BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction

Inhibition of Akt Potentiates 2-DG-Induced Apoptosis via Downregulation of UPR in Acute Lymphoblastic Leukemia

(2012) J. DeSalvo et al.   MOLECULAR CANCER RESEARCH

Genetic Mapping and Exome Sequencing Identify Variants Associated with Five Novel Diseases

(2012) Erik G. Puffenberger et al.   PLoS One

Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death

(2012) H. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Whole-Genome Sequencing for Genetic Disease Diagnosis in Neonatal Intensive Care Units

(2012) C. J. Saunders et al.   Science Translational Medicine

Mitochondrial dysfunction in ataxia-telangiectasia

(2011) Y. A. Valentin-Vega et al.   BLOOD

β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

(2011) Kyung-Ran Park et al.   CANCER LETTERS

p38 MAPK-Mediated Bmi-1 Down-Regulation and Defective Proliferation in ATM-Deficient Neural Stem Cells Can Be Restored by Akt Activation

(2011) Jeesun Kim et al.   PLoS One

Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2

(2010) Manti Guha et al.   MOLECULAR BIOLOGY OF THE CELL

Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1a and HIF-2a target genes

(2010) Sang Y Chun et al.   Molecular Cancer

ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation

(2010) Takeshi Uchiumi et al.   NUCLEIC ACIDS RESEARCH

Silencing of PTK7 in Colon Cancer Cells: Caspase-10-Dependent Apoptosis via Mitochondrial Pathway

(2010) Ling Meng et al.   PLoS One

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Expression and Maintenance of Mitochondrial DNA

(2008) Gerald S. Shadel   AMERICAN JOURNAL OF PATHOLOGY

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance

(2008) Chun-Wun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY