标题
EMT Regulation by Autophagy: A New Perspective in Glioblastoma Biology
作者
关键词
-
出版物
Cancers
Volume 11, Issue 3, Pages 312
出版商
MDPI AG
发表日期
2019-03-07
DOI
10.3390/cancers11030312
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
- (2018) Mario Mauthe et al. Autophagy
- Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells
- (2018) Javad Alizadeh et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Autophagy contributes to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis†
- (2018) Hengwei Liu et al. BIOLOGY OF REPRODUCTION
- Mesenchymal stem cells promote cell invasion and migration and autophagy-induced epithelial-mesenchymal transition in A549 lung adenocarcinoma cells
- (2018) Dan Luo et al. CELL BIOCHEMISTRY AND FUNCTION
- Knockdown of Beclin-1 impairs epithelial-mesenchymal transition of colon cancer cells
- (2018) Hong Shen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A brief history of autophagy from cell biology to physiology and disease
- (2018) Noboru Mizushima NATURE CELL BIOLOGY
- PP242 Counteracts Glioblastoma Cell Proliferation, Migration, Invasiveness and Stemness Properties by Inhibiting mTORC2/AKT
- (2018) Carmen Mecca et al. Frontiers in Cellular Neuroscience
- DRAM1 regulates the migration and invasion of hepatoblastoma cells via autophagy‑EMT pathway
- (2018) Chao Chen et al. Oncology Letters
- Autophagy induces transforming growth factor-β-dependent epithelial-mesenchymal transition in hepatocarcinoma cells through cAMP response element binding signalling
- (2018) Shaobo Hu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Maternal exposure to di-n-butyl phthalate (DBP) promotes epithelial-mesenchymal transition via regulation of autophagy in uroepithelial cell
- (2018) Sheng Zhao et al. TOXICOLOGY
- Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells
- (2018) Barbara Colella et al. CELLULAR SIGNALLING
- Starvation-induced autophagy promotes the invasion and migration of human bladder cancer cells via TGF-β1/Smad3-mediated epithelial-mesenchymal transition activation
- (2018) Hang Tong et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- HGF induces EMT in non-small-cell lung cancer through the hBVR pathway
- (2017) Fang Liu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The role of autophagy in the cross-talk between epithelial-mesenchymal transitioned tumor cells and cancer stem-like cells
- (2017) Fabrizio Marcucci et al. Molecular Cancer
- Autophagy regulates TGF-β2-induced epithelial-mesenchymal transition in human retinal pigment epithelium cells
- (2017) Jing Wu et al. Molecular Medicine Reports
- The critical role of EGF-β-catenin signaling in the epithelial-mesenchymal transition in human glioblastoma
- (2017) Xingqiang Wang et al. OncoTargets and Therapy
- Autophagy inhibition impairs the epithelial-mesenchymal transition and enhances cisplatin sensitivity in nasopharyngeal carcinoma
- (2017) Zhongwu Su et al. Oncology Letters
- From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home
- (2017) Margaret M. Harnett et al. Biomedical Journal
- Suppression of autophagy impedes glioblastoma development and induces senescence
- (2016) Noor Gammoh et al. Autophagy
- Inhibition of Autophagy by Chloroquine Enhances the Antitumor Efficacy of Sorafenib in Glioblastoma
- (2016) Xiangyu Liu et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- The Epithelial-to-Mesenchymal Transition-Like Process in Glioblastoma: An Updated Systematic Review and In Silico Investigation
- (2016) Isabele C. Iser et al. MEDICINAL RESEARCH REVIEWS
- Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancer
- (2016) Mila Gugnoni et al. Cell Death & Disease
- AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition
- (2016) Meijuan Zou et al. Oncotarget
- EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells
- (2016) Jinkyoung Kim et al. Oncotarget
- MicroRNA Regulation of Epithelial to Mesenchymal Transition
- (2016) Mohammed Abba et al. Journal of Clinical Medicine
- Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition
- (2016) Ramadevi Subramani et al. Scientific Reports
- MIR517Cinhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation
- (2015) Yuntao Lu et al. Autophagy
- Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage
- (2015) Eduardo Cremonese Filippi-Chiela et al. Autophagy
- Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes
- (2015) Sheila R. Alcantara Llaguno et al. CANCER CELL
- Enhanced Epithelial-to-Mesenchymal Transition Associated with Lysosome Dysfunction in Podocytes: Role of p62/Sequestosome 1 as a Signaling Hub
- (2015) Guangbi Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Autophagy in malignant transformation and cancer progression
- (2015) L. Galluzzi et al. EMBO JOURNAL
- Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells
- (2015) Dan Zi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells
- (2015) Bao-Jun Ren et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas
- (2015) CAROLIN KUBELT et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Autophagy: a druggable process that is deregulated in aging and human disease
- (2015) Guido Kroemer JOURNAL OF CLINICAL INVESTIGATION
- WNT signaling in glioblastoma and therapeutic opportunities
- (2015) Yeri Lee et al. LABORATORY INVESTIGATION
- Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells
