Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway

miR-142-3p inhibits aerobic glycolysis and cell proliferation in hepatocellular carcinoma via targeting LDHA

(2018) Shengni Hua et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction

(2018) Lijun Jia et al.   LIFE SCIENCES

Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation

(2018) Thomas G. Blanchard et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Resveratrol inhibits VEGF-induced angiogenesis in human endothelial cells associated with suppression of aerobic glycolysis via modulation of PKM2 nuclear translocation

(2018) Hongyan Wu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2

(2017) Dong Xu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Candesartan attenuates angiogenesis in hepatocellular carcinoma via downregulating AT1R/VEGF pathway

(2016) Fangtian Fan et al.   BIOMEDICINE & PHARMACOTHERAPY

Prognostic significance of synergistic hexokinase-2 and beta2-adrenergic receptor expression in human hepatocelluar carcinoma after curative resection

(2016) Zhi-Feng Zhang et al.   BMC GASTROENTEROLOGY

Resveratrol inhibits Hexokinases II mediated glycolysis in non-small cell lung cancer via targeting Akt signaling pathway

(2016) Wei Li et al.   EXPERIMENTAL CELL RESEARCH

New Approach for Treatment of Primary Liver Tumors: The Role of Quercetin

(2016) Ana Filipa Brito et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Quercetin Regresses Dalton's Lymphoma Growth via Suppression of PI3K/AKT Signaling Leading to Upregulation of p53 and Decrease in Energy Metabolism

(2015) Akhilendra Kumar Maurya et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation

(2015) Valeria Iansante et al.   Nature Communications

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

(2015) Weiqi Dai et al.   Oncotarget

BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction

(2014) Eui Young So et al.   BMC CANCER

How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions?

(2014) H Lincet et al.   ONCOGENE

Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism

(2013) Liliana Moreira et al.   EXPERIMENTAL CELL RESEARCH

Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy

(2013) George S Krasnov et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

(2012) Chia-Hsin Chan et al.   CELL

Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death

(2012) E. C. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The flavonoid quercetin in disease prevention and therapy: Facts and fancies

(2011) Maria Russo et al.   BIOCHEMICAL PHARMACOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition

(2010) R. Vidya Priyadarsini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2

(2010) Manti Guha et al.   MOLECULAR BIOLOGY OF THE CELL

Hepatocellular carcinoma: a global view

(2010) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

The Incidence and Epidemiology of Hepatocellular Carcinoma: A Global and Regional Perspective

(2010) A. P. Venook et al.   ONCOLOGIST

The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

(2010) A. J. Levine et al.   SCIENCE

Hepatocellular Carcinoma – Epidemiological Trends and Risk Factors

(2009) Kerstin Schütte et al.   DIGESTIVE DISEASES

Flavonoids Intake and Risk of Lung Cancer: A Meta-analysis

(2009) N.-P. Tang et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Synergistic Effect of Functionalized Nickel Nanoparticles and Quercetin on Inhibition of the SMMC-7721 Cells Proliferation

(2009) Dadong Guo et al.   Nanoscale Research Letters

Dietary flavonoid intake and lung cancer-A population-based case-control study

(2008) Yan Cui et al.   CANCER