Investigation of protein selectivity in multimodal chromatography usingin silicodesigned Fab fragment variants

Model-based process development for the purification of a modified human growth hormone using multimodal chromatography

(2014) Lars Sejergaard et al.   BIOTECHNOLOGY PROGRESS

Interaction of arginine with Capto MMC in multimodal chromatography

(2014) Atsushi Hirano et al.   JOURNAL OF CHROMATOGRAPHY A

Evaluation of a multimodal resin for selective capture of CHO-derived monoclonal antibodies directly from harvested cell culture fluid

(2014) Kimberly A. Kaleas et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Application of a Spherical Harmonics Expansion Approach for Calculating Ligand Density Distributions around Proteins

(2014) Siddharth Parimal et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Investigation into the Molecular and Thermodynamic Basis of Protein Interactions in Multimodal Chromatography Using Functionalized Nanoparticles

(2014) Kartik Srinivasan et al.   LANGMUIR

Methods development in multimodal chromatography with mobile phase modifiers using the steric mass action model

(2013) Hanne Sophie Karkov et al.   JOURNAL OF CHROMATOGRAPHY A

Multimodal chromatography: An efficient tool in downstream processing of proteins

(2012) Kristian Kallberg et al.   Biotechnology Journal

Probing multimodal ligand binding regions on ubiquitin using nuclear magnetic resonance, chromatography, and molecular dynamics simulations

(2012) Melissa A. Holstein et al.   JOURNAL OF CHROMATOGRAPHY A

Preparation of a novel dual-function strong cation exchange/hydrophobic interaction chromatography stationary phase for protein separation

(2012) Kailou Zhao et al.   TALANTA

Engineering Aggregation-Resistant Antibodies

(2012) Joseph M. Perchiacca et al.   Annual Review of Chemical and Biomolecular Engineering

Mobile phase modifier effects in multimodal cation exchange chromatography

(2011) Melissa A. Holstein et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of selectivity in multimodal anion exchange systems: A priori prediction of protein retention and examination of mobile phase modifier effects

(2011) Ying Hou et al.   JOURNAL OF CHROMATOGRAPHY A

Aggregation in Protein-Based Biotherapeutics: Computational Studies and Tools to Identify Aggregation-Prone Regions

(2011) Neeraj J. Agrawal et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Developability Index: A Rapid In Silico Tool for the Screening of Antibody Aggregation Propensity

(2011) Timothy M. Lauer et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Molecular Simulations of Multimodal Ligand–Protein Binding: Elucidation of Binding Sites and Correlation with Experiments

(2011) Alexander S. Freed et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Downstream bioprocessing: recent advances and future promise

(2011) Steven M Cramer et al.   Current Opinion in Chemical Engineering

3D structure-based protein retention prediction for ion-exchange chromatography

(2010) Florian Dismer et al.   JOURNAL OF CHROMATOGRAPHY A

High-throughput isotherm determination and thermodynamic modeling of protein adsorption on mixed mode adsorbents

(2010) Beckley K. Nfor et al.   JOURNAL OF CHROMATOGRAPHY A

Prediction of Aggregation Prone Regions of Therapeutic Proteins

(2010) Naresh Chennamsetty et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Charge variants in IgG1

(2010) Leslie A. Khawli et al.   mAbs

Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR

(2010) W. K. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library

(2009) Wai Keen Chung et al.   JOURNAL OF CHROMATOGRAPHY A

Aggregation-Prone Motifs in Human Immunoglobulin G

(2009) Naresh Chennamsetty et al.   JOURNAL OF MOLECULAR BIOLOGY

Utilization of Lysozyme Charge Ladders to Examine the Effects of Protein Surface Charge Distribution on Binding Affinity in Ion Exchange Systems

(2009) Wai Keen Chung et al.   LANGMUIR

Design of therapeutic proteins with enhanced stability

(2009) N. Chennamsetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Separation of populations of antibody variants by fine tuning of hydrophobic-interaction chromatography operating conditions

(2008) John Valliere-Douglass et al.   JOURNAL OF CHROMATOGRAPHY A

The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies

(2008) Sara Birtalan et al.   JOURNAL OF MOLECULAR BIOLOGY