- (2015) Myriam Catalano et al. Molecular Oncology
- Erratum: Corrigendum: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation
- (2015) Valentina Cianfanelli et al. NATURE CELL BIOLOGY
- Beyond β-catenin: prospects for a larger catenin network in the nucleus
- (2015) Pierre D. McCrea et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Emerging strategies to effectively target autophagy in cancer
- (2015) V W Rebecca et al. ONCOGENE
- Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
- (2015) Mona Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Current treatment strategies for inhibiting mTOR in cancer
- (2015) Francesca Chiarini et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation
- (2015) G Grassi et al. Cell Death & Disease
- Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells
- (2015) Wenjie Qin et al. Oncotarget
- ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-κB-dependent activation of Snail
- (2015) Magdalena A. Cichon et al. Oncotarget
- A radiosensitivity gene signature in predicting glioma prognostic via EMT pathway
- (2015) Jin Meng et al. Oncotarget
- BH3 Mimetics Reactivate Autophagic Cell Death in Anoxia-Resistant Malignant Glioma Cells
- (2015) Holger Hetschko et al. NEOPLASIA
- Autophagy revisited: A conversation with Christian de Duve
- (2014) Daniel J. Klionsky Autophagy
- Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition
- (2014) Lei Qiang et al. Autophagy
- A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
- (2014) Myrna R Rosenfeld et al. Autophagy
- Radiation promotes malignant progression of glioma cells through HIF-1alpha stabilization
- (2014) Young-Heon Kim et al. CANCER LETTERS
- Molecular Pathways: Linking Tumor Microenvironment to Epithelial-Mesenchymal Transition in Metastasis
- (2014) H.-Y. Jung et al. CLINICAL CANCER RESEARCH
- Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects
- (2014) T. T. Batchelor et al. CLINICAL CANCER RESEARCH
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- A cadherin switch underlies malignancy in high-grade gliomas
- (2014) I Appolloni et al. ONCOGENE
- Micro-Environment Causes Reversible Changes in DNA Methylation and mRNA Expression Profiles in Patient-Derived Glioma Stem Cells
- (2014) Mehmet Baysan et al. PLoS One
- Regulation of cell proliferation and migration by p62 through stabilization of Twist1
- (2014) L. Qiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift
- (2014) J. Halliday et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic control of cell death
- (2014) D. R. Green et al. SCIENCE
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Degradation of mutant p53H175 protein by Zn(II) through autophagy
- (2014) A Garufi et al. Cell Death & Disease
- TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion
- (2014) J V Joseph et al. Cell Death & Disease
- A dual role for autophagy in a murine model of lung cancer
- (2014) Shuan Rao et al. Nature Communications
- Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors
- (2014) J. M. M. Levy et al. Cancer Discovery
- Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells
- (2013) Yuan-Fei Peng et al. Autophagy
- The ULK1 complex
- (2013) Pui-Mun Wong et al. Autophagy
- Bif-1 haploinsufficiency promotes chromosomal instability and accelerates Myc-driven lymphomagenesis via suppression of mitophagy
- (2013) Y. Takahashi et al. BLOOD
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- The MET Oncogene in Glioblastoma Stem Cells: Implications as a Diagnostic Marker and a Therapeutic Target
- (2013) C. Boccaccio et al. CANCER RESEARCH
- Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial–mesenchymal transition
- (2013) Jun Li et al. CARCINOGENESIS
- Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling
- (2013) A Ko et al. CELL DEATH AND DIFFERENTIATION
- The machinery of macroautophagy
- (2013) Yuchen Feng et al. CELL RESEARCH
- Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition
- (2013) Y. Piao et al. CLINICAL CANCER RESEARCH
- The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance
- (2013) Florian A. Siebzehnrubl et al. EMBO Molecular Medicine
- Autophagy and Cellular Immune Responses
- (2013) Yuting Ma et al. IMMUNITY
- IKK controls canonical TGF -SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells
- (2013) M. Brandl et al. JOURNAL OF CELL SCIENCE
- Emerging regulation and functions of autophagy
- (2013) Patricia Boya et al. NATURE CELL BIOLOGY
- Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma
- (2013) Roshan Mahabir et al. NEURO-ONCOLOGY
- Investigating the Link between Molecular Subtypes of Glioblastoma, Epithelial-Mesenchymal Transition, and CD133 Cell Surface Protein
- (2013) Hadi Zarkoob et al. PLoS One
- Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors
- (2013) A. M. Strohecker et al. Cancer Discovery
- DEDD, a novel tumor repressor, reverses epithelial-mesenchymal transition by activating selective autophagy
- (2012) Qi Lv et al. Autophagy
- Pathogenic role of HIF-1α in prostate hyperplasia in the presence of chronic inflammation
- (2012) Hye-Jin Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas
- (2012) U.D. Kahlert et al. CANCER LETTERS
- Clusterin Mediates TGF- -Induced Epithelial-Mesenchymal Transition and Metastasis via Twist1 in Prostate Cancer Cells
- (2012) M. Shiota et al. CANCER RESEARCH
- The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
