Gillessen et al.   EUROPEAN UROLOGY

Genome doubling shapes the evolution and prognosis of advanced cancers

(2018) Craig M. Bielski et al.   NATURE GENETICS

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

(2018) David C. Wedge et al.   NATURE GENETICS

The Epidemiology of Prostate Cancer

(2018) Claire H. Pernar et al.   Cold Spring Harbor Perspectives in Medicine

Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

(2018) Haley Hieronymus et al.   eLife

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

(2017) Niedzica Camacho et al.   PLoS Genetics

Association of Prostate Cancer Risk Variants with TMPRSS2:ERG Status: Evidence for Distinct Molecular Subtypes

(2016) K. L. Penney et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Prognostic Utility of a New mRNA Expression Signature of Gleason Score

(2016) Jennifer A. Sinnott et al.   CLINICAL CANCER RESEARCH

Genomic Correlates to the Newly Proposed Grading Prognostic Groups for Prostate Cancer

(2016) Mark A. Rubin et al.   EUROPEAN UROLOGY

Deletions linked to TP53 loss drive cancer through p53-independent mechanisms

(2016) Yu Liu et al.   NATURE

The Molecular Taxonomy of Primary Prostate Cancer

(2015) Adam Abeshouse et al.   CELL

Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes

(2015) Megan E. Bonney et al.   GENES & DEVELOPMENT

A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer

(2015) Thomas U. Ahearn et al.   JNCI-Journal of the National Cancer Institute

Revisiting tumour aneuploidy — the place of ploidy assessment in the molecular era

(2015) Håvard E. Danielsen et al.   Nature Reviews Clinical Oncology

A Prospective Investigation of PTEN Loss and ERG Expression in Lethal Prostate Cancer

(2015) Thomas U. Ahearn et al.   JNCI-Journal of the National Cancer Institute

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

(2014) Emilie Lalonde et al.   LANCET ONCOLOGY

Prostate Cancer Ki-67 (MIB-1) Expression, Perineural Invasion, and Gleason Score as Biopsy-Based Predictors of Prostate Cancer Mortality: The Mayo Model

(2014) Matthew K. Tollefson et al.   MAYO CLINIC PROCEEDINGS

Copy number alteration burden predicts prostate cancer relapse

(2014) H. Hieronymus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues

(2014) Kristin A. Knouse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis

(2013) J. M. Sheltzer   CANCER RESEARCH

Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

(2013) Teresa Davoli et al.   CELL

Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors

(2013) A. D. Silk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The consequences of chromosomal aneuploidy on the transcriptome of cancer cells

(2012) Thomas Ried et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Gleason Score and Lethal Prostate Cancer: Does 3 + 4 = 4 + 3?

(2009) Jennifer R. Stark et al.   JOURNAL OF CLINICAL ONCOLOGY

Chromosomal instability determines taxane response

(2009) C. Swanton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells

(2008) B. R. Williams et al.   SCIENCE