Optimizing selectivity of anion hydrophobic multimodal chromatography for purification of a single‐chain variable fragment

Domain contributions to antibody retention in multimodal chromatography systems

(2018) Julie Robinson et al.   JOURNAL OF CHROMATOGRAPHY A

Simultaneous Optimization of Biomolecular Energy Functions on Features from Small Molecules and Macromolecules

(2016) Hahnbeom Park et al.   Journal of Chemical Theory and Computation

Designing monoclonal antibody fragment-based affinity resins with high binding capacity by thiol-directed immobilisation and optimisation of pore/ligand size ratio

(2016) Laila Ismail Sakhnini et al.   JOURNAL OF CHROMATOGRAPHY A

Investigation of protein selectivity in multimodal chromatography usingin silicodesigned Fab fragment variants

(2015) Hanne Sophie Karkov et al.   BIOTECHNOLOGY AND BIOENGINEERING

Purification process of recombinant monoclonal antibodies with mixed mode chromatography

(2015) Sophie Maria et al.   JOURNAL OF CHROMATOGRAPHY A

Evaluation of selectivity in homologous multimodal chromatographic systems using in silico designed antibody fragment libraries

(2015) Hanne Sophie Karkov et al.   JOURNAL OF CHROMATOGRAPHY A

Evaluation of high-capacity cation exchange chromatography for direct capture of monoclonal antibodies from high-titer cell culture processes

(2014) Yinying Tao et al.   BIOTECHNOLOGY AND BIOENGINEERING

Process development of periplasmatically produced single chain fragment variable against epidermal growth factor receptor in Escherichia coli

(2014) Robert Lindner et al.   JOURNAL OF BIOTECHNOLOGY

Improving Monoclonal Antibody Selection and Engineering using Measurements of Colloidal Protein Interactions

(2014) Steven B. Geng et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Systematic generation of buffer systems for pH gradient ion exchange chromatography and their application

(2013) Frieder Kröner et al.   JOURNAL OF CHROMATOGRAPHY A

Evaluating antibody monomer separation from associated aggregates using mixed-mode chromatography

(2013) Dong Gao et al.   JOURNAL OF CHROMATOGRAPHY A

A Pareto-Optimal Refinement Method for Protein Design Scaffolds

(2013) Lucas Gregorio Nivón et al.   PLoS One

High-Resolution Comparative Modeling with RosettaCM

(2013) Yifan Song et al.   STRUCTURE

Antibody capture by mixed-mode chromatography: A comprehensive study from determination of optimal purification conditions to identification of contaminating host cell proteins

(2011) Jerome Pezzini et al.   JOURNAL OF CHROMATOGRAPHY A

Designing new monoclonal antibody purification processes using mixed-mode chromatography sorbents

(2011) Magali Toueille et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

HHblits: lightning-fast iterative protein sequence searching by HMM-HMM alignment

(2011) Michael Remmert et al.   NATURE METHODS

RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite

(2011) Sarel J. Fleishman et al.   PLoS One

Prediction of Aggregation Prone Regions of Therapeutic Proteins

(2010) Naresh Chennamsetty et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Potential aggregation prone regions in biotherapeutics

(2010) Xiaoling Wang et al.   mAbs

Grafting of protein L-binding activity onto recombinant antibody fragments

(2009) Julien Muzard et al.   ANALYTICAL BIOCHEMISTRY

Applications of single-chain variable fragment antibodies in therapeutics and diagnostics

(2009) Nina E. Weisser et al.   BIOTECHNOLOGY ADVANCES

The distinctive separation attributes of mixed-mode resins and their application in monoclonal antibody downstream purification process

(2009) Jie Chen et al.   JOURNAL OF CHROMATOGRAPHY A

Aggregation-Prone Motifs in Human Immunoglobulin G

(2009) Naresh Chennamsetty et al.   JOURNAL OF MOLECULAR BIOLOGY

Design of therapeutic proteins with enhanced stability

(2009) N. Chennamsetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput screening of chromatographic separations: III. Monoclonal antibodies on ceramic hydroxyapatite

(2008) David L. Wensel et al.   BIOTECHNOLOGY AND BIOENGINEERING