- (2012) F. De Bacco et al. CANCER RESEARCH
- DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial-Mesenchymal Transition in Human Breast Cancer
- (2012) Q. Lv et al. CANCER RESEARCH
- Emerging roles of PDGF-D in EMT progression during tumorigenesis
- (2012) Qiong Wu et al. CANCER TREATMENT REVIEWS
- N-cadherin expression level modulates integrin-mediated polarity and strongly impacts on the speed and directionality of glial cell migration
- (2012) Emeline Camand et al. JOURNAL OF CELL SCIENCE
- Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments
- (2012) Silvia Palumbo et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells
- (2012) S Galavotti et al. ONCOGENE
- ZEB2 Mediates Multiple Pathways Regulating Cell Proliferation, Migration, Invasion, and Apoptosis in Glioma
- (2012) Songtao Qi et al. PLoS One
- mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways
- (2011) P. Gulhati et al. CANCER RESEARCH
- Blockade of TGF- Signaling by the TGF R-I Kinase Inhibitor LY2109761 Enhances Radiation Response and Prolongs Survival in Glioblastoma
- (2011) M. Zhang et al. CANCER RESEARCH
- Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma
- (2011) Chong Liu et al. CELL
- Autophagy is required for self-renewal and differentiation of adult human stem cells
- (2011) Souzan Salemi et al. CELL RESEARCH
- SNAI1 is Involved in the Proliferation and Migration of Glioblastoma Cells
- (2011) Sung-Pil Han et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Autophagy-deficient mice develop multiple liver tumors
- (2011) A. Takamura et al. GENES & DEVELOPMENT
- The basics of epithelial-mesenchymal transition
- (2011) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
- (2011) S. Torres et al. MOLECULAR CANCER THERAPEUTICS
- The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Induces Tumor Regression in a Genetically Engineered Mouse Model of PIK3CA Wild-Type Colorectal Cancer
- (2011) Jatin Roper et al. PLoS One
- -catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
- (2011) E. Sanchez-Tillo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
- (2011) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SNAI2/Slug promotes growth and invasion in human gliomas
- (2010) Hong Wei Yang et al. BMC CANCER
- TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma
- (2010) Judit Anido et al. CANCER CELL
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- mTOR-Mediated Activation of p70 S6K Induces Differentiation of Pluripotent Human Embryonic Stem Cells
- (2010) Charles A. Easley et al. Cellular Reprogramming
- The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
- (2010) Sabrina Di Bartolomeo et al. JOURNAL OF CELL BIOLOGY
- TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype
- (2010) Gianluca Storci et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors
- (2010) Xin Huang et al. JOURNAL OF CLINICAL NEUROSCIENCE
- TWIST1 promotes invasion through mesenchymal change in human glioblastoma
- (2010) Svetlana A Mikheeva et al. Molecular Cancer
- The Pan-Bcl-2 Inhibitor (-)-Gossypol Triggers Autophagic Cell Death in Malignant Glioma
- (2010) V. Voss et al. MOLECULAR CANCER RESEARCH
- Misregulated E-Cadherin Expression Associated with an Aggressive Brain Tumor Phenotype
- (2010) Laura J. Lewis-Tuffin et al. PLoS One
- The Role of Autophagy During Development in Higher Eukaryotes
- (2010) Sabrina Di Bartolomeo et al. TRAFFIC
- The prognostic role of Beclin 1 protein expression in high-grade gliomas
- (2009) Luigi Pirtoli et al. Autophagy
- Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model
- (2009) Sheila Alcantara Llaguno et al. CANCER CELL
- Autophagy Suppresses Tumorigenesis through Elimination of p62
- (2009) Robin Mathew et al. CELL
- mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging
- (2009) Rogerio M. Castilho et al. Cell Stem Cell
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- mTOR signaling at a glance
- (2009) M. Laplante et al. JOURNAL OF CELL SCIENCE
- A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition
- (2009) Theresa Vincent et al. NATURE CELL BIOLOGY
- Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
- (2009) Yun Zhong et al. NATURE CELL BIOLOGY
- Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
- (2009) Kohichi Matsunaga et al. NATURE CELL BIOLOGY
- Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma
- (2009) N Lindberg et al. ONCOGENE
- Prognostic significance of c-Met expression in glioblastomas
- (2008) Doo-Sik Kong et al. CANCER
- Redox mechanisms switch on hypoxia-dependent epithelial–mesenchymal transition in cancer cells
- (2008) Stefania Cannito et al. CARCINOGENESIS
- Combination of Vascular Endothelial Growth Factor Receptor/Platelet-Derived Growth Factor Receptor Inhibition Markedly Improves Radiation Tumor Therapy
- (2008) C. Timke et al. CLINICAL CANCER RESEARCH
- Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells
- (2008) T Yokoyama et al. GENE THERAPY
- Delta-24-RGD in Combination With RAD001 Induces Enhanced Anti-glioma Effect via Autophagic Cell Death
- (2008) Marta M Alonso et al. MOLECULAR THERAPY
- Direct regulation of TWIST by HIF-1α promotes metastasis
- (2008) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Regulation of autophagy by cytoplasmic p53
- (2008) Ezgi Tasdemir et al. NATURE CